Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1 (DNA methyltransferase 1)-independent manner

Biochemical Journal

Volumn 449, Issue 2, 2013, Pages 459-468

  Jin, Lihua ^a   Hanigan, Christin L ^a   Wu, Yu ^a   Wang, Wei ^a,b   Park, Ben Ho ^a   Woster, Patrick M ^c   Casero, Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Chromatin; Epigenetics; FAD dependent oxidase; Histone modification; Transcriptional repression

Indexed keywords

DNA METHYLTRANSFERASE 1; LYSINE DERIVATIVE; LYSINE SPECIFIC DEMETHYLASE 1; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL STRAIN HCT116; COLON CANCER; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION;

EID: 84871419643     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121360     Document Type: Article

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