The development of in vitro culture methods to characterize primary t-cell responses to drugs

Toxicological Sciences

Volumn 127, Issue 1, 2012, Pages 150-158

  Faulkner, Lee ^a   Martinsson, Klara ^a,b   Santoyo Castelazo, Anahi ^a   Cederbrant, Karin ^b   Schuppe Koistinen, Ina ^b   Powell, Helen ^b   Tugwood, Jonathan ^b   Naisbitt, D J ^a   Park, B Kevin ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Dendritic cells; Nitroso sulfamethoxazole; Primary T cells

Indexed keywords

ABACAVIR; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR3; DRUG METABOLITE; FLUCLOXACILLIN; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 5; LEUKOCYTE ANTIGEN; NITROSO SULFAMETHOXAZOLE; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG;

ALLELE; ALLERGENICITY; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CELL ASSAY; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; CULTURE TECHNIQUE; CYTOKINE RELEASE; DENDRITIC CELL; DOSE RESPONSE; DRUG RESPONSE; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNITY; IN VITRO STUDY; LYMPHOCYTE HOMING; MEMORY T LYMPHOCYTE; MODEL; MONOCYTE; NORMAL HUMAN; PHENOTYPE; PROTEIN EXPRESSION; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

EID: 84860188978     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs080     Document Type: Article

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