Reduced Ca2+-sensitivity of SERCA 2a in failing human myocardium due to reduced serin-16 phospholamban phoshorylation

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 3, 1999, Pages 479-491

  Schwinger, Robert H G ^a   Münch, Götz ^a   Bölck, Brigit ^a   Karczewski, Peter ^b   Krause, Ernst Georg ^b   Erdmann, Erland ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Ca2+ transporting ATPase; Force frequency relationship; Heart failure; Human myocardium; Phospholamban; Sarcoplasmic reticulum

Indexed keywords

CALCIUM ION; CALSEQUESTRIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLAMBAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SERCA 2A; THREONINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; HEART FAILURE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; STIMULATION;

EID: 0033105384     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0897     Document Type: Article

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