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Volumn 59, Issue 8, 2004, Pages 809-820

The lymphocyte transformation test in the diagnosis of drug hypersensitivity

Author keywords

Drug hypersensitivity; Lymphocyte transformation test; T cells

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; BETA LACTAM; CARBAMAZEPINE; CELECOXIB; CIPROFLOXACIN; CORTICOSTEROID; DICLOFENAC; DIURETIC AGENT; EDETIC ACID; HEPARIN; IMMUNOSUPPRESSIVE AGENT; LAMOTRIGINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; MACROLIDE; MEPIVACAINE; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PHENOBARBITAL; PHENYTOIN; PREDNISONE; QUINOLONE; SULFAMETHOXAZOLE; SULFONAMIDE; UNINDEXED DRUG; VITAMIN;

EID: 3442876477     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2004.00547.x     Document Type: Review
Times cited : (556)

References (48)
  • 2
    • 0142087834 scopus 로고    scopus 로고
    • Delayed drug hypersensitivity reactions
    • PICHLER WJ, Delayed drug hypersensitivity reactions. Ann Intern Med 2003;139:683-693.
    • (2003) Ann Intern Med , vol.139 , pp. 683-693
    • Pichler, W.J.1
  • 4
    • 0034529448 scopus 로고    scopus 로고
    • Immunological principles of adverse drug reactions: The initiation and propagation of immune responses elicited by drug treatment
    • NAISBITT DJ, GORDON SF, PIRMOHAMED M, PARK BK. Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment. Drug Saf 2000;23:483-507.
    • (2000) Drug Saf , vol.23 , pp. 483-507
    • Naisbitt, D.J.1    Gordon, S.F.2    Pirmohamed, M.3    Park, B.K.4
  • 5
    • 0027258555 scopus 로고
    • Selective generation of CD8+ T-cell clones from the peripheral blood of patients with cutaneous reactions to beta-lactam antibiotics
    • HERTL M, GEISEL J, BOECKER C, MERK HF. Selective generation of CD8+ T-cell clones from the peripheral blood of patients with cutaneous reactions to beta-lactam antibiotics. Br J Dermatol 1993;128:619-626.
    • (1993) Br J Dermatol , vol.128 , pp. 619-626
    • Hertl, M.1    Geisel, J.2    Boecker, C.3    Merk, H.F.4
  • 8
    • 0031772156 scopus 로고    scopus 로고
    • T-cell-mediated cytotoxicity against keratinocytcs in sulfamethoxazol-induced skin reaction
    • SCHNYDER B, FRUTIG K, MAURI-HELLWEG D, LIMAT A, PICHLER WJ. T-cell-mediated cytotoxicity against keratinocytcs in sulfamethoxazol-induced skin reaction. Clin Exp Allergy 1998;28:1412-1417.
    • (1998) Clin Exp Allergy , vol.28 , pp. 1412-1417
    • Schnyder, B.1    Frutig, K.2    Mauri-Hellweg, D.3    Limat, A.4    Pichler, W.J.5
  • 9
    • 1842290330 scopus 로고    scopus 로고
    • Role of delayed cellular hypersensitivity and adhesion molecules in amoxicillin-induced morbilliform rashes
    • BARBAUD AM, BENE MC, SCHMUTZ JL, EHLINGER A, WEBER M, FAURE GC. Role of delayed cellular hypersensitivity and adhesion molecules in amoxicillin-induced morbilliform rashes. Arch Dermatol 1997;133:481-486.
    • (1997) Arch Dermatol , vol.133 , pp. 481-486
    • Barbaud, A.M.1    Bene, M.C.2    Schmutz, J.L.3    Ehlinger, A.4    Weber, M.5    Faure, G.C.6
  • 10
    • 0033792579 scopus 로고    scopus 로고
    • Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction
    • POSADAS SJ, LEYVA L, TORRES MJ, RODRIGUEZ JL, BRAVO I, ROSAL M et al. Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction. J Allergy Clin Immunol 2000;106:769-776.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 769-776
    • Posadas, S.J.1    Leyva, L.2    Torres, M.J.3    Rodriguez, J.L.4    Bravo, I.5    Rosal, M.6
  • 11
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • ROMAGNAW S. The Th1/Th2 paradigm. Immunol Today 1997;18:263-266.
    • (1997) Immunol Today , vol.18 , pp. 263-266
    • Romagnaw, S.1
  • 12
    • 0034538071 scopus 로고    scopus 로고
    • Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions
    • YAWALKAR N, SHIRIKHADE M, HARI Y, NIEVERGELT, BRAATHEN LR, PICHLER WJ. Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions. J Allergy Clin Immunol 2000;106:1171-1176.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 1171-1176
    • Yawalkar, N.1    Shirikhade, M.2    Hari, Y.3    Nievergelt4    Braathen, L.R.5    Pichler, W.J.6
  • 14
    • 0031719374 scopus 로고    scopus 로고
    • Role of drug disposition in drug hypersensitivity: A chemical, molecular, and clinical perspective
    • PARK BK, PIRMOHAMED M, KITTERINGHAM NR. Role of drug disposition in drug hypersensitivity: a chemical, molecular, and clinical perspective. Chem Res Toxicol 1998;11:969-988.
    • (1998) Chem Res Toxicol , vol.11 , pp. 969-988
    • Park, B.K.1    Pirmohamed, M.2    Kitteringham, N.R.3
  • 15
    • 0022969542 scopus 로고
    • T-cell reactivity to penicillin. Phenotypic analysis of in vitro activated cell subsets
    • KOPONEN M, PICHLER WJ, de WECK AL. T-cell reactivity to penicillin. Phenotypic analysis of in vitro activated cell subsets. J Allergy Clin Immunol 1986;78:645-652.
    • (1986) J Allergy Clin Immunol , vol.78 , pp. 645-652
    • Koponen, M.1    Pichler, W.J.2    De Weck, A.L.3
  • 16
    • 0029060517 scopus 로고
    • Activation of drug specific CD4+ and CD8+ T-cells in individuals allergic to sulfonamides, phenytoin and carbamazepine
    • MAURI-HELLWEG D, BETTENS F, MAURI D, BRANDER C, HUNZIKER T, PICHLER WJ. Activation of drug specific CD4+ and CD8+ T-cells in individuals allergic to sulfonamides, phenytoin and carbamazepine. J Immunol 1995;155:462-472.
    • (1995) J Immunol , vol.155 , pp. 462-472
    • Mauri-Hellweg, D.1    Bettens, F.2    Mauri, D.3    Brander, C.4    Hunziker, T.5    Pichler, W.J.6
  • 17
    • 0029068773 scopus 로고
    • Heterogeneous T-cell responses to β-lactam-modified self-structures are observed in penicillin-allergic individuals
    • BRANDER C, MAURI-HELLWEG D, BETTENS F, ROLLI HP, GOLDMAN M, PICHLER WJ. Heterogeneous T-cell responses to β-lactam-modified self-structures are observed in penicillin-allergic individuals. J Immunol 1995;55:2670-2678.
    • (1995) J Immunol , vol.55 , pp. 2670-2678
    • Brander, C.1    Mauri-Hellweg, D.2    Bettens, F.3    Rolli, H.P.4    Goldman, M.5    Pichler, W.J.6
  • 19
    • 0030822702 scopus 로고    scopus 로고
    • Direct, MHC-dependent presentation of the drug sulfamethoxazol to human T-cell clones
    • SCHNYDER B, MAURI-HELLWEG D, ZANNI M, BETTENS F, PICHLER WJ. Direct, MHC-dependent presentation of the drug sulfamethoxazol to human T-cell clones. J Clin Invest 1997;100:136-141.
    • (1997) J Clin Invest , vol.100 , pp. 136-141
    • Schnyder, B.1    Mauri-Hellweg, D.2    Zanni, M.3    Bettens, F.4    Pichler, W.J.5
  • 20
    • 0032532378 scopus 로고    scopus 로고
    • HLA-restricted, processing- And metabolism-independent pathway of drug recognition by human αβ T lymphocytes
    • ZANNI MP, von GREVERZ S, SCHNYDER B, BRANDES KS, FRITIG K, HARI Y et al. HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human αβ T lymphocytes. J Clin Invest 1998;102:1591-1598.
    • (1998) J Clin Invest , vol.102 , pp. 1591-1598
    • Zanni, M.P.1    Von Greverz, S.2    Schnyder, B.3    Brandes, K.S.4    Fritig, K.5    Hari, Y.6
  • 21
    • 0036676978 scopus 로고    scopus 로고
    • Pharmacological interaction of drugs with antigen-specific immune receptors: The p-i concept
    • PICHLER WJ. Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept. Curr Opin Allergy Clin Immunol 2002;2:301-305.
    • (2002) Curr Opin Allergy Clin Immunol , vol.2 , pp. 301-305
    • Pichler, W.J.1
  • 22
    • 0035681563 scopus 로고    scopus 로고
    • Guidelines for performing skin tests with drugs in the investigation of cutaneous adverse drug reactions
    • European Society of Contact Dermatitis
    • BARBAUD A, GONCALO M, BRUYNZEEL D, BIRCHER A. European Society of Contact Dermatitis. Guidelines for performing skin tests with drugs in the investigation of cutaneous adverse drug reactions. Contact Dermatitis 2001;45;321-328.
    • (2001) Contact Dermatitis , vol.45 , pp. 321-328
    • Barbaud, A.1    Goncalo, M.2    Bruynzeel, D.3    Bircher, A.4
  • 23
    • 0031949018 scopus 로고    scopus 로고
    • Immunocompeten T-cells and adhesion molecules in 14 cases of cutaneous drug reactions induced with the use of antibiotics
    • BARBAUD AM, BENE MC, REICHERT-PENETRAT S, JACQUIN-PETIT MA, SCHMUTZ JL, FAURE GC. Immunocompeten T-cells and adhesion molecules in 14 cases of cutaneous drug reactions induced with the use of antibiotics. Arch Dermatol 1998;134:1040-1041.
    • (1998) Arch Dermatol , vol.134 , pp. 1040-1041
    • Barbaud, A.M.1    Bene, M.C.2    Reichert-Penetrat, S.3    Jacquin-Petit, M.A.4    Schmutz, J.L.5    Faure, G.C.6
  • 24
    • 0033774505 scopus 로고    scopus 로고
    • T-cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug-specific and cytotoxic
    • YAWALKAR N, HARI Y, FRUTIG K, EGLI F, WENDLAND T, BRAATHEN L et al. T-cells isolated from positive epicutaneous test reactions to amoxicillin and ceftriaxone are drug-specific and cytotoxic. J Invest Dermatol 2000;115:647-652.
    • (2000) J Invest Dermatol , vol.115 , pp. 647-652
    • Yawalkar, N.1    Hari, Y.2    Frutig, K.3    Egli, F.4    Wendland, T.5    Braathen, L.6
  • 28
    • 0035999867 scopus 로고    scopus 로고
    • Determination of interleukin-5 secretion from drug-specific activated ex vivo peripheral blood mononuclear cells as a test system for the in vitro detection of drug sensitisation
    • SACHS B, ERDMANN S, MALTE BARON J, NEIS M, AL MASAOUDI T, MERK HF. Determination of interleukin-5 secretion from drug-specific activated ex vivo peripheral blood mononuclear cells as a test system for the in vitro detection of drug sensitisation. Clin Exp Allergy 2002;32:736-744.
    • (2002) Clin Exp Allergy , vol.32 , pp. 736-744
    • Sachs, B.1    Erdmann, S.2    Malte Baron, J.3    Neis, M.4    Al Masaoudi, T.5    Merk, H.F.6
  • 29
    • 0036899105 scopus 로고    scopus 로고
    • Acute generalized exanthematous pustulosis: Role of cytotoxic T-cells in pustule formation
    • SCHMID S, KUECHLER PC, BRITSCHGI M, STEINER UC, YAWALKAR N, LIMAT A et al. Acute generalized exanthematous pustulosis: role of cytotoxic T-cells in pustule formation. Am J Pathology 2002;161:2079-2086.
    • (2002) Am J Pathology , vol.161 , pp. 2079-2086
    • Schmid, S.1    Kuechler, P.C.2    Britschgi, M.3    Steiner, U.C.4    Yawalkar, N.5    Limat, A.6
  • 30
    • 0028918534 scopus 로고
    • CD8+ dermal T-cells from a sulphamethoxazole-induced bullous exanthem proliferate in response to drug-modified liver microsomes
    • HERTL M, JUGERT F, MERK HF. CD8+ dermal T-cells from a sulphamethoxazole-induced bullous exanthem proliferate in response to drug-modified liver microsomes. Br J Dermatol 1995;132:215-220.
    • (1995) Br J Dermatol , vol.132 , pp. 215-220
    • Hertl, M.1    Jugert, F.2    Merk, H.F.3
  • 31
    • 0020625891 scopus 로고
    • Lymphokine regulation of activated (Gl) lymphocytes: I. Prostaglandin E2-induced inhibition of interleukin 2 production
    • WALKER C, KRISTENSEN F, BETTENS F, DEWECK AL. Lymphokine regulation of activated (Gl) lymphocytes: I. Prostaglandin E2-induced inhibition of interleukin 2 production. J Immunol 1983;130:1770-1773.
    • (1983) J Immunol , vol.130 , pp. 1770-1773
    • Walker, C.1    Kristensen, F.2    Bettens, F.3    Deweck, A.L.4
  • 32
    • 0034984280 scopus 로고    scopus 로고
    • In vitro T-cel responses to beta-lactam drugs in immediate and nonimmediate allergic reactions
    • LUQUE I, LEYVA L, JOSE TORRES M, ROSAL M, MAYORGA C, SEGURA JM et al. In vitro T-cel responses to beta-lactam drugs in immediate and nonimmediate allergic reactions. Allergy 2001;56:611-618.
    • (2001) Allergy , vol.56 , pp. 611-618
    • Luque, I.1    Leyva, L.2    Jose Torres, M.3    Rosal, M.4    Mayorga, C.5    Segura, J.M.6
  • 34
    • 0344951264 scopus 로고    scopus 로고
    • Hypersensitivity reactions to carbamazepine: Characterization of the specificity, phenotype, and cytokine profile of drug-specific T-cell clones
    • NAISBITT DJ, BRITSCHGI M, WONG G, FARRELL J, DEPTA JPH, CHADWICK DW et al. Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T-cell clones. Mol Pharmacol 2003;63:732-741.
    • (2003) Mol Pharmacol , vol.63 , pp. 732-741
    • Naisbitt, D.J.1    Britschgi, M.2    Wong, G.3    Farrell, J.4    Depta, J.P.H.5    Chadwick, D.W.6
  • 35
    • 0034058155 scopus 로고    scopus 로고
    • Skin and laboratory tests in amoxicillin- and penicillin-induced morbilliform skin eruption
    • SCHNYDER B, PICHLER WJ. Skin and laboratory tests in amoxicillin- and penicillin-induced morbilliform skin eruption. Clin Exp Allergy 2000;30:590-595.
    • (2000) Clin Exp Allergy , vol.30 , pp. 590-595
    • Schnyder, B.1    Pichler, W.J.2
  • 36
    • 0042326178 scopus 로고    scopus 로고
    • For ENDA: The EAACI interest group on drug provocation testing in the diagnosis of drug hypersensitivity reactions: General considerations
    • ABERER W, BIRCHER A, ROMANO A, BLANCA M, CAMPI P, FERNANDEZ J et al. For ENDA: the EAACI interest group on drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations. Allergy 2003;58:854-886.
    • (2003) Allergy , vol.58 , pp. 854-886
    • Aberer, W.1    Bircher, A.2    Romano, A.3    Blanca, M.4    Campi, P.5    Fernandez, J.6
  • 37
    • 0028816834 scopus 로고
    • Prevalence of atopy and pollinosis in the adult population of Switzerland (SAPALDIA study). Swiss Study on Air Pollution and Lung Diseases in Adults
    • WUTHRICH B, SCHINDLER C, LEUENBERGER P, ACKERMANN-LIEBRICH U. Prevalence of atopy and pollinosis in the adult population of Switzerland (SAPALDIA study). Swiss Study on Air Pollution and Lung Diseases in Adults. Int Arch Allergy Immunol 1995;106:149-156.
    • (1995) Int Arch Allergy Immunol , vol.106 , pp. 149-156
    • Wuthrich, B.1    Schindler, C.2    Leuenberger, P.3    Ackermann-Liebrich, U.4
  • 38
    • 0031050054 scopus 로고    scopus 로고
    • The lymphocyte transformation test for the diagnosis of drug allergy: Sensitivity and specificity
    • NYFELER B, PICHLER WJ. The lymphocyte transformation test for the diagnosis of drug allergy: sensitivity and specificity. Clin Exp Allergy 1997;27:175-181.
    • (1997) Clin Exp Allergy , vol.27 , pp. 175-181
    • Nyfeler, B.1    Pichler, W.J.2
  • 39
    • 0036279452 scopus 로고    scopus 로고
    • Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones
    • SIEBEN S, KAWAKUBO Y, AL MASAOUDI T, MERK HF, BLOMEKE B. Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. J Allergy Clin Immunol 2002;109:1005-1011.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 1005-1011
    • Sieben, S.1    Kawakubo, Y.2    Al Masaoudi, T.3    Merk, H.F.4    Blomeke, B.5
  • 40
    • 0037045073 scopus 로고    scopus 로고
    • Utility of patch testing in patients with hypersensitivity syndromes associated with abacavir
    • PHILLIPS EJ, SULLIVAN JR, KNOWLES SR, SHEAR NH. Utility of patch testing in patients with hypersensitivity syndromes associated with abacavir. AIDS 2002;16:2223-2225.
    • (2002) AIDS , vol.16 , pp. 2223-2225
    • Phillips, E.J.1    Sullivan, J.R.2    Knowles, S.R.3    Shear, N.H.4
  • 45
    • 9844252868 scopus 로고    scopus 로고
    • Diagnostic value of specific T-cell reactivity to drugs in 95 cases of drug induced liver injury
    • MARIA VA, VICTORINO RM. Diagnostic value of specific T-cell reactivity to drugs in 95 cases of drug induced liver injury. Gut 1997;41:534-540.
    • (1997) Gut , vol.41 , pp. 534-540
    • Maria, V.A.1    Victorino, R.M.2
  • 47
    • 0033601902 scopus 로고    scopus 로고
    • Lymphocyte transformation test for the evaluation of adverse effects of antituberculous drugs
    • SCHREIBER J, ZISSEL G, GREINERT U, SCHLAAK M, MULLER-QUERNHEIM J. Lymphocyte transformation test for the evaluation of adverse effects of antituberculous drugs. Eur J Med Res 1999;4:67-71.
    • (1999) Eur J Med Res , vol.4 , pp. 67-71
    • Schreiber, J.1    Zissel, G.2    Greinert, U.3    Schlaak, M.4    Muller-Quernheim, J.5


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