A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

EMBO Journal

Volumn 17, Issue 19, 1998, Pages 5647-5657

  Yablonski, Deborah ^a   Kane, Lawrence P ^a   Qian, Dapeng ^a,b   Weiss, Arthur ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SUGEN INC   (United States)

Author keywords

Nck; NFAT; Pak1; Signal transduction; TCR

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTO ONCOGENE; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MITOGEN-ACTIVATED PROTEIN KINASES; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0032188987     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.19.5647     Document Type: Article

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