Phosphorylation of p85 βPIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth

Journal of Biological Chemistry

Volumn 277, Issue 46, 2002, Pages 44417-44430

  Shin, Eun Young ^a   Shin, Kyung Sun ^b   Lee, Chan Soo ^a   Woo, Kyung Nam ^a   Quan, Song Hua ^a   Soung, Nak Kyun ^a   Kim, Young Gyu ^a   Cha, Choong Ik ^c   Kim, Seung Ryul ^a   Park, Dongeun ^d   Bokoch, Gary M ^e   Kim, Eung Gook ^a  

^a Chungbuk National University College of Medicine   (South Korea)

^b Daewoong Pharmaceutical Co Ltd   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Seoul National University   (South Korea)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ELECTROPHORESIS; MUTAGENESIS;

PHOSPHORYLATION;

GROWTH KINETICS;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALANINE; BASIC FIBROBLAST GROWTH FACTOR; BETA PAK INTERACTING FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GROWTH FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; P2 ACTIVATED KINASE; PAK INTERACTING FACTOR; PROTEIN CDC42; PROTEIN KINASE; PROTEIN P21; PROTEIN P85; RAC PROTEIN; RAS PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; GROWTH CONE; LAMELLIPODIUM; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; FIBROBLAST GROWTH FACTOR 2; GUANINE NUCLEOTIDE EXCHANGE FACTORS; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NEURONS; PC12 CELLS; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN TRANSPORT; RATS; SERINE; SIGNAL TRANSDUCTION; TETRACYCLINE; THREONINE; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0347155585     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203754200     Document Type: Article

References (71)

1. Zheng, Y. (2001) Trends Biochem. Sci. 26, 724-732
2. Hall, A. (1998) Science 279, 509-514
3. Mackay, D. J., Nobes, C. D., and Hall, A. (1995) Trends Neurosci. 18, 496-501
4. Albertinazzi, C., Gilardelli, D., Paris, S., Longhi, R., and de Curtis, I. (1998) J. Cell Biol. 142, 815-825
5. Brouns, M. R., Matheson, S. F., and Settleman, J. (2001) Nat. Cell Biol. 3, 361-367
6. Lehmann, M., Fournier, A., Selles-Navarro, I., Dergham, P., Sebok, A., Leclerc, N., Tigyi, G., and McKerracher, L. (1999) J. Neurosci. 19, 7537-7547
7. Tanabe, K., Tachibana, T., Yamashita, T., Che, Y. H., Yoneda, Y., Ochi, T., Tohyama, M., Yoshikawa, H., and Kiyama, H. (2000) J. Neurosci. 20, 4138-4144
8. Luo, L., Liao, Y. J., Jan, L. Y., and Jan, Y. N. (1994) Genes Dev. 8, 1787-1802
9. Lamoureux, P., Altun-Gultekin, Z. F., Lin, C., Wagner, J. A., and Heidemann, S. R. (1997) J. Cell Sci. 110, 635-641
10. Kuhn, T. B., Brown, M. D., and Bamburg, J. R. (1998) J. Neurobiol. 37, 524-540
11. Luo, L. (2000) Nat. Rev. Neurosci. 1, 173-180
12. Kim, M. D., Kolodziej, P., and Chiba, A. (2002) J. Neurosci. 22, 1794-1806
13. Jalink, K., van Corven, E. J., Hengeveld, T., Morii, N., Narumiya, S., and Moolenaar, W. H. (1994) J. Cell Biol. 126, 801-810
14. Kranenburg, O., Poland, M., van Horck, F. P., Drechsel, D., Hall, A., and Moolenaar, W. H. (1999) Mol. Biol. Cell 10, 1851-1857
15. Shamah, S. M., Lin, M. Z., Goldberg, J. L., Estrach, S., Sahin, M., Hu, L., Bazalakova, M., Neve, R. L., Corfas, G., Debant, A., and Greenberg, M. E. (2001) Cell 105, 233-244
16. Altun-Gultekin, Z. F., and Wagner, J. A. (1996) J. Neurosci. Res. 44, 308-327
17. Chen, X. Q., Tan, I., Leung, T., and Lim, L. (1999) J. Biol. Chem. 274, 19901-19905
18. Kita, Y., Kimura, K. D., Kobayashi, M., Ihara, S., Kaibuchi, K., Kuroda, S., Ui, M., Iba, H., Konishi, H., Kikkawa, U., Nagata, S., and Fukui, Y. (1998) J. Cell Sci. 111, 907-915
19. Goi, T., Rusanescu, G., Urano, T., and Feig, L. A. (1999) Mol. Cell. Biol. 19, 1731-1741
20. Posern, G., Saffrich, R., Ansorge, W., and Feller, S. M. (2000) J. Cell. Physiol. 183, 416-424
21. Manser, E., Loo, T. H., Koh, C. G., Zhao, Z. S., Chen, X. Q., Tan, L., Tan, I., Leung, T., and Lim, L. (1998) Mol. Cell 1, 183-192
22. Dan, I., Watanabe, N. M., and Kusumi, A. (2001) Trends Cell Biol. 11, 220-230
23. Manser, E., Leung, T., Salihuddin, H., Zhao, Z. S., and Lim, L. (1994) Nature 367, 40-46
24. Dan, C., Nath, N., Liberto, M., and Minden, A. (2002) Mol. Cell. Biol. 22, 567-577
25. Obermeier, A., Ahmed, S., Manser, E., Yen, S. C., Hall, C., and Lim, L. (1998) EMBO J. 17, 4328-4339
26. Daniels, R. H., Hall, P. S., and Bokoch, G. M. (1998) EMBO J. 17, 754-764
27. Lehmann, J. M., Riethmuller, G., and Johnson, J. P. (1990) Nucleic Acids Res. 18, 1048
28. Bagrodia, S., Taylor, S. J., Creasy, C. L., Chernoff, J., and Cerione, R. A. (1995) J. Biol. Chem. 270, 22731-22737
29. Bokoch, G. M., Wang, Y., Bohl, B. P., Sells, M. A., Quilliam, L. A., and Knaus, U. G. (1996) J. Biol. Chem. 271, 25746-25749
30. Lu, W., Katz, S., Gupta, R., and Mayer, B. J. (1997) Curr. Biol. 7, 85-94
31. Sells, M. A., Knaus, U. G., Bagrodia, S., Ambrose, D. M., Bokoch, G. M., and Chernoff, J. (1997) Curr. Biol. 7, 202-210
32. Nishimura, R., Li, W., Kashishian, A., Mondino, A., Zhou, M., Cooper, J., and Schlessinger, J. (1993) Mol. Cell. Biol. 13, 6889-6896
33. Park, D., and Rhee, S. G. (1992) Mol. Cell. Biol. 12, 5816 -5823
34. Meisenhelder, J., and Hunter, T. (1992) Mol. Cell. Biol. 12, 5843-5856
35. Tang, J., Feng, G. S., and Li, W. (1997) Oncogene 15, 1823-1832
36. Galisteo, M. L., Chernoff, J., Su, Y. C., Skolnik, E. Y., and Schlessinger, J. (1996) J. Biol. Chem. 271, 20997-21000
37. Rockow, S., Tang, J., Xiong, W., and Li, W. (1996) Oncogene 12, 2351-2359
38. Oh, W. K., Yoo, J. C., Jo, D., Song, Y. H., Kim, M. G., and Park, D. (1997) Biochem. Biophys. Res. Commun. 235, 794-798
39. Koh, C. G., Manser, E., Zhao, Z. S., Ng, C. P., and Lim, L. (2001) J. Cell Sci. 114, 4239-4251
40. Kim, S., Kim, T., Lee, D., Park, S. H., Kim, H., and Park, D. (2000) Biochem. Biophys. Res. Commun. 272, 721-725
41. Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., and Cerione, R. A. (1998) J. Biol. Chem. 273, 23633-23636
42. Feng, Q., Albeck, J. G., Cerione, R. A., and Yang, W. (2002) J. Biol. Chem. 277, 5644-5650
43. Bagrodia, S., Bailey, D., Lenard, Z., Hart, M., Guan, J. L., Premont, R. T., Taylor, S. J., and Cerione, R. A. (1999) J. Biol. Chem. 274, 22393-22400
44. Turner, C. E., Brown, M. C., Perrotta, J. A., Riedy, M. C., Nikolopoulos, S. N., McDonald, A. R., Bagrodia, S., Thomas, S., and Leventhal, P. S. (1999) J. Cell Biol. 145, 851-863
45. Zhao, Z. S., Manser, E., Loo, T. H., and Lim, L. (2000) Mol. Cell, Biol. 20, 6354-6363
46. Kim, S., Lee, S. H., and Park, D. (2001) J. Biol. Chem. 276, 10581-10584
47. Yoshii, S., Tanaka, M., Otsuki, Y., Wang, D. Y., Guo, R. J., Zhu, Y., Takeda, R., Hanai, H., Kaneko, E., and Sugimura, H. (1999) Oncogene 18, 5680-5690
48. Kim, E. G., Kwon, H. M., Burrow, C. R., and Ballermann, B. J. (1993) Am. J. Physiol. 264, F66-F73
49. Bustelo, X. R. (2000) Mol. Cell. Biol. 20, 1461-1477
50. Fleming, I. N., Elliott, C. M., Collard, J. G., and Exton, J. H. (1997) J. Biol. Chem. 272, 33105-33110
51. Zhao, Z. S., Manser, E., Chen, X. Q., Chong, C., Leung, T., and Lim, L. (1998) Mol. Cell. Biol. 18, 2153-2163
52. Daniels, R. H., Zenke, F. T., and Bokoch, G. M. (1999) J. Biol. Chem. 274, 6047-6050
53. Cowley, S., Paterson, H., Kemp, P., and Marshall, C. J. (1994) Cell 77, 841-852
54. Pang, L., Sawada, T., Decker, S. J., and Saltiel, A. R. (1995) J. Biol. Chem. 270, 13585-13588
55. Hadari, Y. R., Kouhara, H., Lax, I., and Schlessinger, J. (1998) Mol. Cell. Biol. 18, 3966-3973
56. Meakin, S. O., and MacDonald, J. I. (1998) J. Neurochem. 71, 1875-1888
57. Grewal, S. S., York, R. D., and Stork, P. J. (1999) Curr. Opin. Neurobiol. 9, 544-553
58. Robinson, M. J., Stippec, S. A., Goldsmith, E., White, M. A., and Cobb, M. H. (1998) Curr. Biol. 8, 1141-1150
59. Rudel, T., and Bokoch, G. M. (1997) Science 276, 1571-1574
60. Nunn, M. F., and Marsh, J. W. (1996) J. Virol. 70, 6157-6161
61. Renkema, G. H., Manninen, A., Mann, D. A., Harris, M., and Saksela, K. (1999) Curr. Biol. 9, 1407-1410
62. Roig, J., Tuazon, P. T., Zipfel, P. A., Pendergast, A. M., and Traugh, J. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 14346-14351
63. Chong, C., Tan, L., Lim, L., and Manser, E. (2001) J. Biol. Chem. 276, 17347-17353
64. Bokoch, G. M., Reilly, A. M., Daniels, R. H., King, C. C., Olivera, A., Spiegel, S., and Knaus, U. G. (1998) J. Biol. Chem. 273, 8137-8144
65. King, C. C., Gardiner, E. M., Zenke, F. T., Bohl, B. P., Newton, A. C., Hemmings, B. A., and Bokoch, G. M. (2000) J. Biol. Chem. 275, 41201-41209
66. Aghazadeh, B., Zhu, K., Kubiseski, T. J., Liu, G. A., Pawson, T., Zheng, Y., and Rosen, M. K. (1998) Nat. Struct. Biol. 5, 1098-1107
67. Han, J., Luby-Phelps, K., Das, B., Shu, X., Xia, Y., Mosteller, R. D., Krishna, U. M., Falck, J. R., White, M. A., and Broek, D. (1998) Science 279, 558-560
68. Di Cesare, A., Paris, S., Albertinazzi, C., Dariozzi, S., Andersen, J., Mann, M., Longhi, R., and de Curtis, I. (2000) Nat. Cell Biol. 2, 521-530
69. Brown, M. C., Perrotta, J. A., and Turner, C. E. (1998) Mol. Biol. Cell 9, 1803-1816
70. Petit, V., Boyer, B., Lentz, D., Turner, C. E., Thiery, J. P., and Valles, A. M. (2000) J. Cell Biol. 148, 957-970
71. Matafora, V., Paris, S., Dariozzi, S., and de Curtis, I. (2001) J. Cell Sci. 114, 4509-4520