Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); Comparison of its substrate specificity with that of other SAP kinases

EMBO Journal

Volumn 16, Issue 12, 1997, Pages 3563-3571

  Goedert, Michel ^a   Cuenda, Ana ^b   Craxton, Molly ^a   Jakes, Ross ^a   Cohen, Philip ^a,b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cytokine; IL1; MAP kinase; MEK; Stress; TNF

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; HEAT SHOCK PROTEIN; INTERLEUKIN 1; MESSENGER RNA; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CELL STRAIN KB; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CLONING, MOLECULAR; COS CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; INTERLEUKIN-1; MAP KINASE KINASE 4; MAP KINASE KINASE 6; MITOGEN-ACTIVATED PROTEIN KINASE 12; MITOGEN-ACTIVATED PROTEIN KINASE 13; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PYRIDINES; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TUMOR NECROSIS FACTOR-ALPHA; XENOPUS;

ANIMALIA; CERVUS ELAPHUS;

EID: 0030927106     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.12.3563     Document Type: Article

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