Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure

Circulation Research

Volumn 91, Issue 11, 2002, Pages 1015-1022

  Jiang, Ming Tao ^a,b   Lokuta, Andrew J ^a   Farrell, Emily F ^a   Wolff, Matthew R ^a   Haworth, Robert A ^a   Valdivia, Héctor H ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Heart failure; Protein kinase A; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLAMBAN; RYANODINE RECEPTOR; CALCIUM BINDING PROTEIN; FK 506 BINDING PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TACROLIMUS BINDING PROTEIN 1B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CALCIUM CONDUCTANCE; CALCIUM TRANSPORT; CONTROLLED STUDY; DOG; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; TACHYCARDIA; ANIMAL; BINDING COMPETITION; CALCIUM SIGNALING; COMPARATIVE STUDY; CONGESTIVE HEART FAILURE; DISEASE MODEL; HEART MUSCLE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; DOGS; HEART FAILURE, CONGESTIVE; HUMANS; MYOCARDIUM; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TACROLIMUS BINDING PROTEINS;

EID: 0037195427     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000043663.08689.05     Document Type: Article

References (25)

1. Fabiato A. Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol. 1985;85:247-289.
2. Bers D. Excitation Contraction Coupling and Cardiac Contractile Force. 2nd Ed. The Netherlands: Kluwer Academic Publishers; 2000.
3. O'Rouke B, Kass DA, Tomaselli GF, Kaab S, Tunin R, Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: Experimental studies. Circ Res. 1999;84:562-570.
4. Beuckelman DJ, Nabauer M, Erdman E. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation. 1992;85:1046-1055.
5. Gómez AM, Valdivia HH, Cheng H, Lederer M, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science. 1997;276:800-806.
6. 2+ content in isolated failing and nonfailing human myocardium. Circ Res. 1999;85:38-46.
7. 2+ transient of failing human ventricular myocytes. Circ Res. 1999;84:435-444.
8. 2+ exchange activity in canine pacing-induced heart failure. Circ Res. 2000;87:690-698.
9. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts. Cell. 2000;101:365-376.
10. 2+ release in heart failure. Cardiovasc Res. 2000;48:323-331.
11. 2+ release channel closure in rat heart. J Physiol. 1997;500:343-354.
12. Wolff MR, Whitesell LF, Moss RL. Calcium sensitivity of isometric tension is increased in canine experimental heart failure. Circ Res. 1995;76:781-789.
13. 2+-resistant myocytes from the adult rat. J Mol Cell Cardiol. 1980;12:715-723.
14. Lokuta AJ, Rogers TB, Lederer WJ, Valdivia HH. Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. J Physiol (Lond). 1995;487:609-622.
15. Jiang MT, Narayanan N. Effect of aging on phosphorylation of phospholamban and calcium transport in rat cardiac sarcoplasmic reticulum. Mech Ageing Dev. 1990;54:87-101.
16. Lokuta AJ, Meyers MB, Sander PR, Fishman G, and Valdivia HH. Modulation of cardiac ryanodine receptors by sorcin. J Biol Chem. 1997;272:25333-38.
17. 2+ and phosphorylation. Science. 1995;267:1997-2000.
18. Phillips RM, Narayan P, Gomez AM, Dilly K, Jones LR, Lederer WJ, Altschuld RA. Sarcoplasmic reticulum in heart failure: Central player or bystander? Cardiovasc Res. 1998;37:346-351.
19. 2+ release in heart. Science. 1993;260:807-809.
20. 2+-release channels from cardiac muscle. Circ Res. 1996;78:990-997.
21. Jeyakumar LH, Ballester L, Cheng DS, McIntyre JO, Chang P, Olivey HE, Rollins-Smith L, Barnett JV, Murray K, Xin HB, Fleischer S. FKBP binding characteristics of cardiac microsomes from diverse vertebrates. Biochem Biophys Res Commun. 2001;281:979-986.
22. Brodde OE. β1- and β2-adrenoceptors in the human heart: Properties, function, and alterations in chronic heart failure. Pharmacol Rev. 1991;43:203-242.
23. Bers DM. Cardiac excitation-contraction coupling. Nature. 2002;415:198-205.
24. Trafford AW, Diaz ME, O'Neill SC, Eisner DA. Integrative analysis of calcium signalling in cardiac muscle. Front Biosci. 2002;7:D843-852.
25. Li Y, Kranias EG, Mignery GA, Bers DM. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res. 2002;90:309-316.