Activation of the phase ii enzymes for neuroprotection by ginger active constituent 6-dehydrogingerdione in PC12 cells

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 24, 2014, Pages 5507-5518

  Yao, Juan ^a   Ge, Chunpo ^a   Duan, Dongzhu ^a   Zhang, Baoxin ^a   Cui, Xuemei ^a   Peng, Shoujiao ^a   Liu, Yaping ^a   Fang, Jianguo ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

6 dehydrogingerdione; antioxidant; neuroprotection; Nrf2; oxidative stress

Indexed keywords

ANTIOXIDANTS; CELL CULTURE; CHEMICAL ACTIVATION; CHEMICAL COMPOUNDS; FOOD ADDITIVES; FREE RADICALS; GENES; MOLECULES; NEURONS; OXIDATIVE STRESS; CYTOLOGY; MOBILE SECURITY; NEURODEGENERATIVE DISEASES;

6-DEHYDROGINGERDIONE; ANTIOXIDANT SYSTEMS; NEUROPROTECTION; NEUROPROTECTIVE AGENTS; NRF2; PHARMACOLOGICAL ACTIVITY; PHEOCHROMOCYTOMA CELL LINE; THIOREDOXIN REDUCTASE; MECHANISTIC STUDIES;

CELLS;

RATTUS; ZINGIBER OFFICINALE;

6-DEHYDROGINGERDIONE; ANTIOXIDANT; CASP3 PROTEIN, RAT; CASPASE 3; FATTY ALCOHOL; GLUTATHIONE; GUAIACOL; HEME OXYGENASE; KEAP1 PROTEIN, RAT; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, RAT; NQO1 PROTEIN, RAT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SCAVENGER; SIGNAL PEPTIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR NRF2;

ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CELL PROTECTION; CHEMISTRY; DRUG EFFECTS; ERYTHROCYTE; GENETICS; GINGER; METABOLISM; OXIDATIVE STRESS; PC12 CELL LINE; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CYTOPROTECTION; ERYTHROCYTES; FATTY ALCOHOLS; FREE RADICAL SCAVENGERS; GINGER; GLUTATHIONE; GUAIACOL; HEME OXYGENASE (DECYCLIZING); INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NAD(P)H DEHYDROGENASE (QUINONE); NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THIOREDOXIN-DISULFIDE REDUCTASE; UP-REGULATION;

EID: 84902668740     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf405553v     Document Type: Article

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