메뉴 건너뛰기




Volumn 59, Issue 3, 2007, Pages 163-169

The mAKAP signalosome and cardiac myocyte hypertrophy

Author keywords

Calcineurin; Epac1; ERK5; Heart; Hypertrophy; mAKAP; NFATc; PDE4D3; PKA; Ryanodine receptor

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN BETA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN SUBUNIT; RNA; RYANODINE RECEPTOR 2; S6 KINASE; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

EID: 34248597540     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1080/15216540701358593     Document Type: Review
Times cited : (31)

References (40)
  • 1
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke, J., and Molkentin, J. D. (2006) Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 7, 589-600.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 2
    • 33846857559 scopus 로고    scopus 로고
    • Rosamond, W., Flegal, K., Friday, G., Furie, K., Go, A., Greenlund, K., Haase, N., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O'Donnell, C. J., Roger, V., Rumsfeld, J., Sorlie, P., Steinberger, J., Thom, T., Wasserthiel-Smoller, S., and Hong, Y. (2007) Heart disease and stroke statistics - 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115, e69-171.
    • Rosamond, W., Flegal, K., Friday, G., Furie, K., Go, A., Greenlund, K., Haase, N., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O'Donnell, C. J., Roger, V., Rumsfeld, J., Sorlie, P., Steinberger, J., Thom, T., Wasserthiel-Smoller, S., and Hong, Y. (2007) Heart disease and stroke statistics - 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 115, e69-171.
  • 3
    • 14644414790 scopus 로고    scopus 로고
    • Protein kinase cascades in the regulation of cardiac hypertrophy
    • Dorn, G. W., 2nd, and Force, T. (2005) Protein kinase cascades in the regulation of cardiac hypertrophy. J. Clin. Invest. 115, 527-537.
    • (2005) J. Clin. Invest , vol.115 , pp. 527-537
    • Dorn 2nd, G.W.1    Force, T.2
  • 4
    • 33847261472 scopus 로고    scopus 로고
    • Re-employment of developmental transcription factors in adult heart disease
    • Oka, T., Xu, J., and Molkentin, J. D. (2006) Re-employment of developmental transcription factors in adult heart disease. Semin. Cell Dev. Biol. 18(1), 117-131.
    • (2006) Semin. Cell Dev. Biol , vol.18 , Issue.1 , pp. 117-131
    • Oka, T.1    Xu, J.2    Molkentin, J.D.3
  • 5
    • 0037453510 scopus 로고    scopus 로고
    • Assembly of cell regulatory systems through protein interaction domains
    • Pawson, T., and Nash, P. (2003) Assembly of cell regulatory systems through protein interaction domains. Science 300, 445-452.
    • (2003) Science , vol.300 , pp. 445-452
    • Pawson, T.1    Nash, P.2
  • 6
    • 0028927472 scopus 로고
    • Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum
    • McCartney, S., Little, B. M., Langeberg, L. K., and Scott, J. D. (1995) Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. J. Biol. Chem. 270, 9327-9333.
    • (1995) J. Biol. Chem , vol.270 , pp. 9327-9333
    • McCartney, S.1    Little, B.M.2    Langeberg, L.K.3    Scott, J.D.4
  • 9
    • 12344259872 scopus 로고    scopus 로고
    • Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope
    • Pare, G. C., Easlick, J. L., Mislow, J. M., McNally, E. M., and Kapiloff, M. S. (2005) Nesprin-1alpha contributes to the targeting of mAKAP to the cardiac myocyte nuclear envelope. Exp. Cell Res. 303, 388-399.
    • (2005) Exp. Cell Res , vol.303 , pp. 388-399
    • Pare, G.C.1    Easlick, J.L.2    Mislow, J.M.3    McNally, E.M.4    Kapiloff, M.S.5
  • 10
    • 0032842848 scopus 로고    scopus 로고
    • mAKAP: An A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes
    • Kapiloff, M. S., Schillace, R. V., Westphal, A. M., and Scott, J. D. (1999) mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes. J. Cell Sci. 112, 2725-2736.
    • (1999) J. Cell Sci , vol.112 , pp. 2725-2736
    • Kapiloff, M.S.1    Schillace, R.V.2    Westphal, A.M.3    Scott, J.D.4
  • 11
    • 0034789448 scopus 로고    scopus 로고
    • mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope
    • Kapiloff, M. S., Jackson, N., and Airhart, N. (2001) mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope. J. Cell Sci. 114, 3167-3176.
    • (2001) J. Cell Sci , vol.114 , pp. 3167-3176
    • Kapiloff, M.S.1    Jackson, N.2    Airhart, N.3
  • 13
    • 30544452653 scopus 로고    scopus 로고
    • The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling
    • Pare, G. C., Bauman, A. L., McHenry, M., Michel, J. J., Dodge-Kafka, K. L., and Kapiloff, M. S. (2005) The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J. Cell Sci. 118, 5637-5646.
    • (2005) J. Cell Sci , vol.118 , pp. 5637-5646
    • Pare, G.C.1    Bauman, A.L.2    McHenry, M.3    Michel, J.J.4    Dodge-Kafka, K.L.5    Kapiloff, M.S.6
  • 14
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx, S. O., Reiken, S., Hisamatsu, Y., Jayaraman, T., Burkhoff, D., Rosemblit, N., and Marks, A. R. (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101, 365-376.
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6    Marks, A.R.7
  • 15
    • 0042090358 scopus 로고    scopus 로고
    • Targeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptor
    • Ruehr, M. L., Russell, M. A., Ferguson, D. G., Bhat, M., Ma, J., Damron, D. S., Scott, J. D., and Bond, M. (2003) Targeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptor. J. Biol. Chem. 278, 24831-24836.
    • (2003) J. Biol. Chem , vol.278 , pp. 24831-24836
    • Ruehr, M.L.1    Russell, M.A.2    Ferguson, D.G.3    Bhat, M.4    Ma, J.5    Damron, D.S.6    Scott, J.D.7    Bond, M.8
  • 17
    • 0032572584 scopus 로고    scopus 로고
    • A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart
    • Yang, J., Drazba, J. A., Ferguson, D. G., and Bond, M. (1998) A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart. J. Cell Biol. 142, 511-522.
    • (1998) J. Cell Biol , vol.142 , pp. 511-522
    • Yang, J.1    Drazba, J.A.2    Ferguson, D.G.3    Bond, M.4
  • 18
    • 33846140462 scopus 로고    scopus 로고
    • KASH-domain proteins in nuclear migration, anchorage and other processes
    • Wilhelmsen, K., Ketema, M., Truong, H., and Sonnenberg, A. (2006) KASH-domain proteins in nuclear migration, anchorage and other processes. J. Cell Sci. 119, 5021-5029.
    • (2006) J. Cell Sci , vol.119 , pp. 5021-5029
    • Wilhelmsen, K.1    Ketema, M.2    Truong, H.3    Sonnenberg, A.4
  • 19
    • 33749003191 scopus 로고    scopus 로고
    • SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton
    • Tzur, Y. B., Wilson, K. L., and Gruenbaum, Y. (2006) SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton. Nat. Rev. Mol. Cell Biol. 7, 782-788.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 782-788
    • Tzur, Y.B.1    Wilson, K.L.2    Gruenbaum, Y.3
  • 21
    • 0035794551 scopus 로고    scopus 로고
    • A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes
    • Newlon, M. G., Roy, M., Morikis, D., Carr, D. W., Westphal, R., Scott, J. D., and Jennings, P. A. (2001) A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. EMBO J. 20, 1651-1662.
    • (2001) EMBO J , vol.20 , pp. 1651-1662
    • Newlon, M.G.1    Roy, M.2    Morikis, D.3    Carr, D.W.4    Westphal, R.5    Scott, J.D.6    Jennings, P.A.7
  • 22
    • 0034731395 scopus 로고    scopus 로고
    • Selectivity and regulation of A-kinase anchoring proteins in the heart. The role of autophosphorylation of the type II regulatory subunit of cAMP-dependent protein kinase
    • Zakhary, D. R., Fink, M. A., Ruehr, M. L., and Bond, M. (2000) Selectivity and regulation of A-kinase anchoring proteins in the heart. The role of autophosphorylation of the type II regulatory subunit of cAMP-dependent protein kinase. J. Biol. Chem. 275, 41389-41395.
    • (2000) J. Biol. Chem , vol.275 , pp. 41389-41395
    • Zakhary, D.R.1    Fink, M.A.2    Ruehr, M.L.3    Bond, M.4
  • 23
    • 3242716356 scopus 로고    scopus 로고
    • A-kinase anchoring protein targeting of protein kinase A in the heart
    • Ruehr, M. L., Russell, M. A., and Bond, M. (2004) A-kinase anchoring protein targeting of protein kinase A in the heart. J. Mol. Cell. Cardiol. 37, 653-665.
    • (2004) J. Mol. Cell. Cardiol , vol.37 , pp. 653-665
    • Ruehr, M.L.1    Russell, M.A.2    Bond, M.3
  • 24
    • 0142259450 scopus 로고    scopus 로고
    • PDE4: Arrested at the border
    • Brunton, L. L. (2003) PDE4: arrested at the border. Sci. STKE PE44.
    • (2003) Sci. STKE
    • Brunton, L.L.1
  • 25
    • 33744981419 scopus 로고    scopus 로고
    • Phosphodiesterases and compartmentalized cAMP signalling in the heart
    • Zaccolo, M. (2006) Phosphodiesterases and compartmentalized cAMP signalling in the heart. Eur. J. Cell Biol. 85, 693-697.
    • (2006) Eur. J. Cell Biol , vol.85 , pp. 693-697
    • Zaccolo, M.1
  • 26
    • 33748562850 scopus 로고    scopus 로고
    • Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling
    • Lynch, M. J., Hill, E. V., and Houslay, M. D. (2006) Intracellular targeting of phosphodiesterase-4 underpins compartmentalized cAMP signaling. Curr. Top. Dev. Biol. 75, 225-259.
    • (2006) Curr. Top. Dev. Biol , vol.75 , pp. 225-259
    • Lynch, M.J.1    Hill, E.V.2    Houslay, M.D.3
  • 27
    • 4344594414 scopus 로고    scopus 로고
    • PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex
    • Carlisle Michel, J. J., Dodge, K. L., Wong, W., Mayer, N. C., Langeberg, L. K., and Scott, J. D. (2004) PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex. Biochem. J. 381, 587-592.
    • (2004) Biochem. J , vol.381 , pp. 587-592
    • Carlisle Michel, J.J.1    Dodge, K.L.2    Wong, W.3    Mayer, N.C.4    Langeberg, L.K.5    Scott, J.D.6
  • 28
    • 33747792064 scopus 로고    scopus 로고
    • MAPK signalling: ERK5 versus ERK1/2
    • Nishimoto, S., and Nishida, E. (2006) MAPK signalling: ERK5 versus ERK1/2. EMBO Rep. 7, 782-786.
    • (2006) EMBO Rep , vol.7 , pp. 782-786
    • Nishimoto, S.1    Nishida, E.2
  • 29
    • 33751241720 scopus 로고    scopus 로고
    • Epac proteins: Multi-purpose cAMP targets
    • Bos, J. L. (2006) Epac proteins: multi-purpose cAMP targets. Trends Biochem. Sci. 31, 680-686.
    • (2006) Trends Biochem. Sci , vol.31 , pp. 680-686
    • Bos, J.L.1
  • 31
    • 0037742556 scopus 로고    scopus 로고
    • Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart
    • Yin, F., Li, P., Zheng, M., Chen, L., Xu, Q., Chen, K., Wang, Y. Y., Zhang, Y. Y., and Han, C. (2003) Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. J. Biol. Chem. 278, 21070-21075.
    • (2003) J. Biol. Chem , vol.278 , pp. 21070-21075
    • Yin, F.1    Li, P.2    Zheng, M.3    Chen, L.4    Xu, Q.5    Chen, K.6    Wang, Y.Y.7    Zhang, Y.Y.8    Han, C.9
  • 32
    • 0035355360 scopus 로고    scopus 로고
    • Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
    • Nicol, R. L., Frey, N., Pearson, G., Cobb, M., Richardson, J., and Olson, E. N. (2001) Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J. 20, 2757-2767.
    • (2001) EMBO J , vol.20 , pp. 2757-2767
    • Nicol, R.L.1    Frey, N.2    Pearson, G.3    Cobb, M.4    Richardson, J.5    Olson, E.N.6
  • 34
    • 15544374098 scopus 로고    scopus 로고
    • Intracellular calcium release and cardiac disease
    • Wehrens, X. H., Lehnart, S. E., and Marks, A. R. (2005) Intracellular calcium release and cardiac disease. Annu. Rev. Physiol. 67, 69-98.
    • (2005) Annu. Rev. Physiol , vol.67 , pp. 69-98
    • Wehrens, X.H.1    Lehnart, S.E.2    Marks, A.R.3
  • 35
    • 33746826872 scopus 로고    scopus 로고
    • 2+ store throughout cardiac myocyte
    • 2+ store throughout cardiac myocyte. Circ. Res. 99, 283-291.
    • (2006) Circ. Res , vol.99 , pp. 283-291
    • Wu, X.1    Bers, D.M.2
  • 38
    • 33846460041 scopus 로고    scopus 로고
    • Agonists and antagonists of the cardiac ryanodine receptor: Potential therapeutic agents?
    • Dulhunty, A. F., Beard, N. A., Pouliquin, P., and Casarotto, M. G. (2007) Agonists and antagonists of the cardiac ryanodine receptor: Potential therapeutic agents? Pharmacol. Ther. 113, 247-263.
    • (2007) Pharmacol. Ther , vol.113 , pp. 247-263
    • Dulhunty, A.F.1    Beard, N.A.2    Pouliquin, P.3    Casarotto, M.G.4
  • 39
    • 33646924842 scopus 로고    scopus 로고
    • Cardiac ryanodine receptor phosphorylation: Target sites and functional consequences
    • Bers, D. M. (2006) Cardiac ryanodine receptor phosphorylation: target sites and functional consequences. Biochem. J. 396, e1-3.
    • (2006) Biochem. J , vol.396
    • Bers, D.M.1
  • 40
    • 4444382387 scopus 로고    scopus 로고
    • Calcium-calcineurin signaling in the regulation of cardiac hypertrophy
    • Wilkins, B. J., and Molkentin, J. D. (2004) Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem. Biophys. Res. Commun. 322, 1178-1191.
    • (2004) Biochem. Biophys. Res. Commun , vol.322 , pp. 1178-1191
    • Wilkins, B.J.1    Molkentin, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.