IRF3 polymorphisms induce different innate anti-Theiler's virus immune responses in RAW264.7 macrophages

Virology

Volumn 418, Issue 1, 2011, Pages 40-48

  Moore, Tyler C ^a   Al Salleeh, Fahd M ^c   Brown, Deborah M ^a,b   Petro, Thomas M ^b,c  

^a UNIVERSITY OF NEBRASKA   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Apoptosis; B10.S; IFN ; IL 6; IRF 3; ISG56; Macrophages; SJL J; TMEV

Indexed keywords

BETA INTERFERON; CASPASE 3; DNA; INTERFERON REGULATORY FACTOR 3; INTERFERON STIMULATED GENE FACTOR 56; INTERLEUKIN 23; INTERLEUKIN 23P19; INTERLEUKIN 6; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; C57BL 10 MOUSE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; FEMALE; INNATE IMMUNITY; MACROPHAGE; MOUSE; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; STRAIN DIFFERENCE; SWISS JAMES LAMBERT MOUSE; VIRAL CLEARANCE; VIRUS REPLICATION;

ANIMALS; APOPTOSIS; CELL LINE; CYTOKINES; FEMALE; HOST-PATHOGEN INTERACTIONS; INTERFERON REGULATORY FACTOR-3; MACROPHAGES; MICE; POLYMORPHISM, GENETIC; THEILOVIRUS;

MUS; THEILER'S ENCEPHALOMYELITIS VIRUS;

EID: 80052025352     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.06.028     Document Type: Article

References (46)

1. Al-Salleeh F., Petro T.M. TLR3 and TLR7 are involved in expression of IL-23 subunits while TLR3 but not TLR7 is involved in expression of IFN-beta by Theiler's virus-infected RAW264.7 cells. Microbes Infect. 2007, 9(11):1384-1392.
2. Al-Salleeh F., Petro T.M. Promoter analysis reveals critical roles for SMAD-3 and ATF-2 in expression of IL-23 p19 in macrophages. J. Immunol. 2008, 181(7):4523-4533.
3. Aubagnac S., Brahic M., Bureau J.F. Bone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infection. J. Virol. 2002, 76(11):5807-5812.
4. Beck J.A., Lloyd S., Hafezparast M., Lennon-Pierce M., Eppig J.T., Festing M.F., Fisher E.M. Genealogies of mouse inbred strains. Nat. Genet. 2000, 24(1):23-25.
5. Bihl F., Brahic M., Bureau J.F. Two loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice. Genetics 1999, 152(1):385-392.
6. Bonetti A., Koivisto K., Pirttilä T., Elovaara I., Reunanen M., Laaksonen M., Ruutiainen J., Peltonen L., Rantamäki T., Tienari P.J. A follow-up study of chromosome 19q13 in multiple sclerosis susceptibility. J. Neuroimmunol. 2009, 208(1-2):119-124.
7. Chattopadhyay S., Marques J.T., Yamashita M., Peters K.L., Smith K., Desai A., Williams B.R.G., Sen G.C. Viral apoptosis is induced by IRF-3-mediated activation of Bax. EMBO J. 2010, 29:1762-1773.
8. Chattopadhyay S., Yamashita M., Zhang Y., Sen G.C. The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication. J. Virol. 2011, 85(8):3708-3716.
9. Dahlberg A., Auble M.R., Petro T.M. Reduced expression of IL-12 p35 by SJL/J macrophages responding to Theiler's virus infection is associated with constitutive activation of IRF-3. Virology 2006, 353(2):422-432.
10. Diebold S.S., Montoya M., Unger H., Alexopoulou L., Roy P., Haswell L.E., Al-Shamkhani A., Flavell R., Borrow P., Sousa C.R.e. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 2003, 424(6946):324-328.
11. Diebold S.S., Kaisho T., Hemmi H., Akira S., Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303(5663):1529-1531.
12. Dixit E., Boulant S., Zhang Y., Lee A.S.Y., Odendall C., Shum B., Hacohen N., Chen Z.J., Whelan S.P., Fransen M., Nibert M.L., Superti-Furga G., Kagan J.C. Peroxisomes are signaling platforms for antiviral innate immunity. Cell 2010, 141:668-681.
13. Grandvaux N., Servant M.J., tenOever B., Sen G.C., Balachandran S., Barber G.N., Lin R., Hiscott J. Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J. Virol. 2002, 76(11):5532-5539.
14. Haines J.L., Bradford Y., Garcia M.E., Reed A.D., Neumeister E., Pericak-Vance M.A., Rimmler J.B., Menold M.M., Martin E.R., Oksenberg J.R., Barcellos L.F., Lincoln R., Hauser S.L. Multiple susceptibility loci for multiple sclerosis. Hum. Mol. Genet. 2002, 11(19):2251-2256.
15. Heil F., Ahmad-Nejad P., Hemmi H., Hochrein H., Ampenberger F., Gellert T., Dietrich H., Lipford G., Takeda K., Akira S., Wagner H., Bauer S. The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur. J. Immunol. 2003, 33(11):2987-2997.
16. Heylbroeck C., Balachandran S., Servant M.J., DeLuca C., Barber G.N., Lin R., Hiscott J. The IRF-3 transcription factor mediates Sendai virus-induced apoptosis. J. Virol. 2000, 74(8):3781-3792.
17. Horng T., Barton G.M., Flavell R.A., Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002, 420(6913):329-333.
18. Hornung V., Ellegast J., Kim S., Brzozka K., Jung A., Kato H., Poeck H., Akira S., Conzelmann K.K., Schlee M., Endres S., Hartmann G. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314(5801):994-997.
19. Hou W., Kang H.S., Kim B.S. Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J. Exp. Med. 2009, 206(2):313-328.
20. Hsu Y.T., Youle R.J. Nonionic detergents induce dimerization among members of the Bcl-2 family. J. Biol. Chem. 1997, 272(21):13829-13834.
21. Johnson J., Molle C., Aksoy E., Goldman M., Goriely S., Willems F. A conventional protein kinase C inhibitor targeting IRF-3-dependent genes differentially regulates IL-12 family members. Mol. Immunol. 2011, 48(12-13):1484-1493.
22. Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., Matsui K., Uematsu S., Jung A., Kawai T., Ishii K.J., Yamaguchi O., Otsu K., Tsujimura T., Koh C.S., Reis e Sousa C., Matsuura Y., Fujita T., Akira S. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006, 441(7089):101-105.
23. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., Ishii K.J., Takeuchi O., Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 2005, 6(10):981-988.
24. Latz E., Schoenemeyer A., Visintin A., Fitzgerald K.A., Monks B.G., Knetter C.F., Lien E., Nilsen N.J., Espevik T., Golenbock D.T. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 2004, 5(2):190-198.
25. Li Y., Li C., Xue P., Zhong B., Mao A.-P., Ran Y., Chen H., Wang Y.-Y., Yang F., Shu H.-B. ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(19):7945-7950.
26. Monteyne P., Bihl F., Levillayer F., Brahic M., Bureau J.F. The Th1/Th2 balance does not account for the difference of susceptibility of mouse strains to Theiler's virus persistent infection. J. Immunol. 1999, 162(12):7330-7334.
27. Panne D. The enhanceosome. Curr. Opin. Struct. Biol. 2008, 18(2):236-242.
28. Panne D., Maniatis T., Harrison S.C. An atomic model of the interferon-beta enhanceosome. Cell 2007, 129(6):1111-1123.
29. Peters K., Chattopadhyay S., Sen G.C. IRF-3 activation by Sendai virus infection is required for cellular apoptosis and avoidance of persistence. J. Virol. 2008, 82(7):3500-3508.
30. Petro T.M. Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases. Microbes Infect. 2005, 7(2):224-232.
31. Petro T.M. ERK-MAP-kinases differentially regulate expression of IL-23 p19 compared with p40 and IFN-beta in Theiler's virus-infected RAW264.7 cells. Immunol. Lett. 2005, 97(1):47-53.
32. Pichlmair A., Schulz O., Tan C.P., Naslund T.I., Liljestrom P., Weber F., Reis e Sousa C. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314(5801):997-1001.
33. Servant M.J., Grandvaux N., Hiscott J. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochem. Pharmacol. 2002, 64(5-6):985-992.
34. Seth R.B., Sun L., Ea C.-K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-[kappa]B and IRF3. Cell 2005, 122(5):669-682.
35. Sharif-Askari E., Nakhaei P., Oliere S., Tumilasci V., Hernandez E., Wilkinson P., Lin R., Bell J., Hiscott J. Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection. Virology 2007, 365(1):20-33.
36. So E.Y., Kang M.H., Kim B.S. Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3. Glia 2006, 53(8):858-867.
37. Stawowczyk M., Van Scoy S., Kumar K.P., Reich N.C. The interferon stimulated gene 54 promotes apoptosis. J. Biol. Chem. 2011, 286(9):7257-7266.
38. Sweeney S.E., Kimbler T.B., Firestein G.S. Synoviocyte innate immune responses: II. Pivotal role of IFN regulatory factor 3. J. Immunol. 2010, 184(12):7162-7168.
39. Takahasi K., Suzuki N.N., Horiuchi M., Mori M., Suhara W., Okabe Y., Fukuhara Y., Terasawa H., Akira S., Fujita T., Inagaki F. X-ray crystal structure of IRF-3 and its functional implications. Nat. Struct. Biol. 2003, 10(11):922-927.
40. Takeuchi O., Hemmi H., Akira S. Interferon response induced by Toll-like receptor signaling. J. Endotoxin Res. 2004, 10(4):252-256.
41. Theiler M. Spontaneous encephalomyelitis of mice, a new virus disease. J. Exp. Med. 1937, 65(5):705-719.
42. Vigneau S., Rohrlich P.S., Brahic M., Bureau J.F. Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon. J. Virol. 2003, 77(10):5632-5638.
43. Virgin H.W., Wherry E.J., Ahmed R. Redefining chronic viral infection. Cell 2009, 138(1):30-50.
44. Weaver B.K., Kumar K.P., Reich N.C. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1. Mol. Cell. Biol. 1998, 18(3):1359-1368.
45. Yoneyama M., Kikuchi M., Matsumoto K., Imaizumi T., Miyagishi M., Taira K., Foy E., Loo Y.-M., Gale M., Akira S., Yonehara S., Kato A., Fujita T. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 2005, 175(5):2851-2858.
46. Zhang B., Li M., Chen L., Yang K., Shan Y., Zhu L., Sun S., Li L., Wang C. The TAK1-JNK cascade is required for IRF3 function in the innate immune response. Cell Res. 2009, 19:412-428.