Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation

eLife

Volumn 2014, Issue 3, 2014, Pages

  Phee, Hyewon ^a   Au Yeung, Byron B ^b   Pryshchep, Olga ^a   O'Hagan, Kyle Leonard ^a   Fairbairn, Stephanie Grace ^a   Radu, Maria ^c   Kosoff, Rachelle ^c   Mollenauer, Marianne ^b   Cheng, Debra ^b   Chernoff, Jonathan ^c   Weiss, Arthur ^b,d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA7 INTEGRIN; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD24 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; F ACTIN; HERMES ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 7 RECEPTOR ALPHA; KRUPPEL LIKE FACTOR 2; L SELECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR RECEPTOR NUR77; PROTEIN S6; RAC1 PROTEIN; SPHINGOSINE 1 PHOSPHATE RECEPTOR; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR; P21 ACTIVATED KINASE; PAK2 PROTEIN, MOUSE;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW; C57BL 6 MOUSE; CELL DEATH; CELL MATURATION; CELL SPREADING; CHIMERA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; FLOW CYTOMETRY; GENE; GENOTYPE; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PAK2 GENE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THYMOCYTE; ANIMAL; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ACTIN CYTOSKELETON; ANIMALS; MICE; MICE, KNOCKOUT; P21-ACTIVATED KINASES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; THYMOCYTES;

EID: 84900471535     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.02270     Document Type: Article

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