메뉴 건너뛰기




Volumn 23, Issue 1, 2010, Pages 184-192

Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINE; BENZENESULFONAMIDE DERIVATIVE; GLUTATHIONE; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROXYLAMINE; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; NITROSO DERIVATIVE; SULFADIAZINE; SULFAMETHOXAZOLE; SULFAPYRIDINE;

EID: 75149137515     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900329b     Document Type: Article
Times cited : (22)

References (66)
  • 2
    • 0035369825 scopus 로고    scopus 로고
    • Genetic susceptibility to adverse drug reactions
    • Pirmohamed, M., and Park, B. K. (2001) Genetic susceptibility to adverse drug reactions. Trends Pharmacol. Sci. 22, 298-305.
    • (2001) Trends Pharmacol. Sci , vol.22 , pp. 298-305
    • Pirmohamed, M.1    Park, B.K.2
  • 4
    • 59649084532 scopus 로고    scopus 로고
    • Clearing the MIST (metabolites in safety testing) of time: The impact of duration of administration on drug metabolite toxicity
    • Smith, D. A., Obach, R. S., Williams, D. P., and Park, B. K. (2009) Clearing the MIST (metabolites in safety testing) of time: The impact of duration of administration on drug metabolite toxicity. Chem.-Biol. Interact. 179, 60-67.
    • (2009) Chem.-Biol. Interact , vol.179 , pp. 60-67
    • Smith, D.A.1    Obach, R.S.2    Williams, D.P.3    Park, B.K.4
  • 5
    • 0142087834 scopus 로고    scopus 로고
    • Delayed drug hypersensitivity reactions
    • Pichler, W. J. (2003) Delayed drug hypersensitivity reactions. Ann. Intern. Med. 139, 683-693.
    • (2003) Ann. Intern. Med , vol.139 , pp. 683-693
    • Pichler, W.J.1
  • 6
    • 66149086597 scopus 로고    scopus 로고
    • The roles of drug metabolism in the pathogenesis of T-cell-mediated drug hypersensitivity
    • Lavergne, S. N., Park, B. K., and Naisbitt, D. J. (2008) The roles of drug metabolism in the pathogenesis of T-cell-mediated drug hypersensitivity. Curr. Opin. Allergy Clin. Immunol. 8, 299-307.
    • (2008) Curr. Opin. Allergy Clin. Immunol , vol.8 , pp. 299-307
    • Lavergne, S.N.1    Park, B.K.2    Naisbitt, D.J.3
  • 7
    • 34047103842 scopus 로고    scopus 로고
    • Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity
    • Wu, Y., Farrell, J., Pirmohamed, M., Park, B. K., and Naisbitt, D. J. (2007) Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity. J. Allergy Clin. Immunol. 119, 973-981.
    • (2007) J. Allergy Clin. Immunol , vol.119 , pp. 973-981
    • Wu, Y.1    Farrell, J.2    Pirmohamed, M.3    Park, B.K.4    Naisbitt, D.J.5
  • 8
    • 31944435105 scopus 로고    scopus 로고
    • Longlasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions
    • Beeler, A., Engler, O., Gerber, B. O., and Pichler, W. J. (2006) Longlasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions. J. Allergy Clin. Immunol. 117, 455-462.
    • (2006) J. Allergy Clin. Immunol , vol.117 , pp. 455-462
    • Beeler, A.1    Engler, O.2    Gerber, B.O.3    Pichler, W.J.4
  • 11
    • 0025118285 scopus 로고
    • An in vitro investigation of predisposition to sulphonamide idiosyncratic toxicity in dogs
    • Cribb, A. E., and Spielberg, S. P. (1990) An in vitro investigation of predisposition to sulphonamide idiosyncratic toxicity in dogs. Vet. Res. Commun. 14, 241-252.
    • (1990) Vet. Res. Commun , vol.14 , pp. 241-252
    • Cribb, A.E.1    Spielberg, S.P.2
  • 13
    • 23044473576 scopus 로고    scopus 로고
    • Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes
    • Roychowdhury, S., Vyas, P. M., Reilly, T. P., Gaspari, A. A., and Svensson, C. K. (2005) Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes. J. Pharmacol. Exp. Ther. 314, 43-52.
    • (2005) J. Pharmacol. Exp. Ther , vol.314 , pp. 43-52
    • Roychowdhury, S.1    Vyas, P.M.2    Reilly, T.P.3    Gaspari, A.A.4    Svensson, C.K.5
  • 15
    • 0030576307 scopus 로고    scopus 로고
    • Synthesis and reactions of nitroso sulfamethoxazole with biological nucleophiles - Implications for immune-mediated toxicity
    • Naisbitt, D. J., O'Neill, P. M., Pirmohamed, M., and Park, B. K. (1996) Synthesis and reactions of nitroso sulfamethoxazole with biological nucleophiles - Implications for immune-mediated toxicity. Bioorg. Med. Chem. Lett. 6, 1511-1516.
    • (1996) Bioorg. Med. Chem. Lett , vol.6 , pp. 1511-1516
    • Naisbitt, D.J.1    O'Neill, P.M.2    Pirmohamed, M.3    Park, B.K.4
  • 16
    • 0025947068 scopus 로고
    • Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity
    • Cribb, A. E., Miller, M., Leeder, J. S., Hill, J., and Spielberg, S. P. (1991) Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity. Drug Metab. Dispos. 19, 900-906.
    • (1991) Drug Metab. Dispos , vol.19 , pp. 900-906
    • Cribb, A.E.1    Miller, M.2    Leeder, J.S.3    Hill, J.4    Spielberg, S.P.5
  • 17
    • 0033001485 scopus 로고    scopus 로고
    • Cellular disposition of sulphamethoxazole and its metabolites: Implications for hypersensitivity
    • Naisbitt, D. J., Hough, S. J., Gill, H. J., Pirmohamed, M., Kitteringham, N. R., and Park, B. K. (1999) Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity. Br. J. Pharmacol. 126, 1393-1407.
    • (1999) Br. J. Pharmacol , vol.126 , pp. 1393-1407
    • Naisbitt, D.J.1    Hough, S.J.2    Gill, H.J.3    Pirmohamed, M.4    Kitteringham, N.R.5    Park, B.K.6
  • 19
    • 0036765861 scopus 로고    scopus 로고
    • Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation
    • Naisbitt, D. J., Farrell, J., Gordon, S. F., Maggs, J. L., Burkhart, C., Pichler, W. J., Pirmohamed, M., and Park, B. K. (2002) Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation. Mol. Pharmacol. 62, 628-637.
    • (2002) Mol. Pharmacol , vol.62 , pp. 628-637
    • Naisbitt, D.J.1    Farrell, J.2    Gordon, S.F.3    Maggs, J.L.4    Burkhart, C.5    Pichler, W.J.6    Pirmohamed, M.7    Park, B.K.8
  • 20
    • 44249117831 scopus 로고    scopus 로고
    • Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo
    • Cheng, L., Stewart, B. J., You, Q., Petersen, D. R., Ware, J. A., Piccotti, J. R., Kawabata, T. T., and Ju, C. (2008) Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo. Mol. Pharmacol. 73, 1769-1775.
    • (2008) Mol. Pharmacol , vol.73 , pp. 1769-1775
    • Cheng, L.1    Stewart, B.J.2    You, Q.3    Petersen, D.R.4    Ware, J.A.5    Piccotti, J.R.6    Kawabata, T.T.7    Ju, C.8
  • 21
    • 0028618807 scopus 로고
    • Immunochemical analysis of sulfonamide drug allergy: Identification of sulfamethoxazole-substituted human serum proteins
    • Meekins, C. V., Sullivan, T. J., and Gruchalla, R. S. (1994) Immunochemical analysis of sulfonamide drug allergy: Identification of sulfamethoxazole-substituted human serum proteins. J. Allergy Clin. Immunol. 94, 1017-1024.
    • (1994) J. Allergy Clin. Immunol , vol.94 , pp. 1017-1024
    • Meekins, C.V.1    Sullivan, T.J.2    Gruchalla, R.S.3
  • 22
    • 0031895436 scopus 로고    scopus 로고
    • Sulfonamide-induced reactions in desensitized patients with AIDSsThe role of covalent protein haptenation by sulfamethoxazole
    • Gruchalla, R. S., Pesenko, R. D., Do, T. T., and Skiest, D. J. (1998) Sulfonamide-induced reactions in desensitized patients with AIDSsThe role of covalent protein haptenation by sulfamethoxazole. J. Allergy Clin. Immunol. 101, 371-378.
    • (1998) J. Allergy Clin. Immunol , vol.101 , pp. 371-378
    • Gruchalla, R.S.1    Pesenko, R.D.2    Do, T.T.3    Skiest, D.J.4
  • 23
    • 67649992761 scopus 로고    scopus 로고
    • Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: Implications for hapten formation
    • Callan, H. E., Jenkins, R. E., Maggs, J. L., Lavergne, S. N., Clarke, S. E., Naisbitt, D. J., and Park, B. K. (2009) Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: Implications for hapten formation. Chem. Res. Toxicol. 22, 937-948.
    • (2009) Chem. Res. Toxicol , vol.22 , pp. 937-948
    • Callan, H.E.1    Jenkins, R.E.2    Maggs, J.L.3    Lavergne, S.N.4    Clarke, S.E.5    Naisbitt, D.J.6    Park, B.K.7
  • 24
    • 0029892271 scopus 로고    scopus 로고
    • Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection
    • Cribb, A. E., Nuss, C. E., Alberts, D. W., Lamphere, D. B., Grant, D. M., Grossman, S. J., and Spielberg, S. P. (1996) Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection. Chem. Res. Toxicol. 9, 500-507.
    • (1996) Chem. Res. Toxicol , vol.9 , pp. 500-507
    • Cribb, A.E.1    Nuss, C.E.2    Alberts, D.W.3    Lamphere, D.B.4    Grant, D.M.5    Grossman, S.J.6    Spielberg, S.P.7
  • 25
    • 0034980953 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of sulphamethoxazole: Demonstration of metabolismdependent haptenation and T-cell proliferation in vivo
    • Naisbitt, D. J., Gordon, S. F., Pirmohamed, M., Burkhart, C., Cribb, A. E., Pichler, W. J., and Park, B. K. (2001) Antigenicity and immunogenicity of sulphamethoxazole: Demonstration of metabolismdependent haptenation and T-cell proliferation in vivo. Br. J. Pharmacol. 133, 295-305.
    • (2001) Br. J. Pharmacol , vol.133 , pp. 295-305
    • Naisbitt, D.J.1    Gordon, S.F.2    Pirmohamed, M.3    Burkhart, C.4    Cribb, A.E.5    Pichler, W.J.6    Park, B.K.7
  • 26
    • 0036840668 scopus 로고    scopus 로고
    • Haptenation of sulfonamide reactive metabolites to cellular proteins
    • Manchanda, T., Hess, D., Dale, L., Ferguson, S. G., and Rieder, M. J. (2002) Haptenation of sulfonamide reactive metabolites to cellular proteins. Mol. Pharmacol. 62, 1011-1026.
    • (2002) Mol. Pharmacol , vol.62 , pp. 1011-1026
    • Manchanda, T.1    Hess, D.2    Dale, L.3    Ferguson, S.G.4    Rieder, M.J.5
  • 27
    • 0038340979 scopus 로고    scopus 로고
    • Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans
    • Farrell, J., Naisbitt, D. J., Drummond, N. S., Depta, J. P., Vilar, F. J., Pirmohamed, M., and Park, B. K. (2003) Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans. J. Pharmacol. Exp. Ther. 306, 229-237.
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , pp. 229-237
    • Farrell, J.1    Naisbitt, D.J.2    Drummond, N.S.3    Depta, J.P.4    Vilar, F.J.5    Pirmohamed, M.6    Park, B.K.7
  • 28
    • 0035826077 scopus 로고    scopus 로고
    • Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: Role of metabolites
    • Choquet-Kastylevsky, G., Santolaria, N., Tedone, R., Aujoulat, M., and Descotes, J. (2001) Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: Role of metabolites. Toxicol. Lett. 119, 183-192.
    • (2001) Toxicol. Lett , vol.119 , pp. 183-192
    • Choquet-Kastylevsky, G.1    Santolaria, N.2    Tedone, R.3    Aujoulat, M.4    Descotes, J.5
  • 29
    • 0035112838 scopus 로고    scopus 로고
    • Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole- metabolite-specific human CD4+ T-cells
    • Burkhart, C., von Greyerz, S., Depta, J. P., Naisbitt, D. J., Britschgi, M., Park, K. B., and Pichler, W. J. (2001) Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole- metabolite-specific human CD4+ T-cells. Br. J. Pharmacol. 132, 623-630.
    • (2001) Br. J. Pharmacol , vol.132 , pp. 623-630
    • Burkhart, C.1    von Greyerz, S.2    Depta, J.P.3    Naisbitt, D.J.4    Britschgi, M.5    Park, K.B.6    Pichler, W.J.7
  • 33
    • 39049150437 scopus 로고    scopus 로고
    • Allergies to sulfonamide antibiotics and sulfur-containing drugs
    • quiz 100-103, 111
    • Dibbern, D. A., Jr., and Montanaro, A. (2008) Allergies to sulfonamide antibiotics and sulfur-containing drugs. Ann. Allergy Asthma Immunol. 100, 91-100; quiz 100-103, 111.
    • (2008) Ann. Allergy Asthma Immunol , vol.100 , pp. 91-100
    • Dibbern Jr., D.A.1    Montanaro, A.2
  • 34
    • 37849012349 scopus 로고    scopus 로고
    • The sulfonamide group as a structural alert: A distorted story?
    • Smith, D. A., and Jones, R. M. (2008) The sulfonamide group as a structural alert: A distorted story? Curr. Opin. Drug Discovery Dev. 11, 72-79.
    • (2008) Curr. Opin. Drug Discovery Dev , vol.11 , pp. 72-79
    • Smith, D.A.1    Jones, R.M.2
  • 35
    • 34248339952 scopus 로고    scopus 로고
    • No proof of cross-reactivity between celecoxib and antibiotic sulfonamides
    • Smith, W. B., and Mullins, R. J. (2007) No proof of cross-reactivity between celecoxib and antibiotic sulfonamides. Intern. Med. J. 37, 347-348.
    • (2007) Intern. Med. J , vol.37 , pp. 347-348
    • Smith, W.B.1    Mullins, R.J.2
  • 37
    • 0032960782 scopus 로고    scopus 로고
    • Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones
    • von Greyerz, S., Zanni, M. P., Frutig, K., Schnyder, B., Burkhart, C., and Pichler, W. J. (1999) Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones. J. Immunol. 162, 595-602.
    • (1999) J. Immunol , vol.162 , pp. 595-602
    • von Greyerz, S.1    Zanni, M.P.2    Frutig, K.3    Schnyder, B.4    Burkhart, C.5    Pichler, W.J.6
  • 38
    • 33745261626 scopus 로고    scopus 로고
    • Transfection of drug-specific T-cell receptors into hybridoma cells: Tools to monitor drug interaction with T-cell receptors and evaluate cross-reactivity to related compounds
    • Schmid, D. A., Depta, J. P., Luthi, M., and Pichler, W. J. (2006) Transfection of drug-specific T-cell receptors into hybridoma cells: Tools to monitor drug interaction with T-cell receptors and evaluate cross-reactivity to related compounds. Mol. Pharmacol. 70, 356-365.
    • (2006) Mol. Pharmacol , vol.70 , pp. 356-365
    • Schmid, D.A.1    Depta, J.P.2    Luthi, M.3    Pichler, W.J.4
  • 39
    • 84986502806 scopus 로고
    • Catalytic reduction of nitroarenes with hydrazine hydrate in suitable solvents
    • Ayyangar, N. R., Lugade, A. G., Nikrad, P. V., and Sharma, V. K. (1981) Catalytic reduction of nitroarenes with hydrazine hydrate in suitable solvents. Synthesis 640.
    • (1981) Synthesis , pp. 640
    • Ayyangar, N.R.1    Lugade, A.G.2    Nikrad, P.V.3    Sharma, V.K.4
  • 40
    • 33845378909 scopus 로고
    • Heterogeneous catalytic transfer hydrogenation and its relation to other methods for reduction of organic compounds
    • Johnstone, R. A. W., Wilby, A. H., and Entwistle, I. D. (1985) Heterogeneous catalytic transfer hydrogenation and its relation to other methods for reduction of organic compounds. Chem. Rev. 85, 129-170.
    • (1985) Chem. Rev , vol.85 , pp. 129-170
    • Johnstone, R.A.W.1    Wilby, A.H.2    Entwistle, I.D.3
  • 41
    • 85082719810 scopus 로고
    • Facile transfer-reduction of nitroarenes to N-arylhydroxylamines with hydrazine in the presence of Raney-nickel
    • Ayyangar, N. R., Brahme, K. C., Kalkote, U. R., and Srinivasan, K. V. (1984) Facile transfer-reduction of nitroarenes to N-arylhydroxylamines with hydrazine in the presence of Raney-nickel. Synthesis 938-941.
    • (1984) Synthesis , pp. 938-941
    • Ayyangar, N.R.1    Brahme, K.C.2    Kalkote, U.R.3    Srinivasan, K.V.4
  • 42
    • 0000289571 scopus 로고
    • Rapid catalytic transfer reduction of aromatic nitro compounds to hydroxylamines
    • Entwistle, I. D., Gilkerson, T., Johnstone, R. A. W., and Telford, R. P. (1978) Rapid catalytic transfer reduction of aromatic nitro compounds to hydroxylamines. Tetrahedron 34, 213-215.
    • (1978) Tetrahedron , vol.34 , pp. 213-215
    • Entwistle, I.D.1    Gilkerson, T.2    Johnstone, R.A.W.3    Telford, R.P.4
  • 44
    • 0030576307 scopus 로고    scopus 로고
    • Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity
    • Naisbitt, D. J., O'Neill, P. M., Pirmohamed, M., and Park, K. B. (1996) Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity. Bioorg. Med. Chem. Lett. 6, 1511-1516.
    • (1996) Bioorg. Med. Chem. Lett , vol.6 , pp. 1511-1516
    • Naisbitt, D.J.1    O'Neill, P.M.2    Pirmohamed, M.3    Park, K.B.4
  • 45
    • 3543110157 scopus 로고    scopus 로고
    • Preparations of C-nitroso compounds
    • Gowenlock, B. G., and Richter-Addo, G. B. (2004) Preparations of C-nitroso compounds. Chem. Rev. 104, 3315-3340.
    • (2004) Chem. Rev , vol.104 , pp. 3315-3340
    • Gowenlock, B.G.1    Richter-Addo, G.B.2
  • 46
    • 0029060517 scopus 로고
    • Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine
    • Mauri-Hellweg, D., Bettens, F., Mauri, D., Brander, C., Hunziker, T., and Pichler, W. J. (1995) Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine. J. Immunol. 155, 462-472.
    • (1995) J. Immunol , vol.155 , pp. 462-472
    • Mauri-Hellweg, D.1    Bettens, F.2    Mauri, D.3    Brander, C.4    Hunziker, T.5    Pichler, W.J.6
  • 49
    • 84973718396 scopus 로고
    • Studies on the sensitization of animals with simple chemical compounds
    • Landsteiner, K., and Jacobs, J. (1935) Studies on the sensitization of animals with simple chemical compounds. J. Exp. Med. 61, 643-656.
    • (1935) J. Exp. Med , vol.61 , pp. 643-656
    • Landsteiner, K.1    Jacobs, J.2
  • 50
    • 0031719374 scopus 로고    scopus 로고
    • Role of drug disposition in drug hypersensitivity: A chemical, molecular and clinical perspective
    • Park, B. K., Pirmohamed, M., and Kitteringham, N. R. (1998) Role of drug disposition in drug hypersensitivity: A chemical, molecular and clinical perspective. Chem. Res. Toxicol. 9, 969-988.
    • (1998) Chem. Res. Toxicol , vol.9 , pp. 969-988
    • Park, B.K.1    Pirmohamed, M.2    Kitteringham, N.R.3
  • 51
    • 0037058248 scopus 로고    scopus 로고
    • Novel non-labile covalent binding of sulfamethoxazole reactive metabolites to cultured human lymphoid cells
    • Summan, M., and Cribb, A. E. (2002) Novel non-labile covalent binding of sulfamethoxazole reactive metabolites to cultured human lymphoid cells. Chem.-Biol. Interact. 142, 155-173.
    • (2002) Chem.-Biol. Interact , vol.142 , pp. 155-173
    • Summan, M.1    Cribb, A.E.2
  • 52
    • 1542285424 scopus 로고    scopus 로고
    • A chemically inert drug can stimulate T cells in vitro by their T cell receptor in non-sensitised individuals
    • Engler, O. B., Strasser, I., Naisbitt, D. J., Cerny, A., and Pichler, W. J. (2004) A chemically inert drug can stimulate T cells in vitro by their T cell receptor in non-sensitised individuals. Toxicology 197, 47-56.
    • (2004) Toxicology , vol.197 , pp. 47-56
    • Engler, O.B.1    Strasser, I.2    Naisbitt, D.J.3    Cerny, A.4    Pichler, W.J.5
  • 53
    • 33644892247 scopus 로고    scopus 로고
    • Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis
    • McLeod, R., Khan, A. R., Noble, G. A., Latkany, P., Jalbrzikowski, J., and Boyer, K. (2006) Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. Pediatr. Infect. Dis. J. 25, 270-272.
    • (2006) Pediatr. Infect. Dis. J , vol.25 , pp. 270-272
    • McLeod, R.1    Khan, A.R.2    Noble, G.A.3    Latkany, P.4    Jalbrzikowski, J.5    Boyer, K.6
  • 54
    • 22344449264 scopus 로고    scopus 로고
    • Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism
    • Winter, H. R., and Unadkat, J. D. (2005) Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism. Drug Metab. Dispos. 33, 969-976.
    • (2005) Drug Metab. Dispos , vol.33 , pp. 969-976
    • Winter, H.R.1    Unadkat, J.D.2
  • 55
    • 0025734129 scopus 로고
    • Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes
    • Pirmohamed, M., Coleman, M. D., Hussain, F., Breckenridge, A. M., and Park, B. K. (1991) Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes. Br. J. Clin. Pharmacol. 32, 303-310.
    • (1991) Br. J. Clin. Pharmacol , vol.32 , pp. 303-310
    • Pirmohamed, M.1    Coleman, M.D.2    Hussain, F.3    Breckenridge, A.M.4    Park, B.K.5
  • 56
    • 0032520749 scopus 로고    scopus 로고
    • Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone
    • Reilly, T. P., Bellevue, F. H., 3rd, Woster, P. M., and Svensson, C. K. (1998) Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone. Biochem. Pharmacol. 55, 803-810.
    • (1998) Biochem. Pharmacol , vol.55 , pp. 803-810
    • Reilly, T.P.1    Bellevue 3rd, F.H.2    Woster, P.M.3    Svensson, C.K.4
  • 57
    • 0025734129 scopus 로고
    • Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes
    • Pirmohamed, M., Coleman, M. D., Hussain, F., Breckenridge, A. M., and Park, B. K. (1991) Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes. Br. J. Clin. Pharmacol. 32, 303-310.
    • (1991) Br. J. Clin. Pharmacol , vol.32 , pp. 303-310
    • Pirmohamed, M.1    Coleman, M.D.2    Hussain, F.3    Breckenridge, A.M.4    Park, B.K.5
  • 58
    • 0023846286 scopus 로고
    • Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides
    • Rieder, M. J., Uetrecht, J., Shear, N. H., and Spielberg, S. P. (1988) Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides. J. Pharmacol. Exp. Ther. 244, 724-728.
    • (1988) J. Pharmacol. Exp. Ther , vol.244 , pp. 724-728
    • Rieder, M.J.1    Uetrecht, J.2    Shear, N.H.3    Spielberg, S.P.4
  • 59
  • 60
    • 0029879648 scopus 로고    scopus 로고
    • Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers
    • Mitra, A. K., Thummel, K. E., Kalhorn, T. F., Kharasch, E. D., Unadkat, J. D., and Slattery, J. T. (1996) Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers. Clin. Pharmacol. Ther. 59, 332-340.
    • (1996) Clin. Pharmacol. Ther , vol.59 , pp. 332-340
    • Mitra, A.K.1    Thummel, K.E.2    Kalhorn, T.F.3    Kharasch, E.D.4    Unadkat, J.D.5    Slattery, J.T.6
  • 61
    • 0029836423 scopus 로고    scopus 로고
    • The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole
    • Gill, H. J., Maggs, J. L., Madden, S., Pirmohamed, M., and Park, B. K. (1996) The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole. Br. J. Clin. Pharmacol. 42, 347-353.
    • (1996) Br. J. Clin. Pharmacol , vol.42 , pp. 347-353
    • Gill, H.J.1    Maggs, J.L.2    Madden, S.3    Pirmohamed, M.4    Park, B.K.5
  • 62
    • 0036888288 scopus 로고    scopus 로고
    • Cytokine fingerprinting of chemical allergens: Species comparisons and statistical analyses
    • Dearman, R. J., Warbrick, E. V., Skinner, R., and Kimber, I. (2002) Cytokine fingerprinting of chemical allergens: Species comparisons and statistical analyses. Food Chem. Toxicol. 40, 1881-1892.
    • (2002) Food Chem. Toxicol , vol.40 , pp. 1881-1892
    • Dearman, R.J.1    Warbrick, E.V.2    Skinner, R.3    Kimber, I.4
  • 63
    • 0029950454 scopus 로고    scopus 로고
    • Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens
    • Dearman, R. J., Moussavi, A., Kemeny, D. M., and Kimber, I. (1996) Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens. Immunology 89, 502-510.
    • (1996) Immunology , vol.89 , pp. 502-510
    • Dearman, R.J.1    Moussavi, A.2    Kemeny, D.M.3    Kimber, I.4
  • 64
    • 4544328132 scopus 로고    scopus 로고
    • Requirements for Th1-dependent immunity against infection with Leishmania major
    • von Stebut, E., and Udey, M. C. (2004) Requirements for Th1-dependent immunity against infection with Leishmania major. Microbes Infect. 6, 1102-1109.
    • (2004) Microbes Infect , vol.6 , pp. 1102-1109
    • von Stebut, E.1    Udey, M.C.2
  • 65
    • 10044277088 scopus 로고    scopus 로고
    • Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells
    • Hopkins, J. E., Naisbitt, D. J., Humphreys, N., Dearman, R. J., Kimber, I., and Park, B. K. (2005) Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells. Toxicology 206, 221-231.
    • (2005) Toxicology , vol.206 , pp. 221-231
    • Hopkins, J.E.1    Naisbitt, D.J.2    Humphreys, N.3    Dearman, R.J.4    Kimber, I.5    Park, B.K.6
  • 66
    • 68949205913 scopus 로고    scopus 로고
    • Drug-specific in vitro release of IL-2, IL-5, IL-13 and IFN-gamma in patients with delayed-type drug hypersensitivity
    • Lochmatter, P., Beeler, A., Kawabata, T. T., Gerber, B. O., and Pichler, W. J. (2009) Drug-specific in vitro release of IL-2, IL-5, IL-13 and IFN-gamma in patients with delayed-type drug hypersensitivity. Allergy 64, 1269-1278.
    • (2009) Allergy , vol.64 , pp. 1269-1278
    • Lochmatter, P.1    Beeler, A.2    Kawabata, T.T.3    Gerber, B.O.4    Pichler, W.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.