Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions

Journal of Allergy and Clinical Immunology

Volumn 106, Issue 6, 2000, Pages 1171-1176

  Yawalkar, Nikhil ^a,b   Shrikhande, Maithili ^a,b   Hari, Yvonne ^a   Nievergelt, Helga ^b   Braathen, Lasse R ^b   Pichler, Werner J ^a  

^a Clinic for Rheumatology   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Drug allergy; Eotaxin; IL 5; IL 8; Immunohistochemistry; Monocyte chemoattractant protein 3; Psoriasis; RANTES

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CARBAMAZEPINE; CEFAZOLIN; EOTAXIN; INDAPAMIDE; INTERLEUKIN 5; INTERLEUKIN 8; METOLAZONE; MONOCYTE CHEMOTACTIC PROTEIN 3; PREDNISOLONE; RANTES; VITAMIN B COMPLEX;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ERUPTION; EOSINOPHIL; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE TRANSFORMATION; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PSORIASIS; RASH; SKIN ALLERGY; SKIN BIOPSY;

EID: 0034538071     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1067/mai.2000.110922     Document Type: Article

References (28)

1. Infiltration of cytotoxic T cells in drug-induced cutaneous eruptions
2. Pathophysiology of drug-elicited exanthems
3. Mechanisms of eosinophil-associated inflammation
4. Chemokines in allergy
5. Chemokines and allergic disease
6. Eotaxin from an eosinophilic chemokine to a major regulator of allergic reactions
7. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
8. The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity
9. Drug-induced linear IgA bullous dermatosis associated with ceftriaxone- and metronidazole-specific T cells
10. The lymphocyte transformation test for the diagnosis of drug allergy: Sensitivity and specificity
11. Antigen-presenting cells and keratinocytes express Interleukin 12 in allergic contact dermatitis
12. Drug eruptions causative agents and clinical types. A series of in-patients during a 10-year period
13. Cutaneous drug reactions. An attempt to quantitative estimation
14. T cell reactivity to penicillin: Phenotypic analysis of in vitro activated cell subsets
15. T cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug-specific and cytotoxic
16. Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals
17. Characterization of lidocaine-specific T cells
18. Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alpha/beta T cell clones
19. T cell cytotoxicity in sulfamethoxazole induced skin reaction
20. Distinct serum cytokine levels in drug and measles induced exanthema
21. Interleukin-5, eosinophils, and disease
22. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: Association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (monocyte chemoattractant protein-3 and RANTES)
23. Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis
24. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia
25. Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow
26. Eotaxin modulates myelopoiesis and mast cell development from embryonic hematopoietic progenitors
27. Symptomatology and markers of the severity of erythematous drug eruptions