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Volumn 466, Issue 6, 2014, Pages 1129-1137

Ca handling during excitation-contraction coupling in heart failure

Author keywords

Ca induced Ca release; Ryanodine receptor; Sarcoplasmic reticulum; SR Ca ATPase

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHATASE; PHOSPHODIESTERASE; PHOSPHOLAMBAN; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

EID: 84901944734     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-014-1469-3     Document Type: Review
Times cited : (77)

References (116)
  • 4
    • 0035827585 scopus 로고    scopus 로고
    • Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor)
    • Balshaw DM, Xu L, Yamaguchi N, Pasek DA, Meissner G (2001) Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor). J Biol Chem 276:20144-20153
    • (2001) J Biol Chem , vol.276 , pp. 20144-20153
    • Balshaw, D.M.1    Xu, L.2    Yamaguchi, N.3    Pasek, D.A.4    Meissner, G.5
  • 5
    • 34248597540 scopus 로고    scopus 로고
    • The mAKAP signalosome and cardiac myocyte hypertrophy
    • DOI 10.1080/15216540701358593, PII 778368024
    • Bauman AL, Michel JJ, Henson E, Dodge-Kafka KL, Kapiloff MS (2007) The mAKAP signalosome and cardiac myocyte hypertrophy. IUBMB Life 59:163-169 (Pubitemid 46752479)
    • (2007) IUBMB Life , vol.59 , Issue.3 , pp. 163-169
    • Bauman, A.L.1    Michel, J.J.C.2    Henson, E.3    Dodge-Kafka, K.L.4    Kapiloff, M.S.5
  • 6
    • 77956884740 scopus 로고    scopus 로고
    • Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling
    • Bayer JD, Narayan SM, Lalani GG, Trayanova NA (2010) Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling. Heart Rhythm 7:1093-1101
    • (2010) Heart Rhythm , vol.7 , pp. 1093-1101
    • Bayer, J.D.1    Narayan, S.M.2    Lalani, G.G.3    Trayanova, N.A.4
  • 7
    • 36849013016 scopus 로고    scopus 로고
    • Enhanced ryanodine receptor-mediated calcium leak determines reduced sarcoplasmic reticulum calcium content in chronic canine heart failure
    • DOI 10.1529/biophysj.107.114546
    • Belevych A, Kubalova Z, Terentyev D, Hamlin RL, Carnes CA, Gyorke S (2007) Enhanced ryanodine receptor-mediated calcium leak determines reduced sarcoplasmic reticulum calcium content in chronic canine heart failure. Biophys J 93:4083-4092 (Pubitemid 350223823)
    • (2007) Biophysical Journal , vol.93 , Issue.11 , pp. 4083-4092
    • Belevych, A.1    Kubalova, Z.2    Terentyev, D.3    Hamlin, R.L.4    Carnes, C.A.5    Gyorke, S.6
  • 11
    • 35448984962 scopus 로고    scopus 로고
    • Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor
    • DOI 10.1161/CIRCRESAHA.107.153007, PII 0000301220071012000013
    • Benkusky NA, Weber CS, Scherman JA, Farrell EF, Hacker TA, John MC, Powers PA, Valdivia HH (2007) Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor. Circ Res 101:819-829 (Pubitemid 350287197)
    • (2007) Circulation Research , vol.101 , Issue.8 , pp. 819-829
    • Benkusky, N.A.1    Weber, C.S.2    Scherman, J.A.3    Farrell, E.F.4    Hacker, T.A.5    John, M.C.6    Powers, P.A.7    Valdivia, H.H.8
  • 12
    • 3242692393 scopus 로고    scopus 로고
    • Macromolecular complexes regulating cardiac ryanodine receptor function
    • Bers DM (2004) Macromolecular complexes regulating cardiac ryanodine receptor function. J Mol Cell Cardiol 37:417-429
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 417-429
    • Bers, D.M.1
  • 13
    • 84858652117 scopus 로고    scopus 로고
    • Ryanodine receptor S2808 phosphorylation in heart failure: Smoking gun or red herring
    • Bers DM (2012) Ryanodine receptor S2808 phosphorylation in heart failure: smoking gun or red herring. Circ Res 110:796-799
    • (2012) Circ Res , vol.110 , pp. 796-799
    • Bers, D.M.1
  • 15
    • 0026740889 scopus 로고
    • Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with endstage heart failure caused by ischemic versus dilated cardiomyopathy
    • Brillantes AM, Allen P, Takahashi T, Izumo S, Marks AR (1992) Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with endstage heart failure caused by ischemic versus dilated cardiomyopathy. Circ Res 71:18 -26
    • (1992) Circ Res , vol.71 , pp. 18-26
    • Brillantes, A.M.1    Allen, P.2    Takahashi, T.3    Izumo, S.4    Marks, A.R.5
  • 18
    • 0027426069 scopus 로고
    • Calcium sparks: Elementary events underlying excitation-contraction coupling in heart muscle
    • Cheng H, Lederer WJ, Cannell MB (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262:740-744 (Pubitemid 23350693)
    • (1993) Science , vol.262 , Issue.5134 , pp. 740-744
    • Cheng, H.1    Lederer, W.J.2    Cannell, M.B.3
  • 19
    • 79952411074 scopus 로고    scopus 로고
    • Changes in the organization of excitation-contraction coupling structures in failing human heart
    • Crossman DJ, Ruygrok PN, Soeller C, CannellMB (2011) Changes in the organization of excitation-contraction coupling structures in failing human heart. PLoS One 6:e17901
    • (2011) PLoS One , vol.6
    • Crossman, D.J.1    Ruygrok, P.N.2    Soeller, C.3    Cannell, M.B.4
  • 20
    • 0032903877 scopus 로고    scopus 로고
    • 2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure
    • 2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure. Cardiovasc Res 41:135-146
    • (1999) Cardiovasc Res , vol.41 , pp. 135-146
    • Currie, S.1    Smith, G.L.2
  • 22
    • 70450211189 scopus 로고    scopus 로고
    • 2+ release termination by ryanodine receptor sensitization and in heart failure
    • 2+ release termination by ryanodine receptor sensitization and in heart failure. J Physiol 587:5197-5209
    • (2009) J Physiol , vol.587 , pp. 5197-5209
    • Domeier, T.L.1    Blatter, L.A.2    Zima, A.V.3
  • 23
    • 17944398302 scopus 로고
    • Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum
    • Fabiato A (1983) Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol 245:C1-C14
    • (1983) Am J Physiol , vol.245
    • Fabiato, A.1
  • 24
    • 0021914538 scopus 로고
    • Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell
    • Fabiato A (1985) Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol 85:247-289
    • (1985) J Gen Physiol , vol.85 , pp. 247-289
    • Fabiato, A.1
  • 25
    • 0141817953 scopus 로고    scopus 로고
    • Sorcin Inhibits Calcium Release and Modulates Excitation-Contraction Coupling in the Heart
    • DOI 10.1074/jbc.M305931200
    • Farrell EF, Antaramian A, Rueda A, Gomez AM, Valdivia HH (2003) Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart. J Biol Chem 278:34660-34666 (Pubitemid 37553315)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 34660-34666
    • Farrell, E.F.1    Antaramian, A.2    Rueda, A.3    Gomez, A.M.4    Valdivia, H.H.5
  • 26
    • 0027235661 scopus 로고
    • Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding
    • Feldman AM, Weinberg EO, Ray PE, Lorell BH (1993) Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res 73:184-192 (Pubitemid 23173069)
    • (1993) Circulation Research , vol.73 , Issue.1 , pp. 184-192
    • Feldman, A.M.1    Weinberg, E.O.2    Ray, P.E.3    Lorell, B.H.4
  • 28
    • 38849149701 scopus 로고    scopus 로고
    • 2+ leak in heart failure: Mere observation or functional relevance?
    • 2+ leak in heart failure: mere observation or functional relevance? Cardiovasc Res 77:302-314
    • (2008) Cardiovasc Res , vol.77 , pp. 302-314
    • George, C.H.1
  • 30
    • 0028809084 scopus 로고
    • Differential regulation of two types of intracellular calcium release channels during end-stage heart failure
    • Go LO, Moschella MC, Watras J, Handa KK, Fyfe BS, Marks AR (1995) Differential regulation of two types of intracellular calcium release channels during end-stage heart failure. J Clin Invest 95:888-894
    • (1995) J Clin Invest , vol.95 , pp. 888-894
    • Go, L.O.1    Moschella, M.C.2    Watras, J.3    Handa, K.K.4    Fyfe, B.S.5    Marks, A.R.6
  • 33
    • 77953812124 scopus 로고    scopus 로고
    • Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiacmyocytes and effects on Ca sparks
    • Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR, Bers DM (2010) Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiacmyocytes and effects on Ca sparks. Circ Res 106:1743-1752
    • (2010) Circ Res , vol.106 , pp. 1743-1752
    • Guo, T.1    Cornea, R.L.2    Huke, S.3    Camors, E.4    Yang, Y.5    Picht, E.6    Fruen, B.R.7    Bers, D.M.8
  • 36
    • 38849091360 scopus 로고    scopus 로고
    • Modulation of ryanodine receptor by luminal calcium and accessory proteins in health and cardiac disease
    • DOI 10.1093/cvr/cvm038
    • Gyorke S, Terentyev D (2008)Modulation of ryanodine receptor by luminal calcium and accessory proteins in health and cardiac disease. Cardiovasc Res 77:245-255 (Pubitemid 351197640)
    • (2008) Cardiovascular Research , vol.77 , Issue.2 , pp. 245-255
    • Gyorke, S.1    Terentyev, D.2
  • 37
    • 1942423621 scopus 로고    scopus 로고
    • The Role of Calsequestrin, Triadin, and Junctin Conferring Cardiac Ryanodine Receptor Responsiveness to Luminal Calcium
    • Gyorke I, Hester N, Jones LR, Gyorke S (2004) The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium. Biophys J 86:2121-2128 (Pubitemid 38524402)
    • (2004) Biophysical Journal , vol.86 , Issue.4 , pp. 2121-2128
    • Gyorke, I.1    Hester, N.2    Jones, L.R.3    Gyorke, S.4
  • 41
    • 0035916903 scopus 로고    scopus 로고
    • Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
    • Hobai IA, O'Rourke B (2001) Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 103:1577-1584 (Pubitemid 32226268)
    • (2001) Circulation , vol.103 , Issue.11 , pp. 1577-1584
    • Hobai, I.A.1    O'Rourke, B.2
  • 42
    • 0036514152 scopus 로고    scopus 로고
    • Regulation of calcium release by interdomain interaction within ryanodine receptors
    • Ikemoto N, Yamamoto T (2002) Regulation of calcium release by interdomain interaction within ryanodine receptors. Front Biosci 7:d671-d683
    • (2002) Front Biosci , vol.7
    • Ikemoto, N.1    Yamamoto, T.2
  • 45
    • 36749047449 scopus 로고    scopus 로고
    • 2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death
    • 2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death. Proc Natl Acad Sci U S A 104:18309-18314
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18309-18314
    • Jiang, D.1    Chen, W.2    Wang, R.3    Zhang, L.4    Chen, S.R.5
  • 49
    • 0029096774 scopus 로고
    • Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)- ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure
    • Kiss E, Ball NA, Kranias EG, Walsh RA (1995) Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)- ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure. Circ Res 77:759-764
    • (1995) Circ Res , vol.77 , pp. 759-764
    • Kiss, E.1    Ball, N.A.2    Kranias, E.G.3    Walsh, R.A.4
  • 50
    • 84862286538 scopus 로고    scopus 로고
    • Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
    • Kranias EG, Hajjar RJ (2012)Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res 110:1646-1660
    • (2012) Circ Res , vol.110 , pp. 1646-1660
    • Kranias, E.G.1    Hajjar, R.J.2
  • 52
    • 77953418093 scopus 로고    scopus 로고
    • Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure
    • Kushnir A, Shan J, Betzenhauser MJ, Reiken S, Marks AR (2010) Role of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure. Proc Natl Acad Sci U S A 107:10274-10279
    • (2010) Proc Natl Acad Sci U S a , vol.107 , pp. 10274-10279
    • Kushnir, A.1    Shan, J.2    Betzenhauser, M.J.3    Reiken, S.4    Marks, A.R.5
  • 54
    • 84871715629 scopus 로고    scopus 로고
    • Termination of calcium-induced calcium release by induction decay: An emergent property of stochastic channel gating and molecular scale architecture
    • Laver DR, Kong CH, Imtiaz MS, Cannell MB (2013) Termination of calcium-induced calcium release by induction decay: an emergent property of stochastic channel gating and molecular scale architecture. J Mol Cell Cardiol 54:98-100
    • (2013) J Mol Cell Cardiol , vol.54 , pp. 98-100
    • Laver, D.R.1    Kong, C.H.2    Imtiaz, M.S.3    Cannell, M.B.4
  • 56
    • 85047669725 scopus 로고    scopus 로고
    • Messenger RNA expression and immunological quantification of phospholamban and SR-Ca(2+)-ATPase in failing and nonfailing human hearts
    • Linck B, Boknik P, Eschenhagen T, Muller FU, Neumann J, Nose M, Jones LR, Schmitz W, Scholz H (1996) Messenger RNA expression and immunological quantification of phospholamban and SR-Ca(2+)-ATPase in failing and nonfailing human hearts. Cardiovasc Res 31:625-632
    • (1996) Cardiovasc Res , vol.31 , pp. 625-632
    • Linck, B.1    Boknik, P.2    Eschenhagen, T.3    Muller, F.U.4    Neumann, J.5    Nose, M.6    Jones, L.R.7    Schmitz, W.8    Scholz, H.9
  • 57
    • 0032054635 scopus 로고    scopus 로고
    • Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure
    • DOI 10.1006/jmcc.1997.0626
    • Lindner M, Erdmann E, Beuckelmann DJ (1998) Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure. J Mol Cell Cardiol 30:743-749 (Pubitemid 28190718)
    • (1998) Journal of Molecular and Cellular Cardiology , vol.30 , Issue.4 , pp. 743-749
    • Lindner, M.1    Erdmann, E.2    Beuckelmann, D.J.3
  • 58
    • 0034711459 scopus 로고    scopus 로고
    • Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts
    • Litwin SE, Zhang D, Bridge JH (2000) Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts. Circ Res 87:1040-1047
    • (2000) Circ Res , vol.87 , pp. 1040-1047
    • Litwin, S.E.1    Zhang, D.2    Bridge, J.H.3
  • 62
    • 0035680903 scopus 로고    scopus 로고
    • The oxidative stress hypothesis of congestive heart failure: Radical thoughts
    • DOI 10.1378/chest.120.6.2035
    • Mak S, Newton GE (2001) The oxidative stress hypothesis of congestive heart failure: radical thoughts. Chest 120:2035-2046 (Pubitemid 34053470)
    • (2001) Chest , vol.120 , Issue.6 , pp. 2035-2046
    • Mak, S.1    Newton, G.E.2
  • 63
    • 0034617175 scopus 로고    scopus 로고
    • Cardiac intracellular calcium release channels: Role in heart failure
    • Marks AR (2000) Cardiac intracellular calcium release channels: role in heart failure. Circ Res 87:8-11
    • (2000) Circ Res , vol.87 , pp. 8-11
    • Marks, A.R.1
  • 65
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101:365-376
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6    Marks, A.R.7
  • 69
    • 84875058166 scopus 로고    scopus 로고
    • Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling
    • doi:10.1016/j.bbamcr.2012.08.016
    • Niggli E, Ullrich ND, Gutierrez D, Kyrychenko S, Polakova E, Shirokova N (2012) Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling. Biochim Biophys Acta. doi:10.1016/j.bbamcr.2012.08. 016
    • (2012) Biochim Biophys Acta
    • Niggli, E.1    Ullrich, N.D.2    Gutierrez, D.3    Kyrychenko, S.4    Polakova, E.5    Shirokova, N.6
  • 70
    • 21544451389 scopus 로고    scopus 로고
    • Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure
    • DOI 10.1161/CIRCULATIONAHA.104.507921
    • Oda T, Yano M, Yamamoto T, Tokuhisa T, Okuda S, Doi M, Ohkusa T, IkedaY, Kobayashi S, Ikemoto N, Matsuzaki M (2005) Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure. Circulation 111:3400-3410 (Pubitemid 40923393)
    • (2005) Circulation , vol.111 , Issue.25 , pp. 3400-3410
    • Oda, T.1    Yano, M.2    Yamamoto, T.3    Tokuhisa, T.4    Okuda, S.5    Doi, M.6    Ohkusa, T.7    Ikeda, Y.8    Kobayashi, S.9    Ikemoto, N.10    Matsuzaki, M.11
  • 72
    • 0033583244 scopus 로고    scopus 로고
    • Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: Experimental studies
    • O'Rourke B, Kass DA, Tomaselli GF, Kaab S, Tunin R, Marban E (1999) Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure: I. Experimental studies. Circ Res 84:562-570 (Pubitemid 29138593)
    • (1999) Circulation Research , vol.84 , Issue.5 , pp. 562-570
    • O'Rourke, B.1    Kass, D.A.2    Tomaselli, G.F.3    Kaab, S.4    Tunin, R.5    Marban, E.6
  • 74
    • 0029095444 scopus 로고
    • Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy
    • Pieske B, Kretschmann B, Meyer M, Holubarsch C, Weirich J, Posival H, Minami K, Just H, Hasenfuss G (1995) Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 92:1169-1178
    • (1995) Circulation , vol.92 , pp. 1169-1178
    • Pieske, B.1    Kretschmann, B.2    Meyer, M.3    Holubarsch, C.4    Weirich, J.5    Posival, H.6    Minami, K.7    Just, H.8    Hasenfuss, G.9
  • 75
    • 0033607667 scopus 로고    scopus 로고
    • Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure
    • Pogwizd SM, Qi M, Yuan W, Samarel AM, Bers DM (1999) Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circ Res 85:1009-1019
    • (1999) Circ Res , vol.85 , pp. 1009-1019
    • Pogwizd, S.M.1    Qi, M.2    Yuan, W.3    Samarel, A.M.4    Bers, D.M.5
  • 76
    • 67650364403 scopus 로고    scopus 로고
    • 2+ binding protein: Potential roles in heart failure and arrhythmogenesis
    • 2+ binding protein: potential roles in heart failure and arrhythmogenesis. J Physiol 587:3125-3133
    • (2009) J Physiol , vol.587 , pp. 3125-3133
    • Pritchard, T.J.1    Kranias, E.G.2
  • 79
    • 81255164764 scopus 로고    scopus 로고
    • How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark?
    • Sato D, Bers DM (2011) How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark? Biophys J 101:2370-2379
    • (2011) Biophys J , vol.101 , pp. 2370-2379
    • Sato, D.1    Bers, D.M.2
  • 80
    • 0034721607 scopus 로고    scopus 로고
    • Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials
    • Schlotthauer K, Bers DM (2000) Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials. Circ Res 87:774-780
    • (2000) Circ Res , vol.87 , pp. 774-780
    • Schlotthauer, K.1    Bers, D.M.2
  • 81
    • 0032190893 scopus 로고    scopus 로고
    • Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure
    • DOI 10.1006/jmcc.1998.0748
    • Schmidt U, Hajjar RJ, Helm PA, Kim CS, Doye AA, Gwathmey JK (1998) Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure. J Mol Cell Cardiol 30:1929-1937 (Pubitemid 28495319)
    • (1998) Journal of Molecular and Cellular Cardiology , vol.30 , Issue.10 , pp. 1929-1937
    • Schmidt, U.1    Hajjar, R.J.2    Helm, P.A.3    Kim, C.S.4    Doye, A.A.5    Gwathmey, J.K.6
  • 83
    • 0028882650 scopus 로고
    • Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts
    • Schwinger RH, Bohm M, Schmidt U, Karczewski P, Bavendiek U, Flesch M, Krause EG, Erdmann E (1995) Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. Circulation 92:3220-3228
    • (1995) Circulation , vol.92 , pp. 3220-3228
    • Schwinger, R.H.1    Bohm, M.2    Schmidt, U.3    Karczewski, P.4    Bavendiek, U.5    Flesch, M.6    Krause, E.G.7    Erdmann, E.8
  • 86
    • 0033857646 scopus 로고    scopus 로고
    • Differences in mechanisms of SR dysfunction in ischemic vs. Idiopathic dilated cardiomyopathy
    • Sen L, Cui G, Fonarow GC, Laks H (2000) Differences in mechanisms of SR dysfunction in ischemic vs. idiopathic dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 279:H709-H718
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Sen, L.1    Cui, G.2    Fonarow, G.C.3    Laks, H.4
  • 89
    • 0141752833 scopus 로고    scopus 로고
    • 2+ leak in intact ventricular myocytes from rabbits in heart failure
    • 2+ leak in intact ventricular myocytes from rabbits in heart failure. Circ Res 93:592-594
    • (2003) Circ Res , vol.93 , pp. 592-594
    • Shannon, T.R.1    Pogwizd, S.M.2    Bers, D.M.3
  • 90
    • 0022921924 scopus 로고
    • Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains
    • Simmerman HK, Collins JH, Theibert JL, Wegener AD, Jones LR (1986) Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains. J Biol Chem 261:13333-13341 (Pubitemid 17006915)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.28 , pp. 13333-13341
    • Simmerman, H.K.B.1    Collins, J.H.2    Theibert, J.L.3
  • 91
    • 0028230323 scopus 로고
    • 2+
    • Sitsapesan R, Williams AJ (1994) Regulation of the gating of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by luminal Ca2+. J Membr Biol 137:215-226 (Pubitemid 24087714)
    • (1994) Journal of Membrane Biology , vol.137 , Issue.3 , pp. 215-226
    • Sitsapesan, R.1    Williams, A.J.2
  • 95
    • 0026733599 scopus 로고
    • Theory of excitation- contraction coupling in cardiac muscle
    • Stern MD (1992) Theory of excitation- contraction coupling in cardiac muscle. Biophys J 63:497-517
    • (1992) Biophys J , vol.63 , pp. 497-517
    • Stern, M.D.1
  • 96
    • 2442602416 scopus 로고    scopus 로고
    • Putting out the fire: What terminates calcium-induced calcium release in cardiac muscle?
    • DOI 10.1016/j.ceca.2004.01.013
    • Stern MD, Cheng H (2004) Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle? Cell Calcium 35:591-601 (Pubitemid 38618571)
    • (2004) Cell Calcium , vol.35 , Issue.6 , pp. 591-601
    • Stern, M.D.1    Cheng, H.2
  • 101
    • 84861587093 scopus 로고    scopus 로고
    • Ryanodine receptor phosphorylation and heart failure: Phasing out S2808 and "criminalizing" S2814
    • Valdivia HH (2012) Ryanodine receptor phosphorylation and heart failure: phasing out S2808 and "criminalizing" S2814. Circ Res 110:1398-1402
    • (2012) Circ Res , vol.110 , pp. 1398-1402
    • Valdivia, H.H.1
  • 102
  • 106
    • 1542373630 scopus 로고    scopus 로고
    • 2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6)
    • 2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). Circ Res 94:487-495
    • (2004) Circ Res , vol.94 , pp. 487-495
    • Xiao, B.1    Sutherland, C.2    Walsh, M.P.3    Chen, S.R.4
  • 107
    • 0032498185 scopus 로고    scopus 로고
    • Activation of the cardiac calcium release channel (Ryanodoine receptor) by poly-S-nitrosylation
    • DOI 10.1126/science.279.5348.234
    • Xu L, Eu JP, Meissner G, Stamler JS (1998) Activation of the cardiac calcium release channel (ryanodine receptor) by poly-Snitrosylation. Science 279:234-237 (Pubitemid 28103882)
    • (1998) Science , vol.279 , Issue.5348 , pp. 234-237
    • Xu, L.1    Eu, J.P.2    Meissner, G.3    Stamler, J.S.4
  • 112
    • 76349084460 scopus 로고    scopus 로고
    • Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice
    • Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH (2010) Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circ Res 106:354-362
    • (2010) Circ Res , vol.106 , pp. 354-362
    • Zhang, T.1    Guo, T.2    Mishra, S.3    Dalton, N.D.4    Kranias, E.G.5    Peterson, K.L.6    Bers, D.M.7    Brown, J.H.8
  • 116
    • 84892924162 scopus 로고    scopus 로고
    • Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: Analysis of recurrent cardiovascular events and mortality
    • Zsebo K, Yaroshinsky A, Rudy JJ, Wagner K, Greenberg B, Jessup M, Hajjar RJ (2014) Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circ Res 114:101-108
    • (2014) Circ Res , vol.114 , pp. 101-108
    • Zsebo, K.1    Yaroshinsky, A.2    Rudy, J.J.3    Wagner, K.4    Greenberg, B.5    Jessup, M.6    Hajjar, R.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.