-
1
-
-
34249284512
-
mTOR at the crossroads of T cell proliferation and tolerance
-
Mondino A, Mueller DL. mTOR at the crossroads of T cell proliferation and tolerance. Semin Immunol 2007; 19:162-72.
-
(2007)
Semin Immunol
, vol.19
, pp. 162-172
-
-
Mondino, A.1
Mueller, D.L.2
-
2
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006; 124:471-84.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
3
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, et al. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 2006; 127:125-37.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
-
4
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002; 110:163-75.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
-
5
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 2004; 18:1926-45.
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
6
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, Hall A, et al. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 2004; 6:1122-8.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
-
7
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, et al. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 2004; 14:1296-302.
-
(2004)
Curr Biol
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
-
8
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov DD, Ali SM, Sengupta S, Sheen JH, Hsu PP, Bagley AF, et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006; 22:159-68.
-
(2006)
Mol Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
-
9
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005; 307:1098-101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
10
-
-
52949137425
-
Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: Rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1
-
Rosner M, Hengstschlager M. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. Hum Mol Genet 2008; 17:2934-48.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2934-2948
-
-
Rosner, M.1
Hengstschlager, M.2
-
11
-
-
56149102256
-
Defects in skin gammadelta T cell function contribute to delayed wound repair in rapamycin-treated mice
-
Mills RE, Taylor KR, Podshivalova K, McKay DB, Jameson JM. Defects in skin gammadelta T cell function contribute to delayed wound repair in rapamycin-treated mice. J Immunol 2008; 181:3974-83.
-
(2008)
J Immunol
, vol.181
, pp. 3974-3983
-
-
Mills, R.E.1
Taylor, K.R.2
Podshivalova, K.3
McKay, D.B.4
Jameson, J.M.5
-
18
-
-
1542514772
-
A keratinocyte-responsive gammadelta TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis
-
Jameson JM, Cauvi G, Witherden DA, Havran WL. A keratinocyte-responsive gammadelta TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis. J Immunol 2004; 172:3573-9.
-
(2004)
J Immunol
, vol.172
, pp. 3573-3579
-
-
Jameson, J.M.1
Cauvi, G.2
Witherden, D.A.3
Havran, W.L.4
-
19
-
-
0025836121
-
Recognition of self antigens by skin-derived T cells with invariant gammadelta antigen receptors
-
Havran WL, Chien YH, Allison JP. Recognition of self antigens by skin-derived T cells with invariant gammadelta antigen receptors. Science 1991; 252:1430-2.
-
(1991)
Science
, vol.252
, pp. 1430-1432
-
-
Havran, W.L.1
Chien, Y.H.2
Allison, J.P.3
-
20
-
-
0035914134
-
Regulation of cutaneous malignancy by gammadelta T cells
-
Girardi M, Oppenheim DE, Steele CR, Lewis JM, Glusac E, Filler R, et al. Regulation of cutaneous malignancy by gammadelta T cells. Science 2001; 294:605-9.
-
(2001)
Science
, vol.294
, pp. 605-609
-
-
Girardi, M.1
Oppenheim, D.E.2
Steele, C.R.3
Lewis, J.M.4
Glusac, E.5
Filler, R.6
-
21
-
-
0037177385
-
A role for skin gammadelta T cells in wound repair
-
Jameson J, Ugarte K, Chen N, Yachi P, Fuchs E, Boismenu R, et al. A role for skin gammadelta T cells in wound repair. Science 2002; 296:747-9.
-
(2002)
Science
, vol.296
, pp. 747-749
-
-
Jameson, J.1
Ugarte, K.2
Chen, N.3
Yachi, P.4
Fuchs, E.5
Boismenu, R.6
-
22
-
-
18244374740
-
Gammadelta T cell-induced hyaluronan production by epithelial cells regulates inflammation
-
Jameson JM, Cauvi G, Sharp LL, Witherden DA, Havran WL. Gammadelta T cell-induced hyaluronan production by epithelial cells regulates inflammation. J Exp Med 2005; 201:1269-79.
-
(2005)
J Exp Med
, vol.201
, pp. 1269-1279
-
-
Jameson, J.M.1
Cauvi, G.2
Sharp, L.L.3
Witherden, D.A.4
Havran, W.L.5
-
23
-
-
12344306333
-
Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1
-
Sharp LL, Jameson JM, Cauvi G, Havran WL. Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1. Nat Immunol 2005; 6:73-9.
-
(2005)
Nat Immunol
, vol.6
, pp. 73-79
-
-
Sharp, L.L.1
Jameson, J.M.2
Cauvi, G.3
Havran, W.L.4
-
24
-
-
13244278180
-
The Pim kinases control rapamycin-resistant T cell survival and activation
-
Fox CJ, Hammerman PS, Thompson CB. The Pim kinases control rapamycin-resistant T cell survival and activation. J Exp Med 2005; 201:259-66.
-
(2005)
J Exp Med
, vol.201
, pp. 259-266
-
-
Fox, C.J.1
Hammerman, P.S.2
Thompson, C.B.3
-
25
-
-
44449100271
-
Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin
-
Basu S, Golovina T, Mikheeva T, June CH, Riley JL. Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. J Immunol 2008; 180:5794-8.
-
(2008)
J Immunol
, vol.180
, pp. 5794-5798
-
-
Basu, S.1
Golovina, T.2
Mikheeva, T.3
June, C.H.4
Riley, J.L.5
-
26
-
-
34548151890
-
P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration
-
Hernandez-Negrete I, Carretero-Ortega J, Rosenfeldt H, Hernandez-Garcia R, CalderonSalinas JV, Reyes-Cruz G, et al. P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration. J Biol Chem 2007; 282:23708-15.
-
(2007)
J Biol Chem
, vol.282
, pp. 23708-23715
-
-
Hernandez-Negrete, I.1
Carretero-Ortega, J.2
Rosenfeldt, H.3
Hernandez-Garcia, R.4
CalderonSalinas, J.V.5
Reyes-Cruz, G.6
-
27
-
-
46749115220
-
CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1
-
Murooka TT, Rahbar R, Platanias LC, Fish EN. CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1. Blood 2008; 111:4892-901.
-
(2008)
Blood
, vol.111
, pp. 4892-4901
-
-
Murooka, T.T.1
Rahbar, R.2
Platanias, L.C.3
Fish, E.N.4
-
28
-
-
42449110816
-
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
-
Sinclair LV, Finlay D, Feijoo C, Cornish GH, Gray A, Ager A, et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol 2008; 9:513-21.
-
(2008)
Nat Immunol
, vol.9
, pp. 513-521
-
-
Sinclair, L.V.1
Finlay, D.2
Feijoo, C.3
Cornish, G.H.4
Gray, A.5
Ager, A.6
-
29
-
-
23944437624
-
Chemokine control of lymphocyte trafficking: A general overview
-
Stein JV, Nombela-Arrieta C. Chemokine control of lymphocyte trafficking: a general overview. Immunology 2005; 116:1-12.
-
(2005)
Immunology
, vol.116
, pp. 1-12
-
-
Stein, J.V.1
Nombela-Arrieta, C.2
|