-
1
-
-
84866929338
-
Redox signaling in cardiac physiology and pathology
-
Burgoyne J.R., Mongue-Din H., Eaton P., Shah A.M. Redox signaling in cardiac physiology and pathology. Circ Res 2012, 111:1091-1106.
-
(2012)
Circ Res
, vol.111
, pp. 1091-1106
-
-
Burgoyne, J.R.1
Mongue-Din, H.2
Eaton, P.3
Shah, A.M.4
-
2
-
-
84874081484
-
NADPH oxidases in heart failure: poachers or gamekeepers?
-
Zhang M., Perino A., Ghigo A., Hirsch E., Shah A.M. NADPH oxidases in heart failure: poachers or gamekeepers?. Antioxid Redox Signal 2013, 18:1024-1041.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1024-1041
-
-
Zhang, M.1
Perino, A.2
Ghigo, A.3
Hirsch, E.4
Shah, A.M.5
-
3
-
-
0037426373
-
Functional consequences of endothelial nitric oxide synthase uncoupling in congestive cardiac failure
-
Dixon L.J., Morgan D.R., Hughes S.M., McGrath L.T., El-Sherbeeny N.A., Plumb R.D., et al. Functional consequences of endothelial nitric oxide synthase uncoupling in congestive cardiac failure. Circulation 2003, 107:1725-1728.
-
(2003)
Circulation
, vol.107
, pp. 1725-1728
-
-
Dixon, L.J.1
Morgan, D.R.2
Hughes, S.M.3
McGrath, L.T.4
El-Sherbeeny, N.A.5
Plumb, R.D.6
-
4
-
-
0033520357
-
Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure
-
Ekelund U.E., Harrison R.W., Shokek O., Thakkar R.N., Tunin R.S., Senzaki H., et al. Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. Circ Res 1999, 85:437-445.
-
(1999)
Circ Res
, vol.85
, pp. 437-445
-
-
Ekelund, U.E.1
Harrison, R.W.2
Shokek, O.3
Thakkar, R.N.4
Tunin, R.S.5
Senzaki, H.6
-
5
-
-
0033588198
-
Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
-
Ide T., Tsutsui H., Kinugawa S., Utsumi H., Kang D., Hattori N., et al. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ Res 1999, 85:357-363.
-
(1999)
Circ Res
, vol.85
, pp. 357-363
-
-
Ide, T.1
Tsutsui, H.2
Kinugawa, S.3
Utsumi, H.4
Kang, D.5
Hattori, N.6
-
6
-
-
24144464489
-
Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources
-
Adam-Vizi V. Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. Antioxid Redox Signal 2005, 7:1140-1149.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1140-1149
-
-
Adam-Vizi, V.1
-
7
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens J.F. Mitochondrial formation of reactive oxygen species. J Physiol 2003, 552:335-344.
-
(2003)
J Physiol
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
8
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban R.S., Nemoto S., Finkel T. Mitochondria, oxidants, and aging. Cell 2005, 120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
9
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. Biochem J 2009, 417:1-13.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
10
-
-
84856556021
-
There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells
-
Brown G.C., Borutaite V. There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells. Mitochondrion 2012, 12:1-4.
-
(2012)
Mitochondrion
, vol.12
, pp. 1-4
-
-
Brown, G.C.1
Borutaite, V.2
-
11
-
-
79954694973
-
Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure
-
Dai D.F., Johnson S.C., Villarin J.J., Chin M.T., Nieves-Cintron M., Chen T., et al. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circ Res 2011, 108:837-846.
-
(2011)
Circ Res
, vol.108
, pp. 837-846
-
-
Dai, D.F.1
Johnson, S.C.2
Villarin, J.J.3
Chin, M.T.4
Nieves-Cintron, M.5
Chen, T.6
-
12
-
-
47649122637
-
Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy
-
Moens A.L., Takimoto E., Tocchetti C.G., Chakir K., Bedja D., Cormaci G., et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 2008, 117:2626-2636.
-
(2008)
Circulation
, vol.117
, pp. 2626-2636
-
-
Moens, A.L.1
Takimoto, E.2
Tocchetti, C.G.3
Chakir, K.4
Bedja, D.5
Cormaci, G.6
-
13
-
-
20944445197
-
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
-
Takimoto E., Champion H.C., Li M., Ren S., Rodriguez E.R., Tavazzi B., et al. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest 2005, 115:1221-1231.
-
(2005)
J Clin Invest
, vol.115
, pp. 1221-1231
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Ren, S.4
Rodriguez, E.R.5
Tavazzi, B.6
-
14
-
-
0037154308
-
Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
-
Bendall J.K., Cave A.C., Heymes C., Gall N., Shah A.M. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 2002, 105:293-296.
-
(2002)
Circulation
, vol.105
, pp. 293-296
-
-
Bendall, J.K.1
Cave, A.C.2
Heymes, C.3
Gall, N.4
Shah, A.M.5
-
15
-
-
84555188518
-
Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress
-
Dai D.F., Hsieh E.J., Liu Y., Chen T., Beyer R.P., Chin M.T., et al. Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress. Cardiovasc Res 2012, 93:79-88.
-
(2012)
Cardiovasc Res
, vol.93
, pp. 79-88
-
-
Dai, D.F.1
Hsieh, E.J.2
Liu, Y.3
Chen, T.4
Beyer, R.P.5
Chin, M.T.6
-
16
-
-
78049434938
-
Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
-
Dai D.F., Chen T., Wanagat J., Laflamme M., Marcinek D.J., Emond M.J., et al. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria. Aging Cell 2010, 9:536-544.
-
(2010)
Aging Cell
, vol.9
, pp. 536-544
-
-
Dai, D.F.1
Chen, T.2
Wanagat, J.3
Laflamme, M.4
Marcinek, D.J.5
Emond, M.J.6
-
17
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 2005, 308:1909-1911.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
-
18
-
-
84859884412
-
Mitochondria and cardiovascular aging
-
Dai D.F., Rabinovitch P.S., Ungvari Z. Mitochondria and cardiovascular aging. Circ Res 2012, 110:1109-1124.
-
(2012)
Circ Res
, vol.110
, pp. 1109-1124
-
-
Dai, D.F.1
Rabinovitch, P.S.2
Ungvari, Z.3
-
19
-
-
79959525058
-
Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy
-
Dai D.F., Chen T., Szeto H., Nieves-Cintron M., Kutyavin V., Santana L.F., et al. Mitochondrial targeted antioxidant Peptide ameliorates hypertensive cardiomyopathy. J Am Coll Cardiol 2011, 58:73-82.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 73-82
-
-
Dai, D.F.1
Chen, T.2
Szeto, H.3
Nieves-Cintron, M.4
Kutyavin, V.5
Santana, L.F.6
-
20
-
-
79959492723
-
Targeting mitochondrial oxidative stress in heart failure: throttling the afterburner
-
Maack C., Böhm M. Targeting mitochondrial oxidative stress in heart failure: throttling the afterburner. J Am Coll Cardiol 2011, 58:83-86.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 83-86
-
-
Maack, C.1
Böhm, M.2
-
21
-
-
77953809992
-
Redox-optimized ROS balance: a unifying hypothesis
-
Aon M.A., Cortassa S., O'Rourke B. Redox-optimized ROS balance: a unifying hypothesis. Biochim Biophys Acta 2010, 1797:865-877.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 865-877
-
-
Aon, M.A.1
Cortassa, S.2
O'Rourke, B.3
-
22
-
-
84890254589
-
Redox-Optimized ROS Balance and the relationship between mitochondrial respiration and ROS
-
Cortassa S., O'Rourke B., Aon M.A. Redox-Optimized ROS Balance and the relationship between mitochondrial respiration and ROS. Biochim Biophys Acta 1837, 2013:287-295.
-
(1837)
Biochim Biophys Acta
, vol.2013
, pp. 287-295
-
-
Cortassa, S.1
O'Rourke, B.2
Aon, M.A.3
-
23
-
-
84882973495
-
A computational model of reactive oxygen species and redox balance in cardiac mitochondria
-
Gauthier L.D., Greenstein J.L., Cortassa S., O'Rourke B., Winslow R.L. A computational model of reactive oxygen species and redox balance in cardiac mitochondria. Biophys J 2013, 105:1045-1056.
-
(2013)
Biophys J
, vol.105
, pp. 1045-1056
-
-
Gauthier, L.D.1
Greenstein, J.L.2
Cortassa, S.3
O'Rourke, B.4
Winslow, R.L.5
-
24
-
-
0034596947
-
Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
-
Zorov D.B., Filburn C.R., Klotz L.O., Zweier J.L., Sollott S.J. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med 2000, 192:1001-1014.
-
(2000)
J Exp Med
, vol.192
, pp. 1001-1014
-
-
Zorov, D.B.1
Filburn, C.R.2
Klotz, L.O.3
Zweier, J.L.4
Sollott, S.J.5
-
25
-
-
0242582202
-
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
-
Aon M.A., Cortassa S., Marban E., O'Rourke B. Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J Biol Chem 2003, 278:44735-44744.
-
(2003)
J Biol Chem
, vol.278
, pp. 44735-44744
-
-
Aon, M.A.1
Cortassa, S.2
Marban, E.3
O'Rourke, B.4
-
26
-
-
20944442518
-
Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II
-
Kimura S., Zhang G.X., Nishiyama A., Shokoji T., Yao L., Fan Y.Y., et al. Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II. Hypertension 2005, 45:860-866.
-
(2005)
Hypertension
, vol.45
, pp. 860-866
-
-
Kimura, S.1
Zhang, G.X.2
Nishiyama, A.3
Shokoji, T.4
Yao, L.5
Fan, Y.Y.6
-
28
-
-
67349244350
-
Domestication of the cardiac mitochondrion for energy conversion
-
Balaban R.S. Domestication of the cardiac mitochondrion for energy conversion. J Mol Cell Cardiol 2009, 46:832-841.
-
(2009)
J Mol Cell Cardiol
, vol.46
, pp. 832-841
-
-
Balaban, R.S.1
-
30
-
-
79951975935
-
The mitochondrial respiratory chain
-
Rich P.R., Marechal A. The mitochondrial respiratory chain. Essays Biochem 2010, 47:1-23.
-
(2010)
Essays Biochem
, vol.47
, pp. 1-23
-
-
Rich, P.R.1
Marechal, A.2
-
31
-
-
36949083936
-
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
-
Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 1961, 191:144-148.
-
(1961)
Nature
, vol.191
, pp. 144-148
-
-
Mitchell, P.1
-
32
-
-
33746824336
-
Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes
-
Maack C., Cortassa S., Aon M.A., Ganesan A.N., Liu T., O'Rourke B. Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes. Circ Res 2006, 99:172-182.
-
(2006)
Circ Res
, vol.99
, pp. 172-182
-
-
Maack, C.1
Cortassa, S.2
Aon, M.A.3
Ganesan, A.N.4
Liu, T.5
O'Rourke, B.6
-
33
-
-
84877307518
-
Calcium release microdomains and mitochondria
-
Kohlhaas M., Maack C. Calcium release microdomains and mitochondria. Cardiovasc Res 2013, 98:259-268.
-
(2013)
Cardiovasc Res
, vol.98
, pp. 259-268
-
-
Kohlhaas, M.1
Maack, C.2
-
34
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Kirichok Y., Krapivinsky G., Clapham D.E. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 2004, 427:360-364.
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
35
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
Baughman J.M., Perocchi F., Girgis H.S., Plovanich M., Belcher-Timme C.A., Sancak Y., et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 2011, 476:341-345.
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
-
36
-
-
80051936634
-
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
-
De Stefani D., Raffaello A., Teardo E., Szabo I., Rizzuto R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 2011, 476:336-340.
-
(2011)
Nature
, vol.476
, pp. 336-340
-
-
De Stefani, D.1
Raffaello, A.2
Teardo, E.3
Szabo, I.4
Rizzuto, R.5
-
37
-
-
84879520256
-
Mitochondrial calcium uptake
-
Williams G.S., Boyman L., Chikando A.C., Khairallah R.J., Lederer W.J. Mitochondrial calcium uptake. Proc Natl Acad Sci U S A 2013, 110:10479-10486.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 10479-10486
-
-
Williams, G.S.1
Boyman, L.2
Chikando, A.C.3
Khairallah, R.J.4
Lederer, W.J.5
-
38
-
-
84864645903
-
Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes
-
Drago I., De Stefani D., Rizzuto R., Pozzan T. Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes. Proc Natl Acad Sci U S A 2012, 109:12986-12991.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12986-12991
-
-
Drago, I.1
De Stefani, D.2
Rizzuto, R.3
Pozzan, T.4
-
39
-
-
84873410873
-
Measuring local gradients of intramitochondrial [Ca2+] in cardiac myocytes during sarcoplasmic reticulum Ca2+ release
-
Lu X., Ginsburg K.S., Kettlewell S., Bossuyt J., Smith G.L., Bers D.M. Measuring local gradients of intramitochondrial [Ca2+] in cardiac myocytes during sarcoplasmic reticulum Ca2+ release. Circ Res 2013, 112:424-431.
-
(2013)
Circ Res
, vol.112
, pp. 424-431
-
-
Lu, X.1
Ginsburg, K.S.2
Kettlewell, S.3
Bossuyt, J.4
Smith, G.L.5
Bers, D.M.6
-
40
-
-
33644847375
-
Microdomains of intracellular Ca2+: molecular determinants and functional consequences
-
Rizzuto R., Pozzan T. Microdomains of intracellular Ca2+: molecular determinants and functional consequences. Physiol Rev 2006, 86:369-408.
-
(2006)
Physiol Rev
, vol.86
, pp. 369-408
-
-
Rizzuto, R.1
Pozzan, T.2
-
41
-
-
66849134930
-
Three-dimensional electron microscopy reveals new details of membrane systems for Ca2+ signaling in the heart
-
Hayashi T., Martone M.E., Yu Z., Thor A., Doi M., Holst M.J., et al. Three-dimensional electron microscopy reveals new details of membrane systems for Ca2+ signaling in the heart. J Cell Sci 2009, 122:1005-1013.
-
(2009)
J Cell Sci
, vol.122
, pp. 1005-1013
-
-
Hayashi, T.1
Martone, M.E.2
Yu, Z.3
Thor, A.4
Doi, M.5
Holst, M.J.6
-
43
-
-
84872680832
-
SR and mitochondria: calcium cross-talk between kissing cousins
-
Dorn G.W., Maack C. SR and mitochondria: calcium cross-talk between kissing cousins. J Mol Cell Cardiol 2013, 55:42-49.
-
(2013)
J Mol Cell Cardiol
, vol.55
, pp. 42-49
-
-
Dorn, G.W.1
Maack, C.2
-
44
-
-
0017406503
-
Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
-
Cadenas E., Boveris A., Ragan C.I., Stoppani A.O. Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Biophys 1977, 180:248-257.
-
(1977)
Arch Biochem Biophys
, vol.180
, pp. 248-257
-
-
Cadenas, E.1
Boveris, A.2
Ragan, C.I.3
Stoppani, A.O.4
-
45
-
-
0021996572
-
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
-
Turrens J.F., Alexandre A., Lehninger A.L. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch Biochem Biophys 1985, 237:408-414.
-
(1985)
Arch Biochem Biophys
, vol.237
, pp. 408-414
-
-
Turrens, J.F.1
Alexandre, A.2
Lehninger, A.L.3
-
46
-
-
0029765443
-
Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
-
Skulachev V.P. Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q Rev Biophys 1996, 29:169-202.
-
(1996)
Q Rev Biophys
, vol.29
, pp. 169-202
-
-
Skulachev, V.P.1
-
47
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov S.S., Skulachev V.P., Starkov A.A. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 1997, 416:15-18.
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
48
-
-
0042433242
-
Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state
-
Starkov A.A., Fiskum G. Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state. J Neurochem 2003, 86:1101-1107.
-
(2003)
J Neurochem
, vol.86
, pp. 1101-1107
-
-
Starkov, A.A.1
Fiskum, G.2
-
49
-
-
25144476923
-
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
-
Brand M.D., Esteves T.C. Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2005, 2:85-93.
-
(2005)
Cell Metab
, vol.2
, pp. 85-93
-
-
Brand, M.D.1
Esteves, T.C.2
-
51
-
-
37549068090
-
NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences
-
Ying W. NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid Redox Signal 2008, 10:179-206.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 179-206
-
-
Ying, W.1
-
52
-
-
0037423881
-
Is depressed myocyte contractility centrally involved in heart failure?
-
Houser S.R., Margulies K.B. Is depressed myocyte contractility centrally involved in heart failure?. Circ Res 2003, 92:350-358.
-
(2003)
Circ Res
, vol.92
, pp. 350-358
-
-
Houser, S.R.1
Margulies, K.B.2
-
53
-
-
33845296446
-
Altered cardiac myocyte Ca regulation in heart failure
-
Bers D.M. Altered cardiac myocyte Ca regulation in heart failure. Physiology (Bethesda) 2006, 21:380-387.
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 380-387
-
-
Bers, D.M.1
-
54
-
-
84878396026
-
Novel aspects of excitation-contraction coupling in heart failure
-
Neef S., Maier L.S. Novel aspects of excitation-contraction coupling in heart failure. Basic Res Cardiol 2013, 108:360.
-
(2013)
Basic Res Cardiol
, vol.108
, pp. 360
-
-
Neef, S.1
Maier, L.S.2
-
55
-
-
0037188622
-
Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged
-
Despa S., Islam M.A., Weber C.R., Pogwizd S.M., Bers D.M. Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged. Circulation 2002, 105:2543-2548.
-
(2002)
Circulation
, vol.105
, pp. 2543-2548
-
-
Despa, S.1
Islam, M.A.2
Weber, C.R.3
Pogwizd, S.M.4
Bers, D.M.5
-
57
-
-
84880324424
-
Na(+) transport in the normal and failing heart - remember the balance
-
Despa S., Bers D.M. Na(+) transport in the normal and failing heart - remember the balance. J Mol Cell Cardiol 2013, 61:2-10.
-
(2013)
J Mol Cell Cardiol
, vol.61
, pp. 2-10
-
-
Despa, S.1
Bers, D.M.2
-
58
-
-
0037488534
-
Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts
-
Armoundas A.A., Hobai I.A., Tomaselli G.F., Winslow R.L., O'Rourke B. Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circ Res 2003, 93:46-53.
-
(2003)
Circ Res
, vol.93
, pp. 46-53
-
-
Armoundas, A.A.1
Hobai, I.A.2
Tomaselli, G.F.3
Winslow, R.L.4
O'Rourke, B.5
-
59
-
-
0242298644
-
Dynamic regulation of sodium/calcium exchange function in human heart failure
-
Weber C.R., Piacentino V., Houser S.R., Bers D.M. Dynamic regulation of sodium/calcium exchange function in human heart failure. Circulation 2003, 108:2224-2229.
-
(2003)
Circulation
, vol.108
, pp. 2224-2229
-
-
Weber, C.R.1
Piacentino, V.2
Houser, S.R.3
Bers, D.M.4
-
60
-
-
0037376146
-
Calcium entry via Na/Ca exchange during the action potential directly contributes to contraction of failing human ventricular myocytes
-
Weisser-Thomas J., Piacentino V., Gaughan J.P., Margulies K., Houser S.R. Calcium entry via Na/Ca exchange during the action potential directly contributes to contraction of failing human ventricular myocytes. Cardiovasc Res 2003, 57:974-985.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 974-985
-
-
Weisser-Thomas, J.1
Piacentino, V.2
Gaughan, J.P.3
Margulies, K.4
Houser, S.R.5
-
62
-
-
76249133414
-
NCLX is an essential component of mitochondrial Na+/Ca2+ exchange
-
Palty R., Silverman W.F., Hershfinkel M., Caporale T., Sensi S.L., Parnis J., et al. NCLX is an essential component of mitochondrial Na+/Ca2+ exchange. Proc Natl Acad Sci U S A 2010, 107:436-441.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 436-441
-
-
Palty, R.1
Silverman, W.F.2
Hershfinkel, M.3
Caporale, T.4
Sensi, S.L.5
Parnis, J.6
-
63
-
-
78650090134
-
2+ influx in cardiac myocytes
-
2+ influx in cardiac myocytes. Circulation 2010, 122:2273-2280.
-
(2010)
Circulation
, vol.122
, pp. 2273-2280
-
-
Kohlhaas, M.1
Maack, C.2
-
64
-
-
53549099939
-
Enhancing mitochondrial Ca2+ uptake in myocytes from failing hearts restores energy supply and demand matching
-
Liu T., O'Rourke B. Enhancing mitochondrial Ca2+ uptake in myocytes from failing hearts restores energy supply and demand matching. Circ Res 2008, 103:279-288.
-
(2008)
Circ Res
, vol.103
, pp. 279-288
-
-
Liu, T.1
O'Rourke, B.2
-
65
-
-
33947239659
-
The failing heart - an engine out of fuel
-
Neubauer S. The failing heart - an engine out of fuel. N Engl J Med 2007, 356:1140-1151.
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
66
-
-
14144256552
-
ATP flux through creatine kinase in the normal, stressed, and failing human heart
-
Weiss R.G., Gerstenblith G., Bottomley P.A. ATP flux through creatine kinase in the normal, stressed, and failing human heart. Proc Natl Acad Sci U S A 2005, 102:808-813.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 808-813
-
-
Weiss, R.G.1
Gerstenblith, G.2
Bottomley, P.A.3
-
67
-
-
84890779283
-
An integrated mitochondrial ROS production and scavenging model: implications for heart failure
-
Gauthier L.D., Greenstein J.L., O'Rourke B., Winslow R.L. An integrated mitochondrial ROS production and scavenging model: implications for heart failure. Biophys J 2013, 105:2832-2842.
-
(2013)
Biophys J
, vol.105
, pp. 2832-2842
-
-
Gauthier, L.D.1
Greenstein, J.L.2
O'Rourke, B.3
Winslow, R.L.4
-
68
-
-
77957272433
-
NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart
-
Kuroda J., Ago T., Matsushima S., Zhai P., Schneider M.D., Sadoshima J. NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart. Proc Natl Acad Sci U S A 2010, 107:15565-15570.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15565-15570
-
-
Kuroda, J.1
Ago, T.2
Matsushima, S.3
Zhai, P.4
Schneider, M.D.5
Sadoshima, J.6
-
69
-
-
60349109393
-
Characteristics and function of cardiac mitochondrial nitric oxide synthase
-
Dedkova E.N., Blatter L.A. Characteristics and function of cardiac mitochondrial nitric oxide synthase. J Physiol 2009, 587:851-872.
-
(2009)
J Physiol
, vol.587
, pp. 851-872
-
-
Dedkova, E.N.1
Blatter, L.A.2
-
70
-
-
74049129002
-
Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload
-
Kaludercic N., Takimoto E., Nagayama T., Feng N., Lai E.W., Bedja D., et al. Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circ Res 2010, 106:193-202.
-
(2010)
Circ Res
, vol.106
, pp. 193-202
-
-
Kaludercic, N.1
Takimoto, E.2
Nagayama, T.3
Feng, N.4
Lai, E.W.5
Bedja, D.6
-
71
-
-
62249115660
-
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase
-
Di Lisa F., Kaludercic N., Carpi A., Menabo R., Giorgio M. Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase. Basic Res Cardiol 2009, 104:131-139.
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 131-139
-
-
Di Lisa, F.1
Kaludercic, N.2
Carpi, A.3
Menabo, R.4
Giorgio, M.5
-
72
-
-
84874093502
-
Redox regulation of sodium and calcium handling
-
Wagner S., Rokita A.G., Anderson M.E., Maier L.S. Redox regulation of sodium and calcium handling. Antioxid Redox Signal 2013, 18:1063-1077.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1063-1077
-
-
Wagner, S.1
Rokita, A.G.2
Anderson, M.E.3
Maier, L.S.4
-
73
-
-
84872865639
-
Oxidative stress and sarcomeric proteins
-
Steinberg S.F. Oxidative stress and sarcomeric proteins. Circ Res 2013, 112:393-405.
-
(2013)
Circ Res
, vol.112
, pp. 393-405
-
-
Steinberg, S.F.1
-
74
-
-
33745198418
-
Redox regulation of cardiac calcium channels and transporters
-
Zima A.V., Blatter L.A. Redox regulation of cardiac calcium channels and transporters. Cardiovasc Res 2006, 71:310-321.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 310-321
-
-
Zima, A.V.1
Blatter, L.A.2
-
75
-
-
33746922414
-
Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation
-
Brennan J.P., Bardswell S.C., Burgoyne J.R., Fuller W., Schroder E., Wait R., et al. Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation. J Biol Chem 2006, 281:21827-21836.
-
(2006)
J Biol Chem
, vol.281
, pp. 21827-21836
-
-
Brennan, J.P.1
Bardswell, S.C.2
Burgoyne, J.R.3
Fuller, W.4
Schroder, E.5
Wait, R.6
-
76
-
-
0024724936
-
2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain
-
2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain. Proc Natl Acad Sci U S A 1989, 86:6758-6762.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 6758-6762
-
-
Gopalakrishna, R.1
Anderson, W.B.2
-
77
-
-
42949085382
-
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
-
Erickson J.R., Joiner M.L., Guan X., Kutschke W., Yang J., Oddis C.V., et al. A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 2008, 133:462-474.
-
(2008)
Cell
, vol.133
, pp. 462-474
-
-
Erickson, J.R.1
Joiner, M.L.2
Guan, X.3
Kutschke, W.4
Yang, J.5
Oddis, C.V.6
-
82
-
-
77957838101
-
A beta(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
-
Hund T.J., Koval O.M., Li J., Wright P.J., Qian L., Snyder J.S., et al. A beta(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice. J Clin Invest 2010, 120:3508-3519.
-
(2010)
J Clin Invest
, vol.120
, pp. 3508-3519
-
-
Hund, T.J.1
Koval, O.M.2
Li, J.3
Wright, P.J.4
Qian, L.5
Snyder, J.S.6
-
83
-
-
79952772425
-
Reactive oxygen species-activated Ca/calmodulin kinase IIdelta is required for late I(Na) augmentation leading to cellular Na and Ca overload
-
Wagner S., Ruff H.M., Weber S.L., Bellmann S., Sowa T., Schulte T., et al. Reactive oxygen species-activated Ca/calmodulin kinase IIdelta is required for late I(Na) augmentation leading to cellular Na and Ca overload. Circ Res 2011, 108:555-565.
-
(2011)
Circ Res
, vol.108
, pp. 555-565
-
-
Wagner, S.1
Ruff, H.M.2
Weber, S.L.3
Bellmann, S.4
Sowa, T.5
Schulte, T.6
-
84
-
-
0027198602
-
Measurement of Na(+)-K+ pump current in isolated rabbit ventricular myocytes using the whole-cell voltage-clamp technique Inhibition of the pump by oxidant stress
-
Shattock M.J., Matsuura H. Measurement of Na(+)-K+ pump current in isolated rabbit ventricular myocytes using the whole-cell voltage-clamp technique Inhibition of the pump by oxidant stress. Circ Res 1993, 72:91-101.
-
(1993)
Circ Res
, vol.72
, pp. 91-101
-
-
Shattock, M.J.1
Matsuura, H.2
-
86
-
-
0033609455
-
Effect of beta-blockers on free radical-induced cardiac contractile dysfunction
-
Flesch M., Maack C., Cremers B., Bäumer A.T., Südkamp M., Böhm M. Effect of beta-blockers on free radical-induced cardiac contractile dysfunction. Circulation 1999, 100:346-353.
-
(1999)
Circulation
, vol.100
, pp. 346-353
-
-
Flesch, M.1
Maack, C.2
Cremers, B.3
Bäumer, A.T.4
Südkamp, M.5
Böhm, M.6
-
87
-
-
0031015476
-
Hydroxyl radical inhibits sarcoplasmic reticulum Ca(2+)-ATPase function by direct attack on the ATP binding site
-
Xu K.Y., Zweier J.L., Becker L.C. Hydroxyl radical inhibits sarcoplasmic reticulum Ca(2+)-ATPase function by direct attack on the ATP binding site. Circ Res 1997, 80:76-81.
-
(1997)
Circ Res
, vol.80
, pp. 76-81
-
-
Xu, K.Y.1
Zweier, J.L.2
Becker, L.C.3
-
88
-
-
0032498185
-
Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation
-
Xu L., Eu J.P., Meissner G., Stamler J.S. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 1998, 279:234-237.
-
(1998)
Science
, vol.279
, pp. 234-237
-
-
Xu, L.1
Eu, J.P.2
Meissner, G.3
Stamler, J.S.4
-
89
-
-
33750740174
-
2+ exchange in ventricular myocytes
-
2+ exchange in ventricular myocytes. Am J Physiol 1996, 271:H823-H833.
-
(1996)
Am J Physiol
, vol.271
-
-
Goldhaber, J.I.1
-
90
-
-
84861360208
-
Interplay of defective excitation-contraction coupling, energy starvation, and oxidative stress in heart failure
-
Kohlhaas M., Maack C. Interplay of defective excitation-contraction coupling, energy starvation, and oxidative stress in heart failure. Trends Cardiovasc Med 2011, 21:69-73.
-
(2011)
Trends Cardiovasc Med
, vol.21
, pp. 69-73
-
-
Kohlhaas, M.1
Maack, C.2
-
91
-
-
33746088001
-
Trends in prevalence and outcome of heart failure with preserved ejection fraction
-
Owan T.E., Hodge D.O., Herges R.M., Jacobsen S.J., Roger V.L., Redfield M.M. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med 2006, 355:251-259.
-
(2006)
N Engl J Med
, vol.355
, pp. 251-259
-
-
Owan, T.E.1
Hodge, D.O.2
Herges, R.M.3
Jacobsen, S.J.4
Roger, V.L.5
Redfield, M.M.6
-
92
-
-
34548525319
-
How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology
-
Paulus W.J., Tschöpe C., Sanderson J.E., Rusconi C., Flachskampf F.A., Rademakers F.E., et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J 2007, 28:2539-2550.
-
(2007)
Eur Heart J
, vol.28
, pp. 2539-2550
-
-
Paulus, W.J.1
Tschöpe, C.2
Sanderson, J.E.3
Rusconi, C.4
Flachskampf, F.A.5
Rademakers, F.E.6
-
93
-
-
0037321921
-
Prevalence of left ventricular diastolic dysfunction in the community. Results from a Doppler echocardiographic-based survey of a population sample
-
Fischer M., Baessler A., Hense H.W., Hengstenberg C., Muscholl M., Holmer S., et al. Prevalence of left ventricular diastolic dysfunction in the community. Results from a Doppler echocardiographic-based survey of a population sample. Eur Heart J 2003, 24:320-328.
-
(2003)
Eur Heart J
, vol.24
, pp. 320-328
-
-
Fischer, M.1
Baessler, A.2
Hense, H.W.3
Hengstenberg, C.4
Muscholl, M.5
Holmer, S.6
-
94
-
-
84879748718
-
A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
-
Paulus W.J., Tschope C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol 2013, 62:263-271.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 263-271
-
-
Paulus, W.J.1
Tschope, C.2
-
95
-
-
77956572071
-
Mitochondria in the diabetic heart
-
Bugger H., Abel E.D. Mitochondria in the diabetic heart. Cardiovasc Res 2010, 88:229-240.
-
(2010)
Cardiovasc Res
, vol.88
, pp. 229-240
-
-
Bugger, H.1
Abel, E.D.2
-
96
-
-
84881320396
-
Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies
-
Ilkun O., Boudina S. Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies. Curr Pharm Des 2013, 19:4806-4817.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 4806-4817
-
-
Ilkun, O.1
Boudina, S.2
-
97
-
-
70350445742
-
Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart
-
Anderson E.J., Kypson A.P., Rodriguez E., Anderson C.A., Lehr E.J., Neufer P.D. Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 2009, 54:1891-1898.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 1891-1898
-
-
Anderson, E.J.1
Kypson, A.P.2
Rodriguez, E.3
Anderson, C.A.4
Lehr, E.J.5
Neufer, P.D.6
-
98
-
-
63649106676
-
Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
-
Boudina S., Bugger H., Sena S., O'Neill B.T., Zaha V.G., Ilkun O., et al. Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. Circulation 2009, 119:1272-1283.
-
(2009)
Circulation
, vol.119
, pp. 1272-1283
-
-
Boudina, S.1
Bugger, H.2
Sena, S.3
O'Neill, B.T.4
Zaha, V.G.5
Ilkun, O.6
-
99
-
-
34548848059
-
Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins
-
Boudina S., Sena S., Theobald H., Sheng X., Wright J.J., Hu X.X., et al. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 2007, 56:2457-2466.
-
(2007)
Diabetes
, vol.56
, pp. 2457-2466
-
-
Boudina, S.1
Sena, S.2
Theobald, H.3
Sheng, X.4
Wright, J.J.5
Hu, X.X.6
-
100
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
St-Pierre J., Buckingham J.A., Roebuck S.J., Brand M.D. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J Biol Chem 2002, 277:44784-44790.
-
(2002)
J Biol Chem
, vol.277
, pp. 44784-44790
-
-
St-Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
101
-
-
77949419999
-
Uncoupling protein-2 modulates myocardial excitation-contraction coupling
-
Turner J.D., Gaspers L.D., Wang G., Thomas A.P. Uncoupling protein-2 modulates myocardial excitation-contraction coupling. Circ Res 2010, 106:730-738.
-
(2010)
Circ Res
, vol.106
, pp. 730-738
-
-
Turner, J.D.1
Gaspers, L.D.2
Wang, G.3
Thomas, A.P.4
-
102
-
-
31044442642
-
The mitochondrial origin of postischemic arrhythmias
-
Akar F.G., Aon M.A., Tomaselli G.F., O'Rourke B. The mitochondrial origin of postischemic arrhythmias. J Clin Invest 2005, 115:3527-3535.
-
(2005)
J Clin Invest
, vol.115
, pp. 3527-3535
-
-
Akar, F.G.1
Aon, M.A.2
Tomaselli, G.F.3
O'Rourke, B.4
-
103
-
-
55649118870
-
Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts
-
Slodzinski M.K., Aon M.A., O'Rourke B. Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts. J Mol Cell Cardiol 2008, 45:650-660.
-
(2008)
J Mol Cell Cardiol
, vol.45
, pp. 650-660
-
-
Slodzinski, M.K.1
Aon, M.A.2
O'Rourke, B.3
-
105
-
-
0035000183
-
ATP consumption by uncoupled mitochondria activates sarcolemmal K(ATP) channels in cardiac myocytes
-
Sasaki N., Sato T., Marban E., O'Rourke B. ATP consumption by uncoupled mitochondria activates sarcolemmal K(ATP) channels in cardiac myocytes. Am J Physiol Heart Circ Physiol 2001, 280:H1882-H1888.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Sasaki, N.1
Sato, T.2
Marban, E.3
O'Rourke, B.4
-
106
-
-
15844404722
-
Biochemistry: a pore way to die
-
Halestrap A. Biochemistry: a pore way to die. Nature 2005, 434:578-579.
-
(2005)
Nature
, vol.434
, pp. 578-579
-
-
Halestrap, A.1
-
107
-
-
0022970945
-
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium
-
Murry C.E., Jennings R.B., Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986, 74:1124-1136.
-
(1986)
Circulation
, vol.74
, pp. 1124-1136
-
-
Murry, C.E.1
Jennings, R.B.2
Reimer, K.A.3
-
108
-
-
0030888801
-
Oxygen radicals can induce preconditioning in rabbit hearts
-
Tritto I., D'Andrea D., Eramo N., Scognamiglio A., De Simone C., Violante A., et al. Oxygen radicals can induce preconditioning in rabbit hearts. Circ Res 1997, 80:743-748.
-
(1997)
Circ Res
, vol.80
, pp. 743-748
-
-
Tritto, I.1
D'Andrea, D.2
Eramo, N.3
Scognamiglio, A.4
De Simone, C.5
Violante, A.6
-
109
-
-
0032541173
-
Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes
-
Vanden Hoek T.L., Becker L.B., Shao Z., Li C., Schumacker P.T. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J Biol Chem 1998, 273:18092-18098.
-
(1998)
J Biol Chem
, vol.273
, pp. 18092-18098
-
-
Vanden Hoek, T.L.1
Becker, L.B.2
Shao, Z.3
Li, C.4
Schumacker, P.T.5
-
110
-
-
1542343927
-
+ channels and their role in cardioprotection
-
+ channels and their role in cardioprotection. Circ Res 2004, 94:420-432.
-
(2004)
Circ Res
, vol.94
, pp. 420-432
-
-
O'Rourke, B.1
-
111
-
-
84864880941
-
Mitochondrial ROMK channel is a molecular component of mitoK(ATP)
-
Foster D.B., Ho A.S., Rucker J., Garlid A.O., Chen L., Sidor A., et al. Mitochondrial ROMK channel is a molecular component of mitoK(ATP). Circ Res 2012, 111:446-454.
-
(2012)
Circ Res
, vol.111
, pp. 446-454
-
-
Foster, D.B.1
Ho, A.S.2
Rucker, J.3
Garlid, A.O.4
Chen, L.5
Sidor, A.6
-
112
-
-
52449115978
-
Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT
-
Costa A.D., Garlid K.D. Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT. Am J Physiol Heart Circ Physiol 2008, 295:H874-H882.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Costa, A.D.1
Garlid, K.D.2
-
113
-
-
85047692700
-
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
-
Juhaszova M., Zorov D.B., Kim S.H., Pepe S., Fu Q., Fishbein K.W., et al. Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest 2004, 113:1535-1549.
-
(2004)
J Clin Invest
, vol.113
, pp. 1535-1549
-
-
Juhaszova, M.1
Zorov, D.B.2
Kim, S.H.3
Pepe, S.4
Fu, Q.5
Fishbein, K.W.6
-
114
-
-
48249109117
-
Effect of cyclosporine on reperfusion injury in acute myocardial infarction
-
Piot C., Croisille P., Staat P., Thibault H., Rioufol G., Mewton N., et al. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med 2008, 359:473-481.
-
(2008)
N Engl J Med
, vol.359
, pp. 473-481
-
-
Piot, C.1
Croisille, P.2
Staat, P.3
Thibault, H.4
Rioufol, G.5
Mewton, N.6
-
115
-
-
40749130846
-
Long-term benefit of postconditioning
-
Thibault H., Piot C., Staat P., Bontemps L., Sportouch C., Rioufol G., et al. Long-term benefit of postconditioning. Circulation 2008, 117:1037-1044.
-
(2008)
Circulation
, vol.117
, pp. 1037-1044
-
-
Thibault, H.1
Piot, C.2
Staat, P.3
Bontemps, L.4
Sportouch, C.5
Rioufol, G.6
-
116
-
-
26944445765
-
Postconditioning the human heart
-
Staat P., Rioufol G., Piot C., Cottin Y., Cung T.T., L'Huillier I., et al. Postconditioning the human heart. Circulation 2005, 112:2143-2148.
-
(2005)
Circulation
, vol.112
, pp. 2143-2148
-
-
Staat, P.1
Rioufol, G.2
Piot, C.3
Cottin, Y.4
Cung, T.T.5
L'Huillier, I.6
-
117
-
-
84882265326
-
Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial
-
Thielmann M., Kottenberg E., Kleinbongard P., Wendt D., Gedik N., Pasa S., et al. Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial. Lancet 2013, 382:597-604.
-
(2013)
Lancet
, vol.382
, pp. 597-604
-
-
Thielmann, M.1
Kottenberg, E.2
Kleinbongard, P.3
Wendt, D.4
Gedik, N.5
Pasa, S.6
-
118
-
-
84872088738
-
Cardioprotection: chances and challenges of its translation to the clinic
-
Heusch G. Cardioprotection: chances and challenges of its translation to the clinic. Lancet 2013, 381:166-175.
-
(2013)
Lancet
, vol.381
, pp. 166-175
-
-
Heusch, G.1
-
119
-
-
18244376587
-
Triggering mitochondrial radical release: a new function for NADPH oxidases
-
Brandes R.P. Triggering mitochondrial radical release: a new function for NADPH oxidases. Hypertension 2005, 45:847-848.
-
(2005)
Hypertension
, vol.45
, pp. 847-848
-
-
Brandes, R.P.1
-
120
-
-
0141841614
-
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
-
Maack C., Kartes T., Kilter H., Schäfers H.J., Nickenig G., Böhm M., et al. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation 2003, 108:1567-1574.
-
(2003)
Circulation
, vol.108
, pp. 1567-1574
-
-
Maack, C.1
Kartes, T.2
Kilter, H.3
Schäfers, H.J.4
Nickenig, G.5
Böhm, M.6
-
121
-
-
70350135479
-
Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning
-
Maack C., Dabew E.R., Hohl M., Schäfers H.J., Böhm M. Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning. Circ Res 2009, 105:811-817.
-
(2009)
Circ Res
, vol.105
, pp. 811-817
-
-
Maack, C.1
Dabew, E.R.2
Hohl, M.3
Schäfers, H.J.4
Böhm, M.5
-
122
-
-
0030222249
-
Myocardial infarct size is smaller in dogs with pacing-induced heart failure
-
Hoskins D.E., Ignasiak D.P., Saganek L.J., Gallagher K.P., Peterson J.T. Myocardial infarct size is smaller in dogs with pacing-induced heart failure. Cardiovasc Res 1996, 32:238-247.
-
(1996)
Cardiovasc Res
, vol.32
, pp. 238-247
-
-
Hoskins, D.E.1
Ignasiak, D.P.2
Saganek, L.J.3
Gallagher, K.P.4
Peterson, J.T.5
-
123
-
-
33646679144
-
Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice
-
Matsushima S., Ide T., Yamato M., Matsusaka H., Hattori F., Ikeuchi M., et al. Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 2006, 113:1779-1786.
-
(2006)
Circulation
, vol.113
, pp. 1779-1786
-
-
Matsushima, S.1
Ide, T.2
Yamato, M.3
Matsusaka, H.4
Hattori, F.5
Ikeuchi, M.6
-
124
-
-
84887454400
-
Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides
-
Dai D.F., Hsieh E.J., Chen T., Menendez L.G., Basisty N.B., Tsai L., et al. Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides. Circ Heart Fail 2013, 6:1067-1076.
-
(2013)
Circ Heart Fail
, vol.6
, pp. 1067-1076
-
-
Dai, D.F.1
Hsieh, E.J.2
Chen, T.3
Menendez, L.G.4
Basisty, N.B.5
Tsai, L.6
-
125
-
-
79955391768
-
Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy
-
Abel E.D., Doenst T. Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy. Cardiovasc Res 2011, 90:234-242.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 234-242
-
-
Abel, E.D.1
Doenst, T.2
-
126
-
-
79955451479
-
Metabolic remodelling in human heart failure
-
Tuunanen H., Knuuti J. Metabolic remodelling in human heart failure. Cardiovasc Res 2011, 90:251-257.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 251-257
-
-
Tuunanen, H.1
Knuuti, J.2
-
127
-
-
84865847066
-
Metabolic remodeling in the hypertrophic heart: fuel for thought
-
Chatham J.C., Young M.E. Metabolic remodeling in the hypertrophic heart: fuel for thought. Circ Res 2012, 111:666-668.
-
(2012)
Circ Res
, vol.111
, pp. 666-668
-
-
Chatham, J.C.1
Young, M.E.2
-
128
-
-
84865863479
-
Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy
-
Kolwicz S.C., Olson D.P., Marney L.C., Garcia-Menendez L., Synovec R.E., Tian R. Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy. Circ Res 2012, 111:728-738.
-
(2012)
Circ Res
, vol.111
, pp. 728-738
-
-
Kolwicz, S.C.1
Olson, D.P.2
Marney, L.C.3
Garcia-Menendez, L.4
Synovec, R.E.5
Tian, R.6
-
129
-
-
84875218521
-
Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice
-
Lygate C.A., Aksentijevic D., Dawson D., Ten Hove M., Phillips D., de Bono J.P., et al. Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice. Circ Res 2013, 112:945-955.
-
(2013)
Circ Res
, vol.112
, pp. 945-955
-
-
Lygate, C.A.1
Aksentijevic, D.2
Dawson, D.3
Ten Hove, M.4
Phillips, D.5
de Bono, J.P.6
-
130
-
-
84879478027
-
Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes
-
Sag C.M., Wagner S., Maier L.S. Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes. Free Radic Biol Med 2013, 63:338-349.
-
(2013)
Free Radic Biol Med
, vol.63
, pp. 338-349
-
-
Sag, C.M.1
Wagner, S.2
Maier, L.S.3
-
131
-
-
44649184557
-
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy
-
Ago T., Liu T., Zhai P., Chen W., Li H., Molkentin J.D., et al. A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. Cell 2008, 133:978-993.
-
(2008)
Cell
, vol.133
, pp. 978-993
-
-
Ago, T.1
Liu, T.2
Zhai, P.3
Chen, W.4
Li, H.5
Molkentin, J.D.6
-
132
-
-
0034688195
-
Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf S., Dagenais G., Pogue J., Bosch J., Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000, 342:154-160.
-
(2000)
N Engl J Med
, vol.342
, pp. 154-160
-
-
Yusuf, S.1
Dagenais, G.2
Pogue, J.3
Bosch, J.4
Sleight, P.5
-
133
-
-
78149239505
-
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
-
Zhang M., Brewer A.C., Schroder K., Santos C.X., Grieve D.J., Wang M., et al. NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis. Proc Natl Acad Sci U S A 2010, 107:18121-18126.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18121-18126
-
-
Zhang, M.1
Brewer, A.C.2
Schroder, K.3
Santos, C.X.4
Grieve, D.J.5
Wang, M.6
-
134
-
-
29344446328
-
Targeting antioxidants to mitochondria: a new therapeutic direction
-
Sheu S.S., Nauduri D., Anders M.W. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta 2006, 1762:256-265.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 256-265
-
-
Sheu, S.S.1
Nauduri, D.2
Anders, M.W.3
-
135
-
-
84880253528
-
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
-
Chouchani E.T., Methner C., Nadtochiy S.M., Logan A., Pell V.R., Ding S., et al. Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med 2013, 19:753-759.
-
(2013)
Nat Med
, vol.19
, pp. 753-759
-
-
Chouchani, E.T.1
Methner, C.2
Nadtochiy, S.M.3
Logan, A.4
Pell, V.R.5
Ding, S.6
-
136
-
-
21744450416
-
Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury
-
Adlam V.J., Harrison J.C., Porteous C.M., James A.M., Smith R.A., Murphy M.P., et al. Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J 2005, 19:1088-1095.
-
(2005)
FASEB J
, vol.19
, pp. 1088-1095
-
-
Adlam, V.J.1
Harrison, J.C.2
Porteous, C.M.3
James, A.M.4
Smith, R.A.5
Murphy, M.P.6
-
137
-
-
84888012439
-
Cationic antioxidants as a powerful tool against mitochondrial oxidative stress
-
Skulachev V.P. Cationic antioxidants as a powerful tool against mitochondrial oxidative stress. Biochem Biophys Res Commun 2013, 441:275-279.
-
(2013)
Biochem Biophys Res Commun
, vol.441
, pp. 275-279
-
-
Skulachev, V.P.1
-
138
-
-
84861841056
-
Mitochondrial pharmacology
-
Smith R.A., Hartley R.C., Cocheme H.M., Murphy M.P. Mitochondrial pharmacology. Trends Pharmacol Sci 2012, 33:341-352.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 341-352
-
-
Smith, R.A.1
Hartley, R.C.2
Cocheme, H.M.3
Murphy, M.P.4
-
139
-
-
84897457350
-
First-in-class cardiolipin therapeutic to restore mitochondrial bioenergetics
-
Szeto H.H. First-in-class cardiolipin therapeutic to restore mitochondrial bioenergetics. Br J Pharmacol 2014, 171:2029-2050.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 2029-2050
-
-
Szeto, H.H.1
-
140
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties
-
Kelso G.F., Porteous C.M., Coulter C.V., Hughes G., Porteous W.K., Ledgerwood E.C., et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem 2001, 276:4588-4596.
-
(2001)
J Biol Chem
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
Hughes, G.4
Porteous, W.K.5
Ledgerwood, E.C.6
-
141
-
-
68549112975
-
Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy
-
Graham D., Huynh N.N., Hamilton C.A., Beattie E., Smith R.A., Cocheme H.M., et al. Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension 2009, 54:322-328.
-
(2009)
Hypertension
, vol.54
, pp. 322-328
-
-
Graham, D.1
Huynh, N.N.2
Hamilton, C.A.3
Beattie, E.4
Smith, R.A.5
Cocheme, H.M.6
-
143
-
-
77955095876
-
Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: prevention by the targeted antioxidant MitoQ
-
Vergeade A., Mulder P., Vendeville-Dehaudt C., Estour F., Fortin D., Ventura-Clapier R., et al. Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: prevention by the targeted antioxidant MitoQ. Free Radic Biol Med 2010, 49:748-756.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 748-756
-
-
Vergeade, A.1
Mulder, P.2
Vendeville-Dehaudt, C.3
Estour, F.4
Fortin, D.5
Ventura-Clapier, R.6
-
144
-
-
77955283395
-
Animal and human studies with the mitochondria-targeted antioxidant MitoQ
-
Smith R.A., Murphy M.P. Animal and human studies with the mitochondria-targeted antioxidant MitoQ. Ann N Y Acad Sci 2010, 1201:96-103.
-
(2010)
Ann N Y Acad Sci
, vol.1201
, pp. 96-103
-
-
Smith, R.A.1
Murphy, M.P.2
-
145
-
-
67649757115
-
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury
-
Prime T.A., Blaikie F.H., Evans C., Nadtochiy S.M., James A.M., Dahm C.C., et al. A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A 2009, 106:10764-10769.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 10764-10769
-
-
Prime, T.A.1
Blaikie, F.H.2
Evans, C.3
Nadtochiy, S.M.4
James, A.M.5
Dahm, C.C.6
-
146
-
-
0028134892
-
Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
-
Brown G.C., Cooper C.E. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 1994, 356:295-298.
-
(1994)
FEBS Lett
, vol.356
, pp. 295-298
-
-
Brown, G.C.1
Cooper, C.E.2
-
147
-
-
84856228755
-
Novel therapies targeting inner mitochondrial membrane - from discovery to clinical development
-
Szeto H.H., Schiller P.W. Novel therapies targeting inner mitochondrial membrane - from discovery to clinical development. Pharm Res 2011, 28:2669-2679.
-
(2011)
Pharm Res
, vol.28
, pp. 2669-2679
-
-
Szeto, H.H.1
Schiller, P.W.2
-
148
-
-
4544370680
-
Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
-
Zhao K., Zhao G.M., Wu D., Soong Y., Birk A.V., Schiller P.W., et al. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J Biol Chem 2004, 279:34682-34690.
-
(2004)
J Biol Chem
, vol.279
, pp. 34682-34690
-
-
Zhao, K.1
Zhao, G.M.2
Wu, D.3
Soong, Y.4
Birk, A.V.5
Schiller, P.W.6
-
149
-
-
84879481183
-
Mitochondrially targeted compounds and their impact on cellular bioenergetics
-
Reily C., Mitchell T., Chacko B.K., Benavides G., Murphy M.P., Darley-Usmar V. Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biol 2013, 1:86-93.
-
(2013)
Redox Biol
, vol.1
, pp. 86-93
-
-
Reily, C.1
Mitchell, T.2
Chacko, B.K.3
Benavides, G.4
Murphy, M.P.5
Darley-Usmar, V.6
-
150
-
-
84881090284
-
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin
-
Birk A.V., Liu S., Soong Y., Mills W., Singh P., Warren J.D., et al. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. J Am Soc Nephrol 2013, 24:1250-1261.
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1250-1261
-
-
Birk, A.V.1
Liu, S.2
Soong, Y.3
Mills, W.4
Singh, P.5
Warren, J.D.6
-
151
-
-
69449084720
-
Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure
-
Saini-Chohan H.K., Holmes M.G., Chicco A.J., Taylor W.A., Moore R.L., McCune S.A., et al. Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure. J Lipid Res 2009, 50:1600-1608.
-
(2009)
J Lipid Res
, vol.50
, pp. 1600-1608
-
-
Saini-Chohan, H.K.1
Holmes, M.G.2
Chicco, A.J.3
Taylor, W.A.4
Moore, R.L.5
McCune, S.A.6
-
152
-
-
84875149020
-
Reduction of ischemia/reperfusion injury with bendavia, a mitochondria-targeting cytoprotective Peptide
-
Kloner R.A., Hale S.L., Dai W., Gorman R.C., Shuto T., Koomalsingh K.J., et al. Reduction of ischemia/reperfusion injury with bendavia, a mitochondria-targeting cytoprotective Peptide. J Am Heart Assoc 2012, 1:e001644.
-
(2012)
J Am Heart Assoc
, vol.1
-
-
Kloner, R.A.1
Hale, S.L.2
Dai, W.3
Gorman, R.C.4
Shuto, T.5
Koomalsingh, K.J.6
-
153
-
-
84890911734
-
Reduction of early reperfusion injury with the mitochondria-targeting Peptide bendavia
-
Brown D.A., Hale S.L., Baines C.P., Rio C.L., Hamlin R.L., Yueyama Y., et al. Reduction of early reperfusion injury with the mitochondria-targeting Peptide bendavia. J Cardiovasc Pharmacol Ther 2013, 19:121-132.
-
(2013)
J Cardiovasc Pharmacol Ther
, vol.19
, pp. 121-132
-
-
Brown, D.A.1
Hale, S.L.2
Baines, C.P.3
Rio, C.L.4
Hamlin, R.L.5
Yueyama, Y.6
-
154
-
-
84875422028
-
Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction
-
[e7]
-
Chakrabarti A.K., Feeney K., Abueg C., Brown D.A., Czyz E., Tendera M., et al. Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction. Am Heart J 2013, 165:509-514. [e7].
-
(2013)
Am Heart J
, vol.165
, pp. 509-514
-
-
Chakrabarti, A.K.1
Feeney, K.2
Abueg, C.3
Brown, D.A.4
Czyz, E.5
Tendera, M.6
|