-
1
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
DOI 10.1038/nrm2233, PII NRM2233
-
Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007; 8:729-740. (Pubitemid 47312822)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
3
-
-
0035253719
-
Cellular senescence as a tumor-protection mechanism: The essential role of counting
-
DOI 10.1016/S0959-437X(00)00163-5
-
Wright WE, Shay JW. Cellular senescence as a tumor-protection mechanism: the essential role of counting. Curr Opin Genet Dev 2001; 11:98-103. (Pubitemid 32119285)
-
(2001)
Current Opinion in Genetics and Development
, vol.11
, Issue.1
, pp. 98-103
-
-
Wright, W.E.1
Shay, J.W.2
-
4
-
-
0036629255
-
Oxidative stress shortens telomeres
-
DOI 10.1016/S0968-0004(02)02110-2, PII S0968000402021102
-
von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 2002; 27:339-344. (Pubitemid 34756516)
-
(2002)
Trends in Biochemical Sciences
, vol.27
, Issue.7
, pp. 339-344
-
-
Von Zglinicki, T.1
-
5
-
-
0035545802
-
Putting the stress on senescence
-
DOI 10.1016/S0955-0674(00)00278-7
-
Serrano M, Blasco MA. Putting the stress on senescence. Curr Opin Cell Biol 2001; 13:748-753. (Pubitemid 33042736)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.6
, pp. 748-753
-
-
Serrano, M.1
Blasco, M.A.2
-
6
-
-
0036830475
-
From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing
-
DOI 10.1016/S1357-2725(02)00034-1, PII S1357272502000341
-
Toussaint O, Remacle J, Dierick JF et al. From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing. Int J Biochem Cell Biol 2002; 34:1415-1429. (Pubitemid 35245399)
-
(2002)
International Journal of Biochemistry and Cell Biology
, vol.34
, Issue.11
, pp. 1415-1429
-
-
Toussaint, O.1
Remacle, J.2
Dierick, J.-F.3
Pascal, T.4
Frippiat, C.5
Zdanov, S.6
Magalhaes, J.P.7
Royer, V.8
Chainiaux, F.9
-
7
-
-
37649016525
-
-
Nyström T, Osiewacz H, eds. Heidelberg: Springer-Verlag Berlin
-
Toussaint O, Salmon M, Royer V et al. In: Nyström T, Osiewacz H, eds. Topics in Current Genetics. Heidelberg: Springer-Verlag Berlin, 2003:3.
-
(2003)
Topics in Current Genetics
, vol.3
-
-
Toussaint, O.1
Salmon, M.2
Royer, V.3
-
8
-
-
0033732110
-
T-Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
-
Toussaint O, Medrano EE, von Zglinicki. T-Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Experimental Gerontology 2000; 35:927-945.
-
(2000)
Experimental Gerontology
, vol.35
, pp. 927-945
-
-
Toussaint, O.1
Medrano, E.E.2
Von, Zglinicki.3
-
9
-
-
0038013875
-
Senescence, apoptosis and therapy - Cutting the lifelines of cancer
-
Schmitt CA. Senescence, apoptosis and therapy-cutting the lifelines of cancer. Nat Rev Cancer 2003; 3:286-295. (Pubitemid 37328864)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.4
, pp. 286-295
-
-
Schmitt, C.A.1
-
10
-
-
5444229646
-
2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase
-
DOI 10.1016/j.exger.2004.06.004, PII S053155650400186X
-
2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. Experimental Gerontology 2004; 39:1379-1389. (Pubitemid 39360379)
-
(2004)
Experimental Gerontology
, vol.39
, Issue.9
, pp. 1379-1389
-
-
Pedro De Magalhaes, J.1
Chainiaux, F.2
De Longueville, F.3
Mainfroid, V.4
Migeot, V.5
Marcq, L.6
Remacle, J.7
Salmon, M.8
Toussaint, O.9
-
11
-
-
0031466618
-
Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart
-
Shiloh, Y. Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart. Annu Rev Genet 1997; 31:635-662.
-
(1997)
Annu Rev Genet
, vol.31
, pp. 635-662
-
-
Shiloh, Y.1
-
12
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
DOI 10.1038/nature02118
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003; 426:194-198. (Pubitemid 37442589)
-
(2003)
Nature
, vol.426
, Issue.6963
, pp. 194-198
-
-
D'Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
13
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
-
DOI 10.1038/nature01385
-
Wong KK, Maser RS, Bachoo RM et al. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 2003; 421:643-648. (Pubitemid 36227673)
-
(2003)
Nature
, vol.421
, Issue.6923
, pp. 643-648
-
-
Wong, K.-K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
14
-
-
0037125201
-
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts
-
DOI 10.1016/S0014-5793(02)02973-3, PII S0014579302029733
-
de Magalhaes JP, Chainiaux F, Remacle J et al. Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts. FEBS letters 2002; 523:157-162. (Pubitemid 34786078)
-
(2002)
FEBS Letters
, vol.523
, Issue.1-3
, pp. 157-162
-
-
De Magalhaes, J.P.1
Chainiaux, F.2
Remacle, J.3
Toussaint, O.4
-
15
-
-
0037064011
-
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis
-
DOI 10.1074/jbc.M202671200
-
Gorbunova V, Seluanov A, Pereira-Smith OM. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. The Journal of Biological Chemistry 2002; 277:38540-38549. (Pubitemid 35154713)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.41
, pp. 38540-38549
-
-
Gorbunova, V.1
Seluanov, A.2
Pereira-Smith, O.M.3
-
16
-
-
0346373567
-
Stress-induced Premature Senescence in hTERT-expressing Ataxia Telangiectasia Fibroblasts
-
DOI 10.1074/jbc.M309457200
-
Naka K, Tachibana A, Ikeda K et al. Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts. The Journal of Biological Chemistry 2004; 279:2030-2037. (Pubitemid 38084474)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 2030-2037
-
-
Naka, K.1
Tachibana, A.2
Ikeda, K.3
Motoyama, N.4
-
17
-
-
0345932931
-
Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway
-
DOI 10.1046/j.1365-2443.2003.00620.x
-
Iwasa H, Han J, Ishikawa F. Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells 2003; 8:131-144. (Pubitemid 36511698)
-
(2003)
Genes to Cells
, vol.8
, Issue.2
, pp. 131-144
-
-
Iwasa, H.1
Han, J.2
Ishikawa, F.3
-
18
-
-
0036242247
-
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
-
DOI 10.1128/MCB.22.10.3389-3403.2002
-
Wang W, Chen JX, Liao R et al. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol Cell Biol 2002; 22:3389-3403. (Pubitemid 34453979)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.10
, pp. 3389-3403
-
-
Wang, W.1
Chen, J.X.2
Liao, R.3
Deng, Q.4
Zhou, J.J.5
Huang, S.6
Sun, P.7
-
19
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
DOI 10.1038/ncb1024
-
Parrinello S, Samper E, Krtolica A et al. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol 2003; 5:741-747. (Pubitemid 36986782)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.8
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
20
-
-
0034682721
-
Cellular senescence: Mitotic clock or culture shock?
-
Sherr CJ, DePinho RA. Cellular senescence: mitotic clock or culture shock? Cell 2000; 102:407-410.
-
(2000)
Cell
, vol.102
, pp. 407-410
-
-
Sherr, C.J.1
Depinho, R.A.2
-
21
-
-
0033638915
-
The mammalian UV response: C-Jun induction is required for exit from p53-imposed growth arrest
-
Shaulian E, Schreiber M, Piu F et al. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 2000; 103:897-907.
-
(2000)
Cell
, vol.103
, pp. 897-907
-
-
Shaulian, E.1
Schreiber, M.2
Piu, F.3
-
22
-
-
0036731380
-
Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence
-
Haq R, Brenton JD, Takahashi M et al. Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence. Cancer Res 2002; 62:5076-5082. (Pubitemid 34987550)
-
(2002)
Cancer Research
, vol.62
, Issue.17
, pp. 5076-5082
-
-
Haq, R.1
Brenton, J.D.2
Takahashi, M.3
Finan, D.4
Rottapel, R.5
Zanke, B.6
-
23
-
-
0346463059
-
High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts
-
DOI 10.1074/jbc.M308644200
-
Deng Q, Liao R, Wu BL et al. High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts. The Journal of Biological Chemistry 2004; 279:1050-1059. (Pubitemid 38082626)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.2
, pp. 1050-1059
-
-
Deng, Q.1
Liao, R.2
Wu, B.-L.3
Sun, P.4
-
24
-
-
34547955129
-
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype
-
DOI 10.1016/j.exger.2007.04.009, PII S0531556507000897
-
Borlon C, Debacq-Chainiaux F, Hinrichs C et al. The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype. Experimental Gerontology 2007; 42:911-923. (Pubitemid 47268734)
-
(2007)
Experimental Gerontology
, vol.42
, Issue.9
, pp. 911-923
-
-
Borlon, C.1
Debacq-Chainiaux, F.2
Hinrichs, C.3
Scharffetter-Kochanek, K.4
Toussaint, O.5
Wlaschek, M.6
-
25
-
-
43249099271
-
Expression profiling of senescent-associated genes in human dermis from young and old donors
-
Borlon C, Weemaels G, Godard P et al. Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study. Biogerontology 2008; 9:197-208.
-
(2008)
Proof-of-concept Study. Biogerontology
, vol.9
, pp. 197-208
-
-
Borlon, C.1
Weemaels, G.2
Godard, P.3
-
26
-
-
41549095405
-
Role of TGF-beta1-independent changes in protein neosyn thesis, p38alphaMAPK and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis
-
Chretien A, Dierick JF, Delaive E et al. Role of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis. Free Radical Biology & Medicine 2008; 44:1732-1751.
-
(2008)
Free Radical Biology & Medicine
, vol.44
, pp. 1732-1751
-
-
Chretien, A.1
Dierick, J.F.2
Delaive, E.3
-
27
-
-
20144362952
-
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway
-
DOI 10.1242/jcs.01651
-
Debacq-Chainiaux F, Borlon C, Pascal T et al. Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway. J Cell Sci 2005; 118:743-758. (Pubitemid 40372583)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.4
, pp. 743-758
-
-
Debacq-Chainiaux, F.1
Borlon, C.2
Pascal, T.3
Royer, V.4
Eliaers, F.5
Ninane, N.6
Carrard, G.7
Friguet, B.8
De Longueville, F.9
Boffe, S.10
Remacle, J.11
Toussaint, O.12
-
28
-
-
0035951791
-
2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts
-
2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts. The Journal of Biological Chemistry 2001; 276:2531-2537.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 2531-2537
-
-
Frippiat, C.1
Chen, Q.M.2
Zdanov, S.3
-
29
-
-
40949121097
-
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration
-
Glotin AL, Debacq-Chainiaux F, Brossas JY et al. Prematurely senescent ARPE-19 cells display features of age-related macular degeneration. Free Radical Biology and Medicine 2008; 44:1348-1361.
-
(2008)
Free Radical Biology and Medicine
, vol.44
, pp. 1348-1361
-
-
Glotin, A.L.1
Debacq-Chainiaux, F.2
Brossas, J.Y.3
-
30
-
-
21244445454
-
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays
-
DOI 10.1016/j.febslet.2005.05.056, PII S0014579305006708
-
Pascal T, Debacq-Chainiaux F, Chretien A et al. Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays. FEBS Letters 2005; 579:3651-3659. (Pubitemid 40897706)
-
(2005)
FEBS Letters
, vol.579
, Issue.17
, pp. 3651-3659
-
-
Pascal, T.1
Debacq-Chainiaux, F.2
Chretien, A.3
Bastin, C.4
Dabee, A.-F.5
Bertholet, V.6
Remacle, J.7
Toussaint, O.8
-
31
-
-
42649106818
-
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts
-
Debacq-Chainiaux F, Pascal T, Boilan E et al. Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts. Free Radical Biology and Medicine 2008; 44:1817-1832.
-
(2008)
Free Radical Biology and Medicine
, vol.44
, pp. 1817-1832
-
-
Debacq-Chainiaux, F.1
Pascal, T.2
Boilan, E.3
-
32
-
-
0033578721
-
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression
-
Hanafusa H, Ninomiya-Tsuji J, Masuyama N et al. Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression. The Journal of Biological Chemistry 1999; 274:27161-27167.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 27161-27167
-
-
Hanafusa, H.1
Ninomiya-Tsuji, J.2
Masuyama, N.3
-
34
-
-
0029417335
-
2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1
-
2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1. The Journal of Biological Chemistry 1995; 270:30334-30338.
-
(1995)
The Journal of Biological Chemistry
, vol.270
, pp. 30334-30338
-
-
Thannickal, V.J.1
Fanburg, B.L.2
-
35
-
-
34547230349
-
Normal or stress-induced fibroblast senescence involves COX-2 activity
-
DOI 10.1016/j.yexcr.2007.04.033, PII S0014482707002157
-
Zdanov S, Bernard D, Debacq-Chainiaux F et al. Normal or stress-induced fibroblast senescence involves COX-2 activity. Experimental Cell Research 2007; 313:3046-3056. (Pubitemid 47125881)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.14
, pp. 3046-3056
-
-
Zdanov, S.1
Bernard, D.2
Debacq-Chainiaux, F.3
Martien, S.4
Gosselin, K.5
Vercamer, C.6
Chelli, F.7
Toussaint, O.8
Abbadie, C.9
-
36
-
-
67349102250
-
P53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O 2)-induced premature senescence of human fibroblasts
-
Zdanov S, Toussaint O, Debacq-Chainiaux F. p53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O (2)-induced premature senescence of human fibroblasts. Biogerontology 2009; 10:291-298.
-
(2009)
Biogerontology
, vol.10
, pp. 291-298
-
-
Zdanov, S.1
Toussaint, O.2
Debacq-Chainiaux, F.3
-
37
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
-
Bulavin DV, Saito S, Hollander MC et al. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J 1999; 18:6845-6854.
-
(1999)
EMBO J
, vol.18
, pp. 6845-6854
-
-
Bulavin, D.V.1
Saito, S.2
Hollander, M.C.3
-
39
-
-
0033617288
-
P38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389
-
Huang C, Ma WY, Maxiner A et al. p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389. The Journal of Biological Chemistry 1999; 274:12229-12235.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 12229-12235
-
-
Huang, C.1
Ma, W.Y.2
Maxiner, A.3
-
40
-
-
0034595817
-
Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase
-
DOI 10.1074/jbc.M000312200
-
Sayed M, Kim SO, Salh BS et al. Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase. The Journal of Biological Chemistry 2000; 275:16569-16573. (Pubitemid 30398881)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.22
, pp. 16569-16573
-
-
Sayed, M.1
Kim, S.O.2
Salh, B.S.3
Issinger, O.-G.4
Pelech, S.L.5
-
41
-
-
0036803602
-
In the cellular garden of forking paths: How p38 MAPKs signal for downstream assistance
-
DOI 10.1515/BC.2002.173
-
Shi Y, Gaestel M. In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance. Biol Chem 2002; 383:1519-1536. (Pubitemid 35282972)
-
(2002)
Biological Chemistry
, vol.383
, Issue.10
, pp. 1519-1536
-
-
Shi, Y.1
Gaestel, M.2
-
42
-
-
0036613212
-
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
-
Bulavin DV, Demidov ON, Saito S et al. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity. Nat Genet 2002; 31:210-215.
-
(2002)
Nat Genet
, vol.31
, pp. 210-215
-
-
Bulavin, D.V.1
Demidov, O.N.2
Saito, S.3
-
43
-
-
16244403047
-
Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells
-
Park JS, Kim HY, Kim HW et al. Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells. Mechanisms of Ageing and Development 2005; 126:551-559.
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, pp. 551-559
-
-
Park, J.S.1
Kim, H.Y.2
Kim, H.W.3
-
44
-
-
4744371424
-
Morphological adjustment of senescent cells by modulating caveolin-1 status
-
DOI 10.1074/jbc.M402352200
-
Cho KA, Ryu SJ, Oh YS et al. Morphological adjustment of senescent cells by modulating caveolin-1 status. The Journal of Biological Chemistry 2004; 279:42270-42278. (Pubitemid 39313676)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.40
, pp. 42270-42278
-
-
Cho, K.A.1
Sung, J.R.2
Yoon, S.O.3
Ji, H.P.4
Jung, W.L.5
Kim, H.-P.6
Kyung, T.K.7
Ik, S.J.8
Sang, C.P.9
-
45
-
-
0036323674
-
Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
-
Volonte D, Zhang K, Lisanti MP et al. Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts. Mol Biol Cell 2002; 13:2502-2517.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2502-2517
-
-
Volonte, D.1
Zhang, K.2
Lisanti, M.P.3
-
46
-
-
0035896560
-
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton and focal adhesions as mechanical sensors of osmotic stress
-
Volonte D, Galbiati F, Pestell RG et al. Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton and focal adhesions as mechanical sensors of osmotic stress. The Journal of Biological Chemistry 2001; 276:8094-8103.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 8094-8103
-
-
Volonte, D.1
Galbiati, F.2
Pestell, R.G.3
-
47
-
-
2442454750
-
3 Induces Cyclooxygenase-2 Expression and Prostacyclin Release in Human Endothelial Cells Via a p38 MAPK/CRE-Dependent Pathway: Effects on COX-2/PGI-Synthase Coupling
-
DOI 10.1161/01.ATV.zhq0504.1403
-
Norata GD, Callegari E, Inoue H et al. HDL3 induces cyclooxygenase-2 expression and prostacyclin release in human endothelial cells via a p38 MAPK/CRE-dependent pathway: effects on COX-2/PGI-synthase coupling. Arterioscler Thromb Vasc Biol 2004; 24:871-877. (Pubitemid 38620865)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.5
, pp. 871-877
-
-
Norata, G.D.1
Callegari, E.2
Inoue, H.3
Catapano, A.L.4
-
48
-
-
2342423629
-
Cdc42-dependent Mediation of UV-induced p38 Activation by G Protein βγ Subunits
-
DOI 10.1074/jbc.M312442200
-
Seo M, Cho CH, Lee YI et al. Cdc42-dependent mediation of UV-induced p38 activation by G protein betagamma subunits. The Journal of Biological Chemistry 2004; 279:17366-17375. (Pubitemid 38560497)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.17
, pp. 17366-17375
-
-
Seo, M.1
Cho, C.-H.2
Lee, Y.-I.3
Shin, E.-Y.4
Park, D.5
Bae, C.-D.6
Lee, J.W.7
Lee, E.-S.8
Juhnn, Y.-S.9
-
49
-
-
43549100630
-
Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H(2)O 2)-induced premature senescence and interplay with p38alpha(MAPK)
-
Chretien A, Piront N, Delaive E et al. Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H(2)O(2)-induced premature senescence and interplay with p38alpha(MAPK). FEBS Letters 2008; 582:1685-1692.
-
(2008)
FEBS Letters
, vol.582
, pp. 1685-1692
-
-
Chretien, A.1
Piront, N.2
Delaive, E.3
-
50
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
DOI 10.1016/S0092-8674(00)81902-9
-
Serrano M, Lin AW, McCurrach ME et al. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997; 88:593-602. (Pubitemid 27152402)
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
52
-
-
0034704916
-
Defects in TGFβ signaling overcome senescence of mouse keratinocytes expressing v-ras(Ha)
-
Tremain R, Marko M, Kinnimulki V et al. Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras. Oncogene 2000; 19:1698-1709. (Pubitemid 30200972)
-
(2000)
Oncogene
, vol.19
, Issue.13
, pp. 1698-1709
-
-
Tremain, R.1
Marko, M.2
Kinnimulki, V.3
Ueno, H.4
Bottinger, E.5
Glick, A.6
-
55
-
-
0027138356
-
The role of p21ras in receptor tyrosine kinase signaling
-
Medema RH, Bos JL. The role of p21ras in receptor tyrosine kinase signaling. Crit Rev Oncog 1993; 4:615-661. (Pubitemid 2002497)
-
(1993)
Critical Reviews in Oncogenesis
, vol.4
, Issue.6
, pp. 615-661
-
-
Medema, R.H.1
Bos, J.L.2
-
57
-
-
0035156849
-
Escape from premature senescence is not sufficient for oncogenic transformation by ras
-
DOI 10.1038/35055110
-
Peeper DS, Dannenberg JH, Douma S et al. Escape from premature senescence is not sufficient for oncogenic transformation by Ras. Nat Cell Biol 2001; 3:198-203. (Pubitemid 32118374)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.2
, pp. 198-203
-
-
Peeper, D.S.1
Dannenberg, J.-H.2
Douma, S.3
Te Riele, H.4
Bernards, R.5
-
58
-
-
0037087737
-
ARF-p53 signaling
-
DOI 10.1101/gad.929302
-
Shvarts A, Brummelkamp TR, Scheeren F et al. A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. Genes Dev 2002; 16:681-686. (Pubitemid 34274037)
-
(2002)
Genes and Development
, vol.16
, Issue.6
, pp. 681-686
-
-
Shvarts, A.1
Brummelkamp, T.R.2
Scheeren, F.3
Koh, E.4
Daley, G.Q.5
Spits, H.6
Bernards, R.7
-
59
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
DOI 10.1038/5063
-
Morales CP, Holt SE, Ouellette M et al. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase. Nat Genet 1999; 21:115-118. (Pubitemid 29036296)
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
60
-
-
0036118368
-
Enumeration of the simian virus 40 early region elements necessary for human cell transformation
-
DOI 10.1128/MCB.22.7.2111-2123.2002
-
Hahn WC, Dessain SK, Brooks MW et al. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol Cell Biol 2002; 22:2111-2123. (Pubitemid 34224619)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2111-2123
-
-
Hahn, W.C.1
Dessain, S.K.2
Brooks, M.W.3
King, J.E.4
Elenbaas, B.5
Sabatini, D.M.6
DeCaprio, J.A.7
Weinberg, R.A.8
-
61
-
-
0022486653
-
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes
-
Franza BR Jr, Maruyama K, Garrels JI et al. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell 1986; 44:409-418. (Pubitemid 16043332)
-
(1986)
Cell
, vol.44
, Issue.3
, pp. 409-418
-
-
Franza Jr., B.R.1
Maruyama, K.2
Garrels, J.I.3
Ruley, H.E.4
-
62
-
-
0040433650
-
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene
-
Hirakawa T, Ruley HE. Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc Natl Acad Sci USA 1988; 85:1519-1523. (Pubitemid 18070798)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.5
, pp. 1519-1523
-
-
Hirakawa, T.1
Ruley, H.R.2
-
63
-
-
0026074818
-
Cooperation between oncogenes
-
Hunter T. Cooperation between oncogenes. Cell 1991; 64:249-270. (Pubitemid 121001253)
-
(1991)
Cell
, vol.64
, Issue.2
, pp. 249-270
-
-
Hunter, T.1
-
64
-
-
0025142733
-
Transforming collaborations between ras and nuclear oncogenes
-
Ruley HE. Transforming collaborations between ras and nuclear oncogenes. Cancer Cells 1990; 2:258-268. (Pubitemid 20290108)
-
(1990)
Cancer Cells
, vol.2
, Issue.8-9
, pp. 258-268
-
-
Ruley, H.E.1
-
65
-
-
0024399684
-
Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis
-
Weinberg RA. Oncogenes, antioncogenes and the molecular bases of multistep carcinogenesis. Cancer Res 1989; 49:3713-3721. (Pubitemid 19197385)
-
(1989)
Cancer Research
, vol.49
, Issue.14
, pp. 3713-3721
-
-
Weinberg, R.A.1
-
66
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee AC, Fenster BE, Ito H et al. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. The Journal of Biological Chemistry 1999; 274:7936-7940.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
-
68
-
-
0033963144
-
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast
-
DOI 10.1016/S0891-5849(99)00249-X, PII S089158499900249X
-
Dumont P, Burton M, Chen QM et al. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast. Free Radical Biology & Medicine 2000; 28:361-373. (Pubitemid 30110651)
-
(2000)
Free Radical Biology and Medicine
, vol.28
, Issue.3
, pp. 361-373
-
-
Dumont, P.1
Burton, M.2
Chen, Q.M.3
Gonos, E.S.4
Frippiat, C.5
Mazarati, J.-B.6
Eliaers, F.7
Remacle, J.8
Toussaint, O.9
-
69
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
Lin AW, Barradas M, Stone JC et al. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 1998; 12:3008-3019. (Pubitemid 28469303)
-
(1998)
Genes and Development
, vol.12
, Issue.19
, pp. 3008-3019
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
Van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
70
-
-
0032192153
-
Senescence of human fibroblasts induced by oncogenic Raf
-
Zhu J, Woods D, McMahon M et al. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev 1998; 12:2997-3007. (Pubitemid 28469302)
-
(1998)
Genes and Development
, vol.12
, Issue.19
, pp. 2997-3007
-
-
Zhu, J.1
Woods, D.2
McMahon, M.3
Bishop, J.M.4
-
71
-
-
0038246249
-
Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a
-
DOI 10.1128/MCB.23.11.3859-3871.2003
-
Bulavin DV, Kovalsky O, Hollander MC et al. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen- activated protein kinase activation by disruption of Gadd45a. Mol Cell Biol 2003; 23:3859-3871. (Pubitemid 36597465)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.11
, pp. 3859-3871
-
-
Bulavin, D.V.1
Kovalsky, O.2
Hollander, M.C.3
Fornace Jr., A.J.4
-
72
-
-
0344604528
-
Genomic instability in Gadd45a-deficient mice
-
DOI 10.1038/13802
-
Hollander MC, Sheikh MS, Bulavin DV et al. Genomic instability in Gadd45a-deficient mice. Nat Genet 1999; 23:176-184. (Pubitemid 29455389)
-
(1999)
Nature Genetics
, vol.23
, Issue.2
, pp. 176-184
-
-
Hollander, M.C.1
Sheikh, M.S.2
Bulavin, D.V.3
Lundgren, K.4
Augeri-Henmueller, L.5
Shehee, R.6
Molinaro, T.A.7
Kim, K.E.8
Tolosa, E.9
Ashwell, J.D.10
Rosenberg, M.P.11
Zhan, Q.12
Fernandez-Salguero, P.M.13
Morgan, W.F.14
Deng, C.-X.15
Fornace Jr., A.J.16
-
73
-
-
0029040101
-
Developmental and tissue-specific regulation of mouse telomerase and telomere length
-
Prowse KR, Greider CW. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc Natl Acad Sci USA 1995; 92:4818-4822.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4818-4822
-
-
Prowse, K.R.1
Greider, C.W.2
-
74
-
-
0041660960
-
Mechanism of p38 MAP kinase activation in vivo
-
DOI 10.1101/gad.1107303
-
Brancho D, Tanaka N, Jaeschke A et al. Mechanism of p38 MAP kinase activation in vivo. Genes Dev 2003; 17:1969-1978. (Pubitemid 36999324)
-
(2003)
Genes and Development
, vol.17
, Issue.16
, pp. 1969-1978
-
-
Brancho, D.1
Tanaka, N.2
Jaeschke, A.3
Ventura, J.-J.4
Kelkar, N.5
Tanaka, Y.6
Kyuuma, M.7
Takeshita, T.8
Flavell, R.A.9
Davis, R.J.10
-
75
-
-
0037083375
-
MAPKK-independent activation of p38α mediated by TAB1-dependent autophosphorylation of p38α
-
DOI 10.1126/science.1067289
-
Ge B, Gram H, Di Padova F et al. MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. Science 2002; 295:1291-1294. (Pubitemid 34157620)
-
(2002)
Science
, vol.295
, Issue.5558
, pp. 1291-1294
-
-
Ge, B.1
Gram, H.2
Di Padova, F.3
Huang, B.4
New, L.5
Ulevitch, R.J.6
Luo, Y.7
Han, J.8
-
76
-
-
0042525992
-
Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: Evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia
-
DOI 10.1161/01.RES.0000083490.43943.85
-
Tanno M, Bassi R, Gorog DA et al. Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia. Circ Res 2003; 93:254-261. (Pubitemid 36993237)
-
(2003)
Circulation Research
, vol.93
, Issue.3
, pp. 254-261
-
-
Tanno, M.1
Bassi, R.2
Gorog, D.A.3
Saurin, A.T.4
Jiang, J.5
Heads, R.J.6
Martin, J.L.7
Davis, R.J.8
Flavell, R.A.9
Marber, M.S.10
-
77
-
-
0034472888
-
Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide
-
Chen QM, Tu VC, Catania J et al. Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide. J Cell Sci 2000; 113(Pt 22):4087-4097. (Pubitemid 32194533)
-
(2000)
Journal of Cell Science
, vol.113
, Issue.22
, pp. 4087-4097
-
-
Chen, Q.M.1
Tu, V.C.2
Catania, J.3
Burton, M.4
Toussaint, O.5
Dilley, T.6
|