A chemically inert drug can stimulate T cells in vitro by their T cell receptor in non-sensitised individuals

Toxicology

Volumn 197, Issue 1, 2004, Pages 47-56

  Engler, Olivier B ^a   Strasser, Ingrid ^a   Naisbitt, Dean J ^b   Cerny, Andreas ^c   Pichler, Werner J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c Ospedale Civico Lugano   (Switzerland)

Author keywords

Allergy; Drug; Immunmodulation; Inert; Sulfamethoxazole; Sulfamethoxazole nitroso; T cells

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; DRUG METABOLITE; INTERLEUKIN 2; SULFAMETHOXAZOLE; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; BLOOD; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EXPOSURE; DRUG MECHANISM; HEALTH STATUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MALE; MOLECULAR CLONING; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIZATION; T LYMPHOCYTE ACTIVATION;

ADJUVANTS, IMMUNOLOGIC; ADULT; ANTI-INFECTIVE AGENTS; ANTIGEN-PRESENTING CELLS; CELL DIVISION; CELL LINE; CLONE CELLS; CYTOKINES; CYTOTOXICITY TESTS, IMMUNOLOGIC; HUMANS; MALE; NITROSO COMPOUNDS; RECEPTORS, ANTIGEN, T-CELL; SULFAMETHOXAZOLE; T-LYMPHOCYTES;

EID: 1542285424     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2003.12.008     Document Type: Article

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