Interaction of the influenza virus nucleoprotein with the cellular CRM1-mediated nuclear export pathway

Journal of Virology

Volumn 75, Issue 1, 2001, Pages 408-419

  Elton, D ^a   Simpson Holley, M ^a   Archer, K ^a   Medcalf, L ^a   Hallam, R ^a   McCauley, J ^a   Digard, P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; LEPTOMYCIN B; RIBONUCLEOPROTEIN; VIRUS NUCLEOPROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; INFLUENZA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; VIRUS CELL INTERACTION; VIRUS TRANSCRIPTION;

ANIMALS; CARRIER PROTEINS; CELL NUCLEUS; CHICK EMBRYO; CRICETINAE; FATTY ACIDS, UNSATURATED; KARYOPHERINS; NUCLEOCAPSID PROTEINS; NUCLEOPROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; VIRAL CORE PROTEINS; VIRAL MATRIX PROTEINS; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0034749515     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.1.408-419.2001     Document Type: Article

References (56)

1. The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP
2. Association with the cellular export receptor CRM1 mediates function and intracellular localization of Epstein-Barr virus SM protein, a regulator of gene expression
3. Migration of influenza virus-specific polypeptides from cytoplasm to nucleus of infected cells
4. Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins
5. Several protein regions contribute to determine the nuclear and cytoplasmic localization of the influenza A virus nucleopotein
6. Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: Binding of nucleoporin p54 to the rod domain of p62
7. Plasmid cDNA-directed protein synthesis in a coupled eukaryotic in vitro transcription-translation system
8. Nuclear RNA export pathways
9. Modulation of nuclear localization of the influenza virus nucleoprotein through interaction with actin filaments
10. Interactions of influenza polypeptides expressed in Xenopus oocytes
11. Evidence for specific nucleocytoplasmic transport pathways used by leucine-rich nuclear export signals
12. Oligomerization of the influenza virus nucleoprotein: Identification of positive and negative sequence elements
13. Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding
14. A complex of nuclear pore proteins required for pore function
15. CRM1 is an export receptor for leucine-rich nuclear export signals
16. The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88
17. Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes
18. CRM1 is responsible for intracellular transport mediated by the nuclear export signal
19. Monoclonal antibodies to influenza matrix protein: Detection of low levels of matrix protein on abortively infected cells
20. Influenza virus, an RNA virus, synthesizes its messenger RNA in the nucleus of infected cells
21. Determination of influenza virus proteins required for genome replication
22. Influenza virus RNA is synthesized at fixed sites in the nucleus
23. Differential phosphorylation of the nucleoprotein of influenza A viruses
24. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
25. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
26. Inhibitory effect of protein kinase C inhibitor on the replication of influenza type A virus
27. Export of importin α from the nucleus is mediated by a specific nuclear transport factor
28. Orthomyxoviridae: The viruses and their replication
29. Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import
30. Transport of incoming influenza virus nucleocapsids into the nucleus
31. Infectious entry pathway of influenza virus in a canine kidney cell line
32. Nucleocytoplasmic transport: The soluble phase
33. The temperature-sensitive lesions in two influenza A viruses defective for replicative transcription disrupt RNA binding by the nucleoprotein
34. Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids
35. Nuclear import and export of influenza virus nucleoprotein
36. Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
37. NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein
38. The influenza virus NEP (NS2 protein) mediates the nuclear export of viral ribonucleoproteins
39. Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import
40. Isolation and characterization of the ribonucleoprotein of influenza virus
41. Nuclear retention of M1 protein in a temperature-sensitive mutant of influenza (A/WSN/33) virus does not affect nuclear export of viral ribonucleoprotehns
42. NTF2 mediates nuclear import of Ran
43. Structure of influenza virus ribonucleoprotein particles. II. Purified RNA-free influenza virus ribonucleoprotein forms structures that are indistinguishable from the intact influenza virus ribonucleoprotein particles
44. Regulated production of an influenza virus spliced mRNA mediated by virus-specific products
45. Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathways
46. Exportin 1 (CRM1) is an essential nuclear export factor
47. Nuclear RNA export
48. Influenza A virus late mRNAs are specifically retained in the nucleus in the presence of a methyltransferase protein kinase inhibitor
49. The NPI-1/NPI-3 (karyopherin α) binding site on the influenza A virus nucleoprotein NP is a nonconventional nuclear localization signal
50. A classical bipartite nuclear localization signal on Thogoto and influenza A virus nucleoproteins
51. Nuclear trafficking of influenza virus ribonucleoproteins in heterokaryons
52. Hyperphosphorylation of mutant influenza virus matrix protein, M1, causes its retention in the nucleus
53. Influenza virus-specific RNA and protein syntheses in cells infected with temperature-sensitive mutants defective in the genome segment encoding nonstructural proteins
54. Molecular assembly of influenza virus: Association of the NS2 protein with virion matrix
55. Cloning and expression of influenza virus genes
56. Histones as a target for influenza virus matrix protein M1