In vitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test

Clinical and Experimental Allergy

Volumn 43, Issue 9, 2013, Pages 1027-1037

  Porebski, G ^a,b,c   Pecaric Petkovic, T ^a,b   Groux Keller, M ^a,b   Bosak, M ^c   Kawabata, T T ^d   Pichler, W J ^a,b  

^a ADR AC GmbH   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^d PFIZER INC   (United States)

Author keywords

Cytokines; Granulysin; Granzyme B; Lymophocyte transformation test; Stevens Johnson syndrome; Toxic epidermal necrolysis

Indexed keywords

ALLOPURINOL; CARBAMAZEPINE; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; GRANULYSIN; GRANZYME B; INTERLEUKIN 7; LAMOTRIGINE; MEFENAMIC ACID; OXIPURINOL; SULFONAMIDE;

ADULT; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG RESPONSE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMAN; IN VITRO STUDY; LYMPHOCYTE TRANSFORMATION TEST; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROVOCATION TEST; STEVENS JOHNSON SYNDROME; SUPERNATANT;

CYTOKINES; GRANULYSIN; GRANZYME B; LYMOPHOCYTE TRANSFORMATION TEST; STEVENS-JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS;

ADULT; AGED; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CYTOKINES; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; GRANZYMES; HUMANS; INTERLEUKIN-15; INTERLEUKIN-7; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MIDDLE AGED; ROC CURVE; STEVENS-JOHNSON SYNDROME; YOUNG ADULT;

EID: 84882775239     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12145     Document Type: Article

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