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Volumn 8, Issue 2, 2005, Pages 125-132

Ginger - An herbal medicinal product with broad anti-inflammatory actions

Author keywords

Chemokines; Cyclooxygenase; Cytokines; Ginger; Inflammation

Indexed keywords

3 METHOXY 4 HYDROXYPHENOL DERIVATIVE; ACETOXYCHAVICOL ACETATE; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; CHEMOKINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GINGER EXTRACT; GINGEROL; HERBACEOUS AGENT; HYDROXYL GROUP; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; KETONE DERIVATIVE; LEUKOTRIENE; MONOCYTE CHEMOTACTIC PROTEIN 1; NONSTEROID ANTIINFLAMMATORY AGENT; PARADOL; PHENOL DERIVATIVE; PROSTAGLANDIN; SHOGAOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; ZINGERONE;

EID: 22444431608     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2005.8.125     Document Type: Review
Times cited : (584)

References (76)
  • 5
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 1971;231:232-235.
    • (1971) Nature New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 6
    • 0019949095 scopus 로고
    • Inhibitors of prostaglandin biosynthesis from ginger
    • Kiuchi F, Shibuya M, Sankawa U: Inhibitors of prostaglandin biosynthesis from ginger. Chem Pharm Bull (Tokyo) 1982;30: 754-757.
    • (1982) Chem Pharm Bull (Tokyo) , vol.30 , pp. 754-757
    • Kiuchi, F.1    Shibuya, M.2    Sankawa, U.3
  • 7
    • 0022498788 scopus 로고
    • Inhibition of human neurotrophil 5-lipoxygenase activity by gingerdione, shagaol, capsaicin and related pungent compounds
    • Flynn DL, Rafferty MF: Inhibition of human neurotrophil 5-lipoxygenase activity by gingerdione, shagaol, capsaicin and related pungent compounds. Prostaglandins Leukot Med 1986;24: 195-198.
    • (1986) Prostaglandins Leukot Med , vol.24 , pp. 195-198
    • Flynn, D.L.1    Rafferty, M.F.2
  • 8
    • 0034949189 scopus 로고    scopus 로고
    • Anti-inflammatory drugs: New multitarget compounds to face an old problem. The dual inhibition concept
    • Celotti F, Laufer S: Anti-inflammatory drugs: New multitarget compounds to face an old problem. The dual inhibition concept. Pharmacol Res 2001;43:429-436.
    • (2001) Pharmacol Res , vol.43 , pp. 429-436
    • Celotti, F.1    Laufer, S.2
  • 9
    • 0035584272 scopus 로고    scopus 로고
    • Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue to anti-inflammatory therapy?
    • Fiorucci S, Meli R, Bucci M, Cirino G: Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue to anti-inflammatory therapy? Biochem Pharmacol 2001;62:1433-1438.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1433-1438
    • Fiorucci, S.1    Meli, R.2    Bucci, M.3    Cirino, G.4
  • 10
    • 0038147318 scopus 로고    scopus 로고
    • Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
    • Martel-Pelletier J, Lajeunesse D, Reboul P, Pelletier J-P: Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Ann Rheum Dis 2003;62:501-509.
    • (2003) Ann Rheum Dis , vol.62 , pp. 501-509
    • Martel-Pelletier, J.1    Lajeunesse, D.2    Reboul, P.3    Pelletier, J.-P.4
  • 11
    • 0037955831 scopus 로고    scopus 로고
    • Anti-cytokine therapeutics and infections
    • Dinarello CA: Anti-cytokine therapeutics and infections. Vaccine 2003;21(Suppl):S2/24-S22/34.
    • (2003) Vaccine , vol.21 , Issue.SUPPL.
    • Dinarello, C.A.1
  • 12
    • 84860962420 scopus 로고    scopus 로고
    • http://www.herbmed.org/herbs/herb138.htm (accessed 18 April 2005).
  • 13
    • 0035151805 scopus 로고    scopus 로고
    • Effects of a ginger extract on knee pain in patients with osteoarthritis
    • Altman RD, Marcussen KC: Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44: 2461-2462.
    • (2001) Arthritis Rheum , vol.44 , pp. 2461-2462
    • Altman, R.D.1    Marcussen, K.C.2
  • 15
    • 0242522200 scopus 로고    scopus 로고
    • The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis
    • Wigler I, Grotto I, Caspi D, Yaron M: The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage 2003;11:783-789.
    • (2003) Osteoarthritis Cartilage , vol.11 , pp. 783-789
    • Wigler, I.1    Grotto, I.2    Caspi, D.3    Yaron, M.4
  • 17
    • 2142753013 scopus 로고    scopus 로고
    • Diarylheptanoids from the rhizomes of Zingiber officinale
    • Ma J, Jin XJ, Yang L, Liu Z-L: Diarylheptanoids from the rhizomes of Zingiber officinale. Phytochemistry 2004;65:1137-1143.
    • (2004) Phytochemistry , vol.65 , pp. 1137-1143
    • Ma, J.1    Jin, X.J.2    Yang, L.3    Liu, Z.-L.4
  • 19
    • 0033758686 scopus 로고    scopus 로고
    • New gingerdione from the rhizomes of Zingiber officinale
    • Charles R, Garg SN, Kumar S: New gingerdione from the rhizomes of Zingiber officinale. Fitoterapia 2000;71:716-718.
    • (2000) Fitoterapia , vol.71 , pp. 716-718
    • Charles, R.1    Garg, S.N.2    Kumar, S.3
  • 20
    • 0035574475 scopus 로고    scopus 로고
    • Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells
    • Tjendraputra E, Tran VH, Liu-Brennan D, Roufogalis BD, Duke CC: Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells. Bioorg Chem 2001;29: 156-163.
    • (2001) Bioorg Chem , vol.29 , pp. 156-163
    • Tjendraputra, E.1    Tran, V.H.2    Liu-Brennan, D.3    Roufogalis, B.D.4    Duke, C.C.5
  • 21
    • 0026505808 scopus 로고
    • Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diaryl heptanoids
    • Kiuchi F, Iwakami S, Shibuya M, Hanaoka F, Sankawa U: Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diaryl heptanoids. Chem Pharm Bull (Tokyo) 1992;40:387-391.
    • (1992) Chem Pharm Bull (Tokyo) , vol.40 , pp. 387-391
    • Kiuchi, F.1    Iwakami, S.2    Shibuya, M.3    Hanaoka, F.4    Sankawa, U.5
  • 23
    • 0023000630 scopus 로고
    • Isolation and effects of some ginger compounds on platelet aggregation and eicosanoid biosynthesis
    • Srivastava K: Isolation and effects of some ginger compounds on platelet aggregation and eicosanoid biosynthesis. Prostaglandins Leukot Med 1986;25:187-198.
    • (1986) Prostaglandins Leukot Med , vol.25 , pp. 187-198
    • Srivastava, K.1
  • 25
    • 2142695733 scopus 로고    scopus 로고
    • Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic
    • Warner TD, Mitchell JA: Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic. FASEB J 2004;18:790-804.
    • (2004) FASEB J , vol.18 , pp. 790-804
    • Warner, T.D.1    Mitchell, J.A.2
  • 27
    • 0038560046 scopus 로고
    • Stomachic principles in ginger. An anti-ulcer principle 6-gingesulfonic acid, and three monoacyldigalactosylglycerols gingerglycolipids A, B, and C, from Zingiber rhizome originating in Taiwan
    • Yoshikawa M, Yamagashi S, Kumini K, Matsuda H, Okuno Y, Yamashara J, Murakami A: Stomachic principles in ginger. An anti-ulcer principle 6-gingesulfonic acid, and three monoacyldigalactosylglycerols gingerglycolipids A, B, and C, from Zingiber rhizome originating in Taiwan. Chem Pharm Bull (Tokyo) 1994;42:226-230.
    • (1994) Chem Pharm Bull (Tokyo) , vol.42 , pp. 226-230
    • Yoshikawa, M.1    Yamagashi, S.2    Kumini, K.3    Matsuda, H.4    Okuno, Y.5    Yamashara, J.6    Murakami, A.7
  • 29
    • 0027294984 scopus 로고
    • Enhanced gastric mucosal leukotriene B4synthesis in patients taking non-steroidal antiinftammatory drugs
    • Hudson N, Balsitis M, Everitt S, Hawkey CJ: Enhanced gastric mucosal leukotriene B4synthesis in patients taking non-steroidal antiinftammatory drugs. Gut 1993;34:742-747.
    • (1993) Gut , vol.34 , pp. 742-747
    • Hudson, N.1    Balsitis, M.2    Everitt, S.3    Hawkey, C.J.4
  • 30
    • 0026742483 scopus 로고
    • Indomethacin-induced leukocyte adhesion in mesenteric venules: Role of lipoxygenase products
    • Asako H, Kubes P, Wallace J, Wolf RE, Granger DN: Indomethacin-induced leukocyte adhesion in mesenteric venules: Role of lipoxygenase products. Am J Physiol 1992;262:G903-G908.
    • (1992) Am J Physiol , vol.262
    • Asako, H.1    Kubes, P.2    Wallace, J.3    Wolf, R.E.4    Granger, D.N.5
  • 31
    • 0029866858 scopus 로고    scopus 로고
    • The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation
    • Nickerson-Nutter CL, Medvedeff ED: The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation. Arthritis Rheum 1996;39:515-521.
    • (1996) Arthritis Rheum , vol.39 , pp. 515-521
    • Nickerson-Nutter, C.L.1    Medvedeff, E.D.2
  • 32
    • 0041328097 scopus 로고    scopus 로고
    • Role of eicosanoids in structural degradation in osteoarthritis
    • Laufer S: Role of eicosanoids in structural degradation in osteoarthritis. Curr Opin Rheumatol 2003;15:623-627.
    • (2003) Curr Opin Rheumatol , vol.15 , pp. 623-627
    • Laufer, S.1
  • 33
    • 0024670873 scopus 로고
    • Ginger (Zingiber officinale) and rheumatic disorders
    • Srivastava KC, Mustafa T: Ginger (Zingiber officinale) and rheumatic disorders. Med Hypotheses 1989;29:25-28.
    • (1989) Med Hypotheses , vol.29 , pp. 25-28
    • Srivastava, K.C.1    Mustafa, T.2
  • 34
    • 0027051053 scopus 로고
    • Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders
    • Srivastava K, Mustafa T: Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypotheses 1992;39: 342-348.
    • (1992) Med Hypotheses , vol.39 , pp. 342-348
    • Srivastava, K.1    Mustafa, T.2
  • 35
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EHS, Panayi GS: Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001;344:907-916.
    • (2001) N Engl J Med , vol.344 , pp. 907-916
    • Choy, E.H.S.1    Panayi, G.S.2
  • 36
    • 0036217821 scopus 로고    scopus 로고
    • Natural products as targeted modulators of the nuclear factor-κB pathway
    • Bremner P, Heinrich M: Natural products as targeted modulators of the nuclear factor-κB pathway. J Pharm Pharmacol 2001;54: 453-472.
    • (2001) J Pharm Pharmacol , vol.54 , pp. 453-472
    • Bremner, P.1    Heinrich, M.2
  • 37
    • 1642553221 scopus 로고    scopus 로고
    • Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
    • Lee H, Kim YO, Kim H, Kim SY, Noh HS, Kang SS, Cho GJ, Choi WS, Suk K: Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J 2003;17:1943-1944.
    • (2003) FASEB J , vol.17 , pp. 1943-1944
    • Lee, H.1    Kim, Y.O.2    Kim, H.3    Kim, S.Y.4    Noh, H.S.5    Kang, S.S.6    Cho, G.J.7    Choi, W.S.8    Suk, K.9
  • 38
    • 0034876980 scopus 로고    scopus 로고
    • Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells
    • Chang Y-L, Shen J-J, Wung B-S, Cheng J-J, Wang DL: Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Mol Pharmacol 2001;60:507-513.
    • (2001) Mol Pharmacol , vol.60 , pp. 507-513
    • Chang, Y.-L.1    Shen, J.-J.2    Wung, B.-S.3    Cheng, J.-J.4    Wang, D.L.5
  • 41
    • 0036258778 scopus 로고    scopus 로고
    • Zerumbone, a Southeast Asian ginger sequiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: The α,β-unsaturated carbonyl group is a prerequisite
    • Murakami A, Takahashi D, Kinoshita T, Koshima K, Kim HW, Yoshihiro A, Nakamura Y, Jiwajinda S, Ohigashi H: Zerumbone, a Southeast Asian ginger sequiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: The α,β-unsaturated carbonyl group is a prerequisite. Carcinogenesis 2002;23: 795-802.
    • (2002) Carcinogenesis , vol.23 , pp. 795-802
    • Murakami, A.1    Takahashi, D.2    Kinoshita, T.3    Koshima, K.4    Kim, H.W.5    Yoshihiro, A.6    Nakamura, Y.7    Jiwajinda, S.8    Ohigashi, H.9
  • 44
    • 33044483227 scopus 로고    scopus 로고
    • TNF-alpha expression of synoviocyte cultures is inhibited by hydroxy-alkoxy-phenyl compounds (HAPC) from ginger
    • Frondoza CG, Frazier C, Polotsky A, Lahiji K, Hungerford DS: TNF-alpha expression of synoviocyte cultures is inhibited by hydroxy-alkoxy-phenyl compounds (HAPC) from ginger. Trans Orthop Res Soc 2000;46:1038.
    • (2000) Trans Orthop Res Soc , vol.46 , pp. 1038
    • Frondoza, C.G.1    Frazier, C.2    Polotsky, A.3    Lahiji, K.4    Hungerford, D.S.5
  • 46
    • 4143153032 scopus 로고    scopus 로고
    • An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures
    • Frondoza CG, Sohrabi A, Polotsky A, Phan PV, Hungerford DS. Lindmark L: An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures. In Vitro 2004;30:95-101.
    • (2004) In Vitro , vol.30 , pp. 95-101
    • Frondoza, C.G.1    Sohrabi, A.2    Polotsky, A.3    Phan, P.V.4    Hungerford, D.S.5    Lindmark, L.6
  • 50
    • 0029785026 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in human and animal model of rheumatoid arthritis
    • Kang RY, Freire-Moar J, Sigal E, Chu CQ: Expression of cyclooxygenase-2 in human and animal model of rheumatoid arthritis. Br J Rheumatol 1996;35:711-718.
    • (1996) Br J Rheumatol , vol.35 , pp. 711-718
    • Kang, R.Y.1    Freire-Moar, J.2    Sigal, E.3    Chu, C.Q.4
  • 51
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-κB activation
    • Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Hahn KB: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: Down-regulation of COX-2 and iNOS through suppression of NF-κB activation. Mutat Res 2001;480-481:243-268.
    • (2001) Mutat Res , vol.480-481 , pp. 243-268
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3    Han, S.S.4    Keum, Y.S.5    Park, K.K.6    Hahn, K.B.7
  • 52
    • 0032933934 scopus 로고    scopus 로고
    • Specific COX-2 inhibitors in arthritis, oncology, and beyond: Where is the science headed?
    • Lipsky PE: Specific COX-2 inhibitors in arthritis, oncology, and beyond: Where is the science headed? J Rheumatol 1999;26: 25-30.
    • (1999) J Rheumatol , vol.26 , pp. 25-30
    • Lipsky, P.E.1
  • 53
    • 0028167846 scopus 로고
    • Inhibition of NF-κB by sodium salicylate and aspirin
    • Kopp E, Ghosh S: Inhibition of NF-κB by sodium salicylate and aspirin. Science 1994;265:956-959.
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 54
    • 0032949624 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes
    • Housby JN, Cahill CM, Chu B, Prevelige R, Bickford K, Sevenson MA, Calderwood SK: Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes. Cytokine 1998;11:347-358.
    • (1998) Cytokine , vol.11 , pp. 347-358
    • Housby, J.N.1    Cahill, C.M.2    Chu, B.3    Prevelige, R.4    Bickford, K.5    Ma, S.6    Calderwood, S.K.7
  • 56
    • 0032942060 scopus 로고    scopus 로고
    • Microglia as mediators of inflammatory and degenerative diseases
    • Gonzalez-Scarano F, Baltuch G: Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 1999; 22:219-240.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 219-240
    • Gonzalez-Scarano, F.1    Baltuch, G.2
  • 57
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW: Microglia: A sensor for pathological events in the CNS. Trends Neurosci 1996;19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 58
    • 0032937860 scopus 로고    scopus 로고
    • The role of microglia and macrophages in the pathophysiology of the CNS
    • Stoll G, Jander S: The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 1999;58:233-247.
    • (1999) Prog Neurobiol , vol.58 , pp. 233-247
    • Stoll, G.1    Jander, S.2
  • 60
    • 0036935553 scopus 로고    scopus 로고
    • An inflammatory review of Parkinson's disease
    • Orr CF, Rowe DB, Halliday GM: An inflammatory review of Parkinson's disease. Prog Neurobiol 2002;68:325-340.
    • (2002) Prog Neurobiol , vol.68 , pp. 325-340
    • Orr, C.F.1    Rowe, D.B.2    Halliday, G.M.3
  • 61
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophage/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste EN: Role of macrophage/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J Mol Med 1997;75:165-173.
    • (1997) J Mol Med , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 63
    • 0031960552 scopus 로고    scopus 로고
    • Age-related activation of microglia and astrocytes: In vitro studies show persistent phenotypes of aging, increased proliferation, and resistance to down-regulation
    • Rozovsky I, Finch CE, Morgan TE: Age-related activation of microglia and astrocytes: In vitro studies show persistent phenotypes of aging, increased proliferation, and resistance to down-regulation. Neurobiol Aging 1998;19:97-103.
    • (1998) Neurobiol Aging , vol.19 , pp. 97-103
    • Rozovsky, I.1    Finch, C.E.2    Morgan, T.E.3
  • 65
    • 0030897133 scopus 로고    scopus 로고
    • Risk of Alzheimer's disease and duration of NSAID use
    • Stewart WT, Kawas C, Corrada M, Metter EJ: Risk of Alzheimer's disease and duration of NSAID use. Neurology 1997;48:626-632.
    • (1997) Neurology , vol.48 , pp. 626-632
    • Stewart, W.T.1    Kawas, C.2    Corrada, M.3    Metter, E.J.4
  • 66
    • 13244273760 scopus 로고    scopus 로고
    • Ginger extract inhibits β-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes
    • Grzanna R, Phan PV, Polotsky A, Lindmark L, Frondoza CG: Ginger extract inhibits β-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes. J Altern Complement Med 2004;10:1009-1013.
    • (2004) J Altern Complement Med , vol.10 , pp. 1009-1013
    • Grzanna, R.1    Phan, P.V.2    Polotsky, A.3    Lindmark, L.4    Frondoza, C.G.5
  • 67
    • 0037162751 scopus 로고    scopus 로고
    • Protecting the brain while killing pain?
    • Helmuth L: Protecting the brain while killing pain? Science 2002;297:1262-1263.
    • (2002) Science , vol.297 , pp. 1262-1263
    • Helmuth, L.1
  • 68
    • 0030747128 scopus 로고    scopus 로고
    • NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle PA, Baichwal VR: NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv Immunol 1997;65:111-137.
    • (1997) Adv Immunol , vol.65 , pp. 111-137
    • Baeuerle, P.A.1    Baichwal, V.R.2
  • 69
    • 0031755148 scopus 로고    scopus 로고
    • Nuclear factor κB: A pivotal role in the systemic inflammatory response syndrome and new target for therapy
    • Christman JW, Lancaster LH, Blackwell TS: Nuclear factor κB: A pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Med 1998;24:1131-1138.
    • (1998) Intensive Care Med , vol.24 , pp. 1131-1138
    • Christman, J.W.1    Lancaster, L.H.2    Blackwell, T.S.3
  • 70
    • 0034746919 scopus 로고    scopus 로고
    • NF-κB: A key role in inflammatory diseases
    • Tak PP, Firestein GS: NF-κB: A key role in inflammatory diseases. J Clin Invest 2001;107:7-11.
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 72
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
    • Yamamoto Y, Gaynor RB: Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer. J Clin invest 2001;107:135-142.
    • (2001) J Clin Invest , vol.107 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 73
    • 3142781393 scopus 로고    scopus 로고
    • Anti-inflammatory agents for the treatment of musculoskeletal pain and arthritis
    • Fakata KL: Anti-inflammatory agents for the treatment of musculoskeletal pain and arthritis. Curr Pain Headache Rep 2004;8: 173-177.
    • (2004) Curr Pain Headache Rep , vol.8 , pp. 173-177
    • Fakata, K.L.1
  • 76
    • 0025134292 scopus 로고
    • Capsaicin inhibits responses of fine afferents from the knee joint of the cat to mechanical and chemical stimuli
    • He X, Schepelmann K, Schaible HG, Schmidt RF: Capsaicin inhibits responses of fine afferents from the knee joint of the cat to mechanical and chemical stimuli. Brain Res 1990;530: 147-150.
    • (1990) Brain Res , vol.530 , pp. 147-150
    • He, X.1    Schepelmann, K.2    Schaible, H.G.3    Schmidt, R.F.4


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