Bcl-xL and E1B-19K Proteins Inhibit p53-induced Irreversible Growth Arrest and Senescence by Preventing Reactive Oxygen Species-dependent p38 Activation

Journal of Biological Chemistry

Volumn 279, Issue 17, 2004, Pages 17765-17771

  Jung, Mun Su ^a,b,c   Jin, Dong Hoon ^a,b,d   Chae, Hee Don ^a,b   Kang, Seokwon ^b   Kim, Sun Chang ^c   Bang, Yung Jue ^b   Choi, Tae Saeng ^a   Choi, Kyeong Sook ^e   Shin, Deug Y ^a,b  

^a Dankook University College of Medicine   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^d Sogang University   (South Korea)

^e Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; CELLS; FUNCTIONS; OXYGEN; PROTEINS;

CHEMICAL INHIBITORS; ONCOGENIC POTENTIAL; SENESCENCE; TRANSIENT GROWTH;

BIOCHEMISTRY;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTIOXIDANT; E1B PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL XL; PROTEIN E1B 19K; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BCL2L1 PROTEIN, HUMAN; BETA GALACTOSIDASE; BROXURIDINE; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; OXIDIZING AGENT; PROTEIN BCL 2; PROTEIN BCL X; PYRIDINE DERIVATIVE;

APOPTOSIS; ARTICLE; CARCINOGENIC ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVATION; GROWTH DISORDER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE; TUMOR SUPPRESSOR GENE; CELL AGING; CELL DIVISION; IMMUNOBLOTTING; METABOLISM; PHENOTYPE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; TIME; TUMOR CELL LINE;

ADENOVIRUS E1B PROTEINS; ANTIOXIDANTS; APOPTOSIS; BCL-X PROTEIN; BETA-GALACTOSIDASE; BROMODEOXYURIDINE; CELL AGING; CELL DIVISION; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; IMIDAZOLES; IMMUNOBLOTTING; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDANTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIDINES; REACTIVE OXYGEN SPECIES; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2342431845     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305015200     Document Type: Article

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