Interaction between ROS dependent DNA damage, mitochondria and p38 MAPK underlies senescence of human adult stem cells

Aging

Volumn 6, Issue 6, 2014, Pages 481-495

  Borodkina, Aleksandra ^a   Shatrova, Alla ^a   Abushik, Polina ^b   Nikolsky, Nikolay ^a,c   Burova, Elena ^a  

^a INSTITUTE OF CYTOLOGY   (Russian Federation)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^c PETER THE GREAT ST PETERSBURG POLYTECHNIC UNIVERSITY   (Russian Federation)

Author keywords

DDR; Mesenchymal stem cells; ROS; Senescence

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE;

ADULT STEM CELL; CELL AGING; CELL LINE; DNA DAMAGE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT STEM CELLS; BLOTTING, WESTERN; CELL AGING; CELL LINE; DNA DAMAGE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MESENCHYMAL STROMAL CELLS; MITOCHONDRIA; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84903449524     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100673     Document Type: Article

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