Generation of replication-proficient influenza virus NS1 point mutants with interferon-hyperinducer phenotype

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Pérez Cidoncha, Maite ^a,e,f   Killip, Marian J ^b   Asensio, Víctor J ^c   Fernández, Yolanda ^a,e   Bengoechea, José A ^d,e,g   Randall, Richard E ^b   Ortín, Juan ^a,e  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

^c Fundació d'Investigació Sanitària de Les Illes Balears ^*  (Spain)

^d Laboratory Microbial Pathogenesis   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^g QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; INTERFERON; NONSTRUCTURAL PROTEIN 1; INS1 PROTEIN, INFLUENZA VIRUS; PRIMER DNA; VIRUS PROTEIN;

ANIMAL CELL; ANTIBODY TITER; ARTICLE; CELL SELECTION; CONTROLLED STUDY; GENE AMPLIFICATION; GENOTYPE; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; INNATE IMMUNITY; MUTAGENESIS; NONHUMAN; PHENOTYPE; POINT MUTATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA BINDING; SEQUENCE ANALYSIS; VIRION; VIRUS ISOLATION; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DOG; GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROMOTER REGION;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA PRIMERS; DOGS; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS; INTERFERONS; POINT MUTATION; PROMOTER REGIONS, GENETIC; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84902322320     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098668     Document Type: Article

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