Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: Implications for hapten formation

Chemical Research in Toxicology

Volumn 22, Issue 5, 2009, Pages 937-948

  Callan, Hayley E ^a   Jenkins, Rosalind E ^a   Maggs, James L ^a   Lavergne, Sidonie N ^a   Clarke, Stephen E ^b   Naisbitt, Dean J ^a   Kevin Park, B ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DRUG METABOLITE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HAPTEN; NITROSO SULFAMETHOXAZOLE; SERUM ALBUMIN; SULFAMETHOXAZOLE; SULFINAMIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MASS SPECTROMETRY; NONHUMAN;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HAPTENS; HUMANS; MASS SPECTROMETRY; PEPTIDES; SERUM ALBUMIN; SULFAMETHOXAZOLE;

EID: 67649992761     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900034r     Document Type: Article

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