Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase

ACS Chemical Biology

Volumn 8, Issue 8, 2013, Pages 1677-1682

  Tortorici, Marcello ^a   Borrello, Maria Teresa ^b   Tardugno, Maria ^b,c   Chiarelli, Laurent R ^a   Pilotto, Simona ^a   Ciossani, Giuseppe ^a   Vellore, Nadeem A ^d   Bailey, Sarah G ^e   Cowan, Jonathan ^b   O'Connell, Maria ^b   Crabb, Simon J ^e   Packham, Graham ^e   Mai, Antonello ^c   Baron, Riccardo ^d   Ganesan, A ^b   Mattevi, Andrea ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF UTAH   (United States)

^e SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ENZYME INHIBITOR; HEXAPEPTIDE; LYSINE DEMETHYLASE 1 INHIBITOR; LYSINE DEMETHYLASE LSD1; METHYLTRANSFERASE; PEPTIDE DERIVATIVE; PEPTIDOMIMETIC AGENT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN HL 60; CHROMATIN MODIFICATION; CIRCULAR DICHROISM; COMBINATORIAL CHEMISTRY; COMPLEX FORMATION; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; MOLECULE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CELL PROLIFERATION; ENZYME INHIBITORS; HISTONE DEMETHYLASES; HUMANS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN BINDING; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84880777273     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb4001926     Document Type: Article

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