Cellular and molecular determinants of altered Ca2+ handling in the failing rabbit heart: Primary defects in SR Ca2+ uptake and release mechanisms

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 3, 2007, Pages

  Armoundas, Antonis A ^a   Rose, Jochen ^b   Aggarwal, Rajesh ^c   Stuyvers, Bruno D ^d   O'Rourke, Brian ^b   Kass, David A ^b   Marbán, Eduardo ^b   Shorofsky, Stephen R ^c   Tomaselli, Gordon F ^b,f   Balke, C William ^e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

^e UNIVERSITY OF KENTUCKY   (United States)

^f JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Calcium; Ion channels; Pacing tachycardia; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ALPHA 1C ADRENERGIC RECEPTOR; CALCIUM ION; MESSENGER RNA; PHOSPHOLAMBAN; RYANODINE RECEPTOR;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; FEMALE; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CONTRACTILE FORCE; HEART PACING; HEART RATE; HEART REPOLARIZATION; MALE; MEMBRANE POTENTIAL; MUSCLE CELL; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; RABBIT; SARCOPLASMIC RETICULUM; TACHYCARDIA; UPREGULATION;

ABDOMEN; ANIMALS; CALCIUM; CALCIUM SIGNALING; DISEASE MODELS, ANIMAL; HEART FAILURE, CONGESTIVE; MUSCLE, SKELETAL; PACEMAKER, ARTIFICIAL; RABBITS;

EID: 33847748590     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00525.2006     Document Type: Article

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