Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex i

Nature Medicine

Volumn 19, Issue 6, 2013, Pages 753-759

  Chouchani, Edward T ^a,b   Methner, Carmen ^b   Nadtochiy, Sergiy M ^c   Logan, Angela ^a   Pell, Victoria R ^b   Ding, Shujing ^a   James, Andrew M ^a   Cochemé, Helena M ^a,d   Reinhold, Johannes ^a   Lilley, Kathryn S ^e   Partridge, Linda ^d   Fearnley, Ian M ^a   Robinson, Alan J ^a   Hartley, Richard C ^f   Smith, Robin A J ^g   Krieg, Thomas ^b   Brookes, Paul S ^c   Murphy, Michael P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

^g UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; INHIBITION KINETICS; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NITROSATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY; RESPIRATORY CHAIN; TISSUE NECROSIS;

ANIMALS; CYSTEINE; ELECTRON TRANSPORT COMPLEX I; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCARDIAL REPERFUSION INJURY; NITROSATION; PROTEIN SUBUNITS; RATS; REACTIVE OXYGEN SPECIES;

MUS;

EID: 84880253528     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3212     Document Type: Article

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