Enhancements of skin cell proliferations and migrations via 6-dehydrogingerdione

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 6, 2013, Pages 1349-1356

  Chen, Chung Yi ^a   Chiu, Chien Chih ^b   Wu, Chi Peng ^b   Chou, Yi Ting ^b   Wang, Hui Min ^b  

^a FOOYIN UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

6 dehydrogingerdione; collagen; growth factor; migration; skin cells

Indexed keywords

6-DEHYDROGINGERDIONE; BIOFUNCTIONAL; CELLULAR PROLIFERATIONS; CHEMICAL DAMAGES; COLLAGEN YIELD; ENZYMATIC ACTIVITIES; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED KINASE; GROWTH FACTOR; HEALING AGENTS; HUMAN SKIN; MIGRATION; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 12 MYRISTATE 13 ACETATES; PLATELET-DERIVED GROWTH FACTORS; PROTEIN EXPRESSIONS; PROTEIN LEVEL; REDUCED MATRIX; TISSUE INHIBITOR; TRANSFORMING GROWTH FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR; WOUND HEALING; WOUND REPAIR; ZINGIBER OFFICINALE;

CELL CULTURE; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLASTS; PHOSPHORYLATION;

COLLAGEN;

6 DEHYDROGINGERDIONE; 6-DEHYDROGINGERDIONE; DRUG DERIVATIVE; FATTY ALCOHOL; GUAIACOL; PLANT EXTRACT; PLATELET DERIVED GROWTH FACTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL MOTION; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; FIBROBLAST; GINGER; HUMAN; METABOLISM; SKIN;

CELL MOVEMENT; CELL PROLIFERATION; FATTY ALCOHOLS; FIBROBLASTS; GINGER; GUAIACOL; HUMANS; PLANT EXTRACTS; PLATELET-DERIVED GROWTH FACTOR; SKIN; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTOR BETA;

ZINGIBER OFFICINALE;

EID: 84873643404     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf304340q     Document Type: Article

References (41)

1. Afzal, M.; Al-Hadidi, D.; Menon, M.; Pesek, J.; Dhami, M. S. Ginger: an ethnomedical, chemical and pharmacological review Drug Metab. Drug Interact. 2001, 18, 159-190
2. Chen, B. H.; Wu, P. Y.; Chen, K. M.; Fu, T. F.; Wang, H. M.; Chen, C. Y. Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger) J. Nat. Prod. 2009, 72, 950-953
3. Wang, H. M.; Chen, C. Y.; Chen, H. A.; Huang, W. C.; Lin, W. R.; Chen, T. C.; Lin, C. Y.; Chien, H. J.; Lu, P. L.; Lin, C. M.; Chen, Y. H. Zingiber officinale (ginger) compounds have tetracycline-resistance modifying effects against clinical extensively drug-resistant Acinetobacter baumannii Phytother. Res. 2010, 24, 1825-1830
4. Koo, K. L.; Ammit, A. J.; Tran, V. H.; Duke, C. C.; Roufogalis, B. D. Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation Thromb. Res. 2001, 103, 387-397
5. Sumitra, M.; Manikandan, P.; Gayathri, V. S.; Mahendran, P.; Suguna, L. Emblica officinalis exerts wound healing action through up-regulation of collagen and extracellular signal-regulated kinases (ERK1/2) Wound Repair Regen. 2009, 17, 99-107
6. Tjendraputra, E.; Tran, V. H.; Liu-Brennan, D.; Roufogalis, B. D.; Duke, C. C. Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells Bioorg. Chem. 2001, 29, 156-163
7. Chan, E. W. C.; Lim, Y. Y.; Wong, L. F.; Lianto, F. S.; Wong, S. K.; Lim, K. K.; Joe, C. E.; Lim, T. Y. Antioxidant and tyrosinase inhibition properties of leaves and rhizomes of ginger species Food Chem. 2008, 109, 477-483
8. Choi, W.; Miyamura, Y.; Wolber, R.; Smuda, C.; Reinhold, W.; Liu, H.; Kolbe, L.; Hearing, V. J. Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB J. Invest. Dermatol. 2010, 130, 1685-1696
9. Kang, S.; Duell, E. A.; Fisher, G. J.; Datta, S. C.; Wang, Z. Q.; Reddy, A. P.; Tavakkol, A.; Yi, J. Y.; Griffiths, C. E.; Elder, J. T. Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation J. Invest. Dermatol. 1995, 105, 549-556
10. Chen, C. Y.; Cheng, K. C.; Chang, A. Y.; Lin, Y. T.; Hseu, Y. C.; Wang, H. M. 10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer Int. J. Mol. Sci. 2012, 13, 1762-1777
11. Rolfe, K. J.; Richardson, J.; Vigor, C.; Irvine, L. M.; Grobbelaar, A. O.; Linge, C. A role for TGF-β1-induced cellular responses during wound healing of the non-scarring early human fetus? J. Invest. Dermatol. 2007, 127, 2656-2667
12. Amjad, S. B.; Carachi, R.; Edward, M. Keratinocyte regulation of TGF-β and connective tissue growth factor expression: a role in suppression of scar tissue formation Wound Repair Regen. 2007, 15, 748-755
13. Heil, M.; Clauss, M.; Suzuki, K.; Buschmann, I. R.; Willuweit, A.; Fischer, S.; Schaper, W. Vascular endothelial growth factor (VEGF) stimulates monocyte migration through endothelial monolayers via increased integrin expression Eur. J. Cell Biol. 2000, 79, 850-857
14. Trompezinski, S.; Berthier-Vergnes, O.; Denis, A.; Schmitt, D.; Viac, J. Comparative expression of vascular endothelial growth factor family members, VEGF-B, -C and -D, by normal human keratinocytes and fibroblasts Exp. Dermatol. 2004, 13, 98-105
15. Heldin, C. H.; Westermark, B. Mechanism of action and in vivo role of platelet-derived growth factor Physiol. Rev. 1999, 79, 1283-1316
16. Stavri, G. T.; Hong, Y.; Zachary, I. C.; Breier, G.; Baskerville, P. A.; Yla-Herttuala, S.; Risau, W.; Martin, J. F.; Erusalimsky, J. D. Hypoxia and platelet-derived growth factor-BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells FEBS Lett. 1995, 358, 311-315
17. Page-McCaw, A.; Ewald, A. J.; Werb, Z. Matrix metalloproteinases and the regulation of tissue remodelling Nat. Rev. Mol. Cell Biol. 2007, 8, 221-233
18. Jung, E.; Lee, J.; Huh, S.; Hwang, H.; Kim, Y.; Kim, Y. W.; Byun, S. Y.; Park, D. Matrine inhibits PMA-induced MMP-1 expression in human dermal fibroblasts Biofactors 2008, 33, 121-128
19. Bhagavathula, N.; Warner, R. L.; DaSilva, M.; McClintock, S. D.; Barron, A.; Aslam, M. N.; Johnson, K. J.; Varani, J. A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin Wound Repair Regen. 2009, 17, 360-366
20. Swarnakar, S.; Ganguly, K.; Kundu, P.; Banerjee, A.; Maity, P.; Sharma, A. V. Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer J. Biol. Chem. 2005, 280, 9409-9415
21. Chen, C. Y.; Tai, C. J.; Cheng, J. T.; Zheng, J. J.; Chen, Y. Z.; Liu, T. Z.; Yiin, S. J.; Chern, C. L. 6-Dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5 J. Agric. Food Chem. 2010, 58, 5604-5611
22. Shoji, N.; Iwasa, A.; Takemoto, T.; Ishida, Y.; Ohizumi, Y. Cardiotonic principles of ginger (Zingiber officinale Roscoe) J. Pharm. Sci. 1982, 71, 1174-1175
23. Wang, H. M.; Chen, C. Y.; Wen, Z. H. Identifying melanogenesis inhibitors from Cinnamomum subavenium with in vitro and in vivo screening systems by targeting the human tyrosinase Exp. Dermatol. 2011, 20, 242-248
24. Wang, H. M.; Chen, C. Y.; Ho, M. L.; Chou, Y. T.; Chang, H. C.; Lee, C. H.; Wang, C. Z.; Chu, I. M. (-)- N -Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant Bioorg. Med. Chem. 2010, 18, 5241-5247
25. Wang, H. M.; Pan, J. L.; Chen, C. Y.; Chiu, C. C.; Yang, M. H.; Chang, H. W.; Chang, J. S. Identification of anti-lung cancer extract from Chlorella vulgaris C-C by antioxidant property using supercritical carbon dioxide extraction Process Biochem. 2010, 45, 1865-1872
26. Chiu, C. C.; Chou, H. L.; Wu, P. F.; Chen, H. L.; Wang, H. M.; Chen, C. Y. Bio-functional constituents from the stems of Liriodendron tulipifera Molecules 2012, 17, 4357-4372
27. Chen, B. H.; Chang, H. W.; Huang, H. M.; Chong, I. W.; Chen, J. S.; Chen, C. Y.; Wang, H. M. (-)-Anonaine induces DNA damage and inhibits growth and migration of human lung carcinoma h1299 cells J. Agric. Food Chem. 2011, 59, 2284-2290
28. Wang, H. M.; Chou, Y. T.; Wu, C. S.; Yeh, J. T. Polyester/cellulose acetate composites: preparation, characterization and biocompatible J. Appl. Polym. Sci. 2012, 126, E242-E251
29. Bertini, I.; Fragai, M.; Luchinat, C.; Melikian, M.; Mylonas, E.; Sarti, N.; Svergun, D. I. Interdomain flexibility in full-length matrix metalloproteinase-1 (MMP-1) J. Biol. Chem. 2009, 284, 12821-12828
30. Shih, M. F.; Cherng, J. Y. Potential protective effect of fresh grown unicellular green algae component (resilient factor) against PMA- and UVB-induced MMP1 expression in skin fibroblasts Eur. J. Dermatol. 2008, 18, 303-307
31. Li, F.; Nitteranon, V.; Tang, X.; Liang, J.; Zhang, G.; Parkin, K. L.; Hu, Q. In vitro antioxidant and anti-inflammatory activities of 1-dehydro-[6]-gingerdione, 6-shogaol, 6-dehydroshogaol and hexahydrocurcumin Food Chem. 2012, 135, 332-337
32. Pawar, N.; Pai, S.; Nimbalkar, M.; Dixit, G. RP-HPLC analysis of phenolic antioxidant compound 6-gingerol from different ginger cultivars Food Chem. 2011, 126, 1330-1336
33. Hsu, Y. L.; Chen, C. Y.; Hou, M. F.; Tsai, E. M.; Jong, Y. J.; Hung, C. H.; Kuo, P. L. 6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells Mol. Nutr. Food Res. 2010, 54, 1307-1317
34. Barrientos, S.; Stojadinovic, O.; Golinko, M. S.; Brem, H.; Tomic-Canic, M. Growth factors and cytokines in wound healing Wound Repair Regen. 2008, 16, 585-601
35. Lindahl, P.; Johansson, B. R.; Leveen, P.; Betsholtz, C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice Science 1997, 277, 242-245
36. Gerber, H. P.; Dixit, V.; Ferrara, N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells J. Biol. Chem. 1998, 273, 13313-13316
37. Cho, J. W.; Kang, M. C.; Lee, K. S. TGF-β1-treated ADSCs-CM promotes expression of type I collagen and MMP-1, migration of human skin fibroblasts, and wound healing in vitro and in vivo Int. J. Mol. Med. 2010, 26, 901-906
38. Muller, M.; Trocme, C.; Lardy, B.; Morel, F.; Halimi, S.; Benhamou, P. Y. Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing Diabet. Med. 2008, 25, 419-426
39. Xu, J.; Clark, R. A. A three-dimensional collagen lattice induces protein kinase C-ζ activity: role in α2 integrin and collagenase mRNA expression J. Cell Biol. 1997, 136, 473-483
40. Fineschi, S.; Reith, W.; Guerne, P. A.; Dayer, J. M.; Chizzolini, C. Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts FASEB J. 2006, 20, 562-564
41. Kim, W. S.; Park, B. S.; Sung, J. H.; Yang, J. M.; Park, S. B.; Kwak, S. J.; Park, J. S. Wound healing effect of adipose-derived stem cells: a critical role of secretory factors on human dermal fibroblasts J. Dermatol. Sci. 2007, 48, 15-24