메뉴 건너뛰기




Volumn 113, Issue 17, 2009, Pages 3990-3998

Rac GTPases play critical roles in early T-cell development

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; NOTCH RECEPTOR; RAC GUANOSINE TRIPHOSPHATASE; RAC PROTEIN; RAC1 PROTEIN; RAC2 PROTEIN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG; VAV PROTEIN; VAV1 PROTEIN; VAV2 PROTEIN; INTERLEUKIN 7; LYMPHOCYTE ANTIGEN RECEPTOR; NEUROPEPTIDE; RAC1 PROTEIN, MOUSE;

EID: 65449180370     PISSN: 00064971     EISSN: 15280020     Source Type: None    
DOI: 10.1182/blood-2008-09-181180     Document Type: Article
Times cited : (61)

References (48)
  • 1
    • 38449106709 scopus 로고    scopus 로고
    • The thymus as an inductive site for T lymphopoiesis
    • Ciofani M, Zuniga-Pflucker JC. The thymus as an inductive site for T lymphopoiesis. Annu Rev Cell Dev Biol. 2007;23:463-493.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 463-493
    • Ciofani, M.1    Zuniga-Pflucker, J.C.2
  • 2
    • 18844449626 scopus 로고    scopus 로고
    • Vav-family proteins in T-cell signalling
    • Tybulewicz VLJ. Vav-family proteins in T-cell signalling. Curr Opin Immunol. 2005;17:267-274.
    • (2005) Curr Opin Immunol , vol.17 , pp. 267-274
    • Tybulewicz, V.L.J.1
  • 5
    • 33748994545 scopus 로고    scopus 로고
    • Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
    • Ridley AJ. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol. 2006;16:522-529.
    • (2006) Trends Cell Biol , vol.16 , pp. 522-529
    • Ridley, A.J.1
  • 6
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol. 2005;21:247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 7
    • 0142116231 scopus 로고    scopus 로고
    • Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling
    • Walmsley MJ, Ooi SK, Reynolds LF, et al. Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. Science. 2003;302:459-462.
    • (2003) Science , vol.302 , pp. 459-462
    • Walmsley, M.J.1    Ooi, S.K.2    Reynolds, L.F.3
  • 8
    • 0034305495 scopus 로고    scopus 로고
    • Control of pre-T cell proliferation and differentiation by the GTPase Rac-1
    • Gomez M, Tybulewicz V, Cantrell DA. Control of pre-T cell proliferation and differentiation by the GTPase Rac-1. Nat Immunol. 2000;1:348-352.
    • (2000) Nat Immunol , vol.1 , pp. 348-352
    • Gomez, M.1    Tybulewicz, V.2    Cantrell, D.A.3
  • 9
    • 0035652283 scopus 로고    scopus 로고
    • The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection
    • DOI 10.1016/S1074-7613(01)00235-7
    • Gomez M, Kioussis D, Cantrell DA. The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection. Immunity. 2001;15:703-713. (Pubitemid 34008499)
    • (2001) Immunity , vol.15 , Issue.5 , pp. 703-713
    • Gomez, M.1    Kioussis, D.2    Cantrell, D.A.3
  • 10
    • 0030772153 scopus 로고    scopus 로고
    • Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase
    • Lorès P, Morin L, Luna R, Gacon G. Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase. Oncogene. 1997;15:601-605. (Pubitemid 27384738)
    • (1997) Oncogene , vol.15 , Issue.5 , pp. 601-605
    • Lores, P.1    Morin, L.2    Luna, R.3    Gacon, G.4
  • 12
    • 0035477599 scopus 로고    scopus 로고
    • Deficiency of small GTPase Rac2 affects T cell activation
    • DOI 10.1084/jem.194.7.915
    • Yu H, Leitenberg D, Li B, Flavell RA. Deficiency of small GTPase Rac2 affects T cell activation. J Exp Med. 2001;194:915-926. (Pubitemid 32953261)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.7 , pp. 915-925
    • Yu, H.1    Leitenberg, D.2    Li, B.3    Flavell, R.A.4
  • 16
    • 0038445857 scopus 로고    scopus 로고
    • DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-θ and LFA-1, in T cells
    • DOI 10.1016/S1074-7613(03)00169-9
    • Sanui T, Inayoshi A, Noda M, et al. DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells. Immunity. 2003;19:119-129. (Pubitemid 36859906)
    • (2003) Immunity , vol.19 , Issue.1 , pp. 119-129
    • Sanui, T.1    Inayoshi, A.2    Noda, M.3    Iwata, E.4    Oike, M.5    Sasazuki, T.6    Fukui, Y.7
  • 18
    • 34547654200 scopus 로고    scopus 로고
    • SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling
    • Bé cart S, Charvet C, Canonigo Balancio AJ, et al. SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling. J Clin Invest. 2007;117:2164-2175.
    • (2007) J Clin Invest , vol.117 , pp. 2164-2175
    • Bécart, S.1    Charvet, C.2    Canonigo Balancio, A.J.3
  • 21
    • 0027711831 scopus 로고
    • Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen
    • Mamalaki C, Elliot J, Norton T, et al. Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen. Dev Immunol. 1993;3:159-174.
    • (1993) Dev Immunol , vol.3 , pp. 159-174
    • Mamalaki, C.1    Elliot, J.2    Norton, T.3
  • 23
    • 27144463982 scopus 로고    scopus 로고
    • Vav proteins regulate peripheral B-cell survival
    • DOI 10.1182/blood-2004-12-4894
    • Vigorito E, Gambardella L, Colucci F, McAdam S, Turner M. Vav proteins regulate peripheral B-cell survival. Blood. 2005;106:2391-2398. (Pubitemid 41510812)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2391-2398
    • Vigorito, E.1    Gambardella, L.2    Colucci, F.3    McAdam, S.4    Turner, M.5
  • 25
    • 33645099763 scopus 로고    scopus 로고
    • Thymic microenvironments for T cell differentiation and selection
    • Ladi E, Yin X, Chtanova T, Robey EA. Thymic microenvironments for T cell differentiation and selection. Nat Immunol. 2006;7:338-343.
    • (2006) Nat Immunol , vol.7 , pp. 338-343
    • Ladi, E.1    Yin, X.2    Chtanova, T.3    Robey, E.A.4
  • 26
    • 0035179974 scopus 로고    scopus 로고
    • - (DN4) subset
    • DOI 10.1002/1521-4141(200111)31:11<3308::AID-IMMU3308>3.0.CO;2-5
    • Falk I, Nerz G, Haidl I, Krotkova A, Eichmann K. Immature thymocytes that fail to express TCRbeta and/or TCRgamma delta proteins die by apoptotic cell death in the CD44(-)CD25(-) (DN4) subset. Eur J Immunol. 2001;31:3308-3317. (Pubitemid 33100523)
    • (2001) European Journal of Immunology , vol.31 , Issue.11 , pp. 3308-3317
    • Falk, I.1    Nerz, G.2    Haidl, I.3    Krotkova, A.4    Eichmann, K.5
  • 27
    • 4143151485 scopus 로고    scopus 로고
    • IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: Impact on thymocyte development
    • DOI 10.1084/jem.20032183
    • Yu Q, Erman B, Park JH, Feigenbaum L, Singer A. IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development. J Exp Med. 2004;200:797-803. (Pubitemid 39299465)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.6 , pp. 797-803
    • Yu, Q.1    Erman, B.2    Park, J.-H.3    Feigenbaum, L.4    Singer, A.5
  • 28
    • 0030874326 scopus 로고    scopus 로고
    • The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression
    • DOI 10.1016/S1074-7613(00)80517-8
    • von Freeden-Jeffry U, Solvason N, Howard M, Murray R. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity. 1997;7:147-154. (Pubitemid 27357272)
    • (1997) Immunity , vol.7 , Issue.1 , pp. 147-154
    • Von Freeden-Jeffry, U.1    Solvason, N.2    Howard, M.3    Murray, R.4
  • 29
    • 1542317449 scopus 로고    scopus 로고
    • Notch regulation of lymphocyte development and function
    • DOI 10.1038/ni1045
    • Radtke F, Wilson A, Mancini SJ, MacDonald HR. Notch regulation of lymphocyte development and function. Nat Immunol. 2004;5:247-253. (Pubitemid 38332121)
    • (2004) Nature Immunology , vol.5 , Issue.3 , pp. 247-253
    • Radtke, F.1    Wilson, A.2    Mancini, S.J.C.3    MacDonald, H.R.4
  • 30
    • 0030840415 scopus 로고    scopus 로고
    • Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor
    • Luo B, Aster JC, Hasserjian RP, Kuo F, Sklar J. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol Cell Biol. 1997;17:6057-6067. (Pubitemid 27411114)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.10 , pp. 6057-6067
    • Luo, B.1    Aster, J.C.2    Hasserjian, R.P.3    Kuo, F.4    Sklar, J.5
  • 31
    • 33748507998 scopus 로고    scopus 로고
    • Notch1 and IL-7 receptor interplay maintains proliferation of human thymic progenitors while suppressing non-T cell fates
    • García-Peydró M, de Yebenes VG, Toribio ML. Notch1 and IL-7 receptor interplay maintains proliferation of human thymic progenitors while suppressing non-T cell fates. J Immunol. 2006;177:3711-3720. (Pubitemid 44359903)
    • (2006) Journal of Immunology , vol.177 , Issue.6 , pp. 3711-3720
    • Garcia-Peydro, M.1    De Yebenes, V.G.2    Toribio, M.L.3
  • 34
    • 0032981244 scopus 로고    scopus 로고
    • The Rho-family GTP exchange factor Vav is a critical transducer of TCR signals to the calcium, ERK and NF-kB pathways
    • Costello PS, Walters AE, Mee PJ, et al. The Rho-family GTP exchange factor Vav is a critical transducer of TCR signals to the calcium, ERK and NF-kB pathways. Proc Natl Acad Sci U S A. 1999;96:3035-3040.
    • (1999) Proc Natl Acad Sci U S a , vol.96 , pp. 3035-3040
    • Costello, P.S.1    Walters, A.E.2    Mee, P.J.3
  • 39
    • 0034695453 scopus 로고    scopus 로고
    • A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation
    • DOI 10.1074/jbc.275.3.2185
    • Kuhne MR, Ku G, Weiss A. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation. J Biol Chem. 2000;275:2185-2190. (Pubitemid 30060848)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.3 , pp. 2185-2190
    • Kuhne, M.R.1    Ku, G.2    Weiss, A.3
  • 41
    • 52649136968 scopus 로고    scopus 로고
    • Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development
    • Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y. Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood. 2008;112:1767-1775.
    • (2008) Blood , vol.112 , pp. 1767-1775
    • Guo, F.1    Cancelas, J.A.2    Hildeman, D.3    Williams, D.A.4    Zheng, Y.5
  • 43
    • 2442522357 scopus 로고    scopus 로고
    • Regulation of αβ/γδ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
    • Tanigaki K, Tsuji M, Yamamoto N, et al. Regulation of αβ/γδ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity. 2004;20:611-622.
    • (2004) Immunity , vol.20 , pp. 611-622
    • Tanigaki, K.1    Tsuji, M.2    Yamamoto, N.3
  • 44
    • 0036070308 scopus 로고    scopus 로고
    • Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ lineage thymocytes
    • DOI 10.1016/S1074-7613(02)00330-8
    • Wolfer A, Wilson A, Nemir M, MacDonald HR, Radtke F. Inactivation of Notch1 impairs VDJβ rearrangement and allows pre-TCR-independent survival of early αβ lineage. Immunity. 2002;16:869-879. (Pubitemid 34786485)
    • (2002) Immunity , vol.16 , Issue.6 , pp. 869-879
    • Wolfer, A.1    Wilson, A.2    Nemir, M.3    MacDonald, H.R.4    Radtke, F.5
  • 45
    • 0041428109 scopus 로고    scopus 로고
    • Surface expression of Notch1 on thymocytes: Correlation with the double-negative to double-positive transition
    • Huang EY, Gallegos AM, Richards SM, Lehar SM, Bevan MJ. Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition. J Immunol. 2003;171:2296-2304.
    • (2003) J Immunol , vol.171 , pp. 2296-2304
    • Huang, E.Y.1    Gallegos, A.M.2    Richards, S.M.3    Lehar, S.M.4    Bevan, M.J.5
  • 46
    • 26644459229 scopus 로고    scopus 로고
    • The role of Erk1 and Erk2 in multiple stages of T cell development
    • DOI 10.1016/j.immuni.2005.08.013, PII S1074761305003043
    • Fischer AM, Katayama CD, Pages G, Pouyssegur J, Hedrick SM. The Role of Erk1 and Erk2 in multiple stages of T cell development. Immunity. 2005;23:431-443. (Pubitemid 41443444)
    • (2005) Immunity , vol.23 , Issue.4 , pp. 431-443
    • Fischer, A.M.1    Katayama, C.D.2    Pages, G.3    Pouyssegur, J.4    Hedrick, S.M.5
  • 47
    • 0033653934 scopus 로고    scopus 로고
    • Multiple roles of the Dcdc42 GTPase during wing development in Drosophila melanogaster
    • Baron M, O'Leary V, Evans DA, Hicks M, Hudson K. Multiple roles of the Dcdc42 GTPase during wing development in Drosophila melanogaster. Mol Gen Genet. 2000;264:98-104.
    • (2000) Mol Gen Genet , vol.264 , pp. 98-104
    • Baron, M.1    O'Leary, V.2    Evans, D.A.3    Hicks, M.4    Hudson, K.5
  • 48
    • 28144458897 scopus 로고    scopus 로고
    • Developmental biology: LIN-12/notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans
    • DOI 10.1126/science.1119481
    • Yoo AS, Greenwald I. LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans. Science. 2005;310:1330-1333. (Pubitemid 41698865)
    • (2005) Science , vol.310 , Issue.5752 , pp. 1330-1333
    • Yoo, A.S.1    Greenwald, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.