Properties of purified recombinant human polyamine oxidase, PAOh1/SMO

Biochemical and Biophysical Research Communications

Volumn 304, Issue 4, 2003, Pages 605-611

  Wang, Yanlin ^a   Murray Stewart, Tracy ^a   Devereux, Wendy ^a   Hacker, Amy ^a   Frydman, Benjamin ^b   Woster, Patrick M ^c   Casero Jr , Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b SLIL Biomedical Corp   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

FAD dependent; H2O2; Polyamines; Spermidine spermine N1 acetyltransferase

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; N1 (2 METHYL 1 BUTYL) 4,8 DIAZAUNDECANE; N1 ACETYLSPERMINE; N1 ETHYL N11 (CYCLOHEPTYL)METHYL 4,8 DIAZAUNDECANE; N1 ETHYL N11 (CYCLOPROPYL)METHYL 4,8 DIAZAUNDECANE; N1,N11 DIETHYLNORSPERMINE; POLYAMINE DERIVATIVE; POLYAMINE OXIDASE; RECOMBINANT ENZYME; SL 11093; SL 11144; SL 11150; SL 11158; SPERMIDINE; SPERMINE; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG OXIDATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PURIFICATION; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0037449190     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00636-3     Document Type: Article

References (42)

1. Thomas T., Thomas T.J. Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell. Mol. Life Sci. 58:2001;244-258.
2. 11 -diethylnorspermine against human prostate carcinoma cells Prostate. 44:2000;313-321.
3. Marton L.J., Pegg A.E. Polyamines as targets for therapeutic intervention. Annu. Rev. Pharmacol. Toxicol. 35:1995;55-91.
4. Casero R.A., Woster P.M. Terminally alkylated polyamine analogues as chemotherapeutic agents. J. Med. Chem. 44:2001;1-26.
5. Davidson N.E., Hahm H.A., McCloskey D.E., Woster P.M., Casero R.A. Jr. Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment. Endocr. Relat. Cancer. 6:1999;69-73.
6. Ha H.C., Woster P.M., Yager J.D., Casero R.A. Jr. The role of polyamine catabolism in polyamine analogue-induced programmed cell death. Proc. Natl. Acad. Sci. USA. 94:1997;11557-11562.
7. Chen Y., Kramer D.L., Diegelman P., Vujcic S., Porter C.W. Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells. Cancer Res. 61:2001;6437-6444.
8. 1 -acetyltransferase-the turning point in polyamine metabolism FASEB J. 7:1993;653-661.
9. 1 -acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues Cancer Res. 49:1989;3829-3833.
10. 12 -bis(ethyl)spermine in human cell lines representing the major forms of lung cancer Cancer Res. 52:1992;5359-5363.
11. 11 -bis(ethyl)norspermine Clin. Cancer Res. 5:1999;1638-1641.
12. 1 -acetyltransferase gene expression Biochemistry. 35:1996;14436-14444.
13. 1 -acetyltransferase activity by novel spermine analogs Mol. Pharmacol. 52:1997;69-74.
14. 1 -acetyltransferase activity as a mechanism of cellular resistance to bis(ethyl)polyamine analogues J. Biol. Chem. 275:2000;28708-28714.
15. 1 -acetyltransferase on polyamine pool dynamics, cell growth, sensitivity to polyamine analogs J. Biol. Chem. 275:2000;38319-38328.
16. Holtta E. Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase. Biochemistry. 16:1977;91-100.
17. Holtta E. Polyamine oxidase (rat liver). Methods Enzymol. 94:1983;306-311.
18. Seiler N. Polyamine oxidase, properties and functions. Prog. Brain Res. 106:1995;333-344.
19. Vujcic S., Liang P., Diegelman P., Kramer D., Porter C.W. Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. Biochem J. 370:2003;19-28.
20. Wang Y., Devereux W., Woster P.M., Stewart T.M., Hacker A., Casero R.A. Jr. Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure. Cancer Res. 61:2001;5370-5373.
21. Murray-Stewart T., Wang Y., Devereux W., Casero R.A. Cloning and characterization of human polyamine oxidase splice variants. Proc. Am. Assoc. Cancer Res. 43:2002;1120-1121.
22. Vujcic S., Diegelman P., Bacchi C.J., Kramer D.L., Porter C.W. Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. Biochem. J. 367:2002;665-675.
23. Webb H.K., Wu Z., Sirisoma N., Ha H.C., Casero R.A. Jr., Woster P.M. 1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization. J. Med. Chem. 42:1999;1415-1421.
24. 12 -bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines J. Med. Chem. 41:1998;4723-4732.
25. Reddy V.K., Sarkar A., Valasinas A., Marton L.J., Basu H.S., Frydman B. cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines. J. Med. Chem. 44:2001;404-417.
26. 14 -bisethylhomospermine (be-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells J. Med. Chem. 44:2001;390-403.
27. Bey P., Bolkenius F.N., Seiler N., Casara P. N-2,3-butadienyl-1,4 derivatives: potent irreversible inactivators of mammalian polyamine oxidase. J. Med. Chem. 28:1985;1-2.
28. Fernandez C., Sharrard R.M., Talbot M., Reed B.D., Monks N. Evaluation of the significance of polyamines and their oxidases in the aetiology of human cervical carcinoma. Br. J. Cancer. 72:1995;1194-1199.
29. Rogers M.S., Yim S.F., Li K.C., Wang C.C., Arumanayagam M. Cervical intraepithelial neoplasia is associated with increased polyamine oxidase and diamine oxidase concentrations in cervical mucus. Gynecol. Oncol. 84:2002;383-387.
30. 1 -(N-octanesulfonyl)spermine and human colon cancer cells Int. J. Biochem. Cell. Biol. 32:2000;703-716.
31. 11 -[(cycloheptyl)methy]-4,8-diazaundecane (chenspm) by polyamine oxidase Clin. Cancer Res. 8:2002;1241-1247.
32. Binda C., Angelini R., Federico R., Ascenzi P., Mattevi A. Structural bases for inhibitor binding and catalysis in polyamine oxidase. Biochemistry. 40:2001;2766-2776.
33. Lamond S., Wallace H.M. Polyamine oxidase activity and growth in human cancer cells. Biochem. Soc. Trans. 22:1994;396S.
34. Wallace H.M., Duthie J., Evans D.M., Lamond S., Nicoll K.M., Heys S.D. Alterations in polyamine catabolic enzymes in human breast cancer tissue. Clin. Cancer Res. 6:2000;3657-3661.
35. Casero R.A., Wang Y., Stewart T.M., Devereux W., Hacker A., Smith R., Woster P.M. The role of polyamine catabolism in antitumor drug response. Biochem. Soc. Trans. 31:2003;361-365.
36. Murray-Stewart T., Wang Y., Devereux W., Casero R.A. Jr. Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics. Biochem. J. 368:2002;673-677.
37. 1 -acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues J. Biol. Chem. 277:2002;25323-25328.
38. Hartl F.U., Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science. 295:2002;1852-1858.
39. Federico R., Alisi C., Cona A., Angelini R. Purification of polyamine oxidase from maize seedlings by immunoadsorbent column. Adv. Exp. Med. Biol. 250:1988;617-623.
40. Federico R., Cona A., Angelini R., Schinina M.E., Giartosio A. Characterization of maize polyamine oxidase. Phytochemistry. 29:1990;2411-2414.
41. 1 -(N-octanesulfonyl)spermine toxicity Int. J. Biochem. Cell. Biol. 32:2000;1055-1068.
42. Devereux W., Wang Y., Murray-Stewart T., Hacker A., Casero R.A. Differential induction of polyamine oxidase by polyamine analogues in various human lung carcinoma lines. Proc. Am. Assoc. Cancer Res. 43:2002;963-964.