Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca2+ release in heart failure

Cardiovascular Research

Volumn 87, Issue 4, 2010, Pages 609-617

  Ono, Makoto ^a   Yano, Masafumi ^a   Hino, Akihiro ^a   Suetomi, Takeshi ^a   Xu, Xiaojuan ^a   Susa, Takehisa ^a   Uchinoumi, Hitoshi ^a   Tateishi, Hiroki ^a   Oda, Tetsuro ^a   Okuda, Shinichi ^a   Doi, Masahiro ^a   Kobayashi, Shigeki ^a   Yamamoto, Takeshi ^a   Koseki, Noritaka ^b   Kyushiki, Hiroyuki ^b   Ikemoto, Noriaki ^c,d   Matsuzaki, Masunori ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^c BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calcium; Calmodulin; Heart failure; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

CALCIUM ION; CALMODULIN; DANTROLENE; FK 506 BINDING PROTEIN; RYANODINE RECEPTOR 2; SAPONIN; TACROLIMUS;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CELL VACUOLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; COVALENT BOND; CROSS LINKING; EXPERIMENTAL DOG; HEART FAILURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM SIGNALING; CALMODULIN; CARDIAC PACING, ARTIFICIAL; DANTROLENE; DISEASE MODELS, ANIMAL; DOGS; EXCITATION CONTRACTION COUPLING; HEART FAILURE; MICROSCOPY, CONFOCAL; MYOCARDIUM; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TACROLIMUS; TACROLIMUS BINDING PROTEINS;

EID: 77955880918     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq108     Document Type: Article

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