Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ

Free Radical Biology and Medicine

Volumn 49, Issue 5, 2010, Pages 748-756

  Vergeade, Aurélia ^a   Mulder, Paul ^a   Vendeville Dehaudt, Cathy ^a   Estour, François ^a   Fortin, Dominique ^b   Ventura Clapier, Renée ^b   Thuillez, Christian ^a   Monteil, Christelle ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b Universite Paris Sud   (France)

Author keywords

Cardiac dysfunction; Cocaine; Free radicals; Heart; Interfibrillar mitochondria; Mitochondria; MitoQ; Reactive oxygen species

Indexed keywords

10 (6' UBIQUINOLYL)DECYLTRIPHENYLPHOSPHONIUM; ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ANTIOXIDANT; CITRATE SYNTHASE; COCAINE; CREATINE KINASE; MITOQ; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; HEART DISEASE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART PROTECTION; HEMODYNAMIC PARAMETERS; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

RATTUS;

EID: 77955095876     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.05.024     Document Type: Article

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