메뉴 건너뛰기




Volumn 35, Issue 4, 2014, Pages 2857-2869

The microRNA networks of TGFβ signaling in cancer

Author keywords

Angiogenesis; Cancer; Epithelial to mesenchymal transition; Metastases; MicroRNA; TGF SMAD signaling

Indexed keywords

MICRORNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84898784102     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1481-9     Document Type: Review
Times cited : (19)

References (150)
  • 1
    • 33750069029 scopus 로고    scopus 로고
    • Escaping from the TGFbeta anti-proliferative control
    • Seoane J. Escaping from the TGFbeta anti-proliferative control. Carcinogenesis. 2005;27(11):2148-56.
    • (2005) Carcinogenesis , vol.27 , Issue.11 , pp. 2148-2156
    • Seoane, J.1
  • 2
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in cancer
    • 3512574 18662538
    • Massagué J. TGFbeta in cancer. Cell. 2008;134:215-30.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massagué, J.1
  • 3
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • 11586292
    • Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet. 2001;29:117-29.
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 4
    • 27644494876 scopus 로고    scopus 로고
    • Smad transcription factors
    • 16322555
    • Massague J, Seoane J, Wotton D. Smad transcription factors. Genes Dev. 2005;19:2783-810.
    • (2005) Genes Dev , vol.19 , pp. 2783-2810
    • Massague, J.1    Seoane, J.2    Wotton, D.3
  • 5
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in tgf-beta signaling through Smads
    • 16212511
    • Feng XH, Derynck R. Specificity and versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev Biol. 2005;21:659-93.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 659-693
    • Feng, X.H.1    Derynck, R.2
  • 6
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • 12809600
    • Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003;113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 7
    • 0032763469 scopus 로고    scopus 로고
    • Specificity, diversity, and regulation in TGF-beta superfamily signaling
    • 10593858
    • Piek E, Heldin CH, Ten Dijke P. Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J. 1999;13:2105-24.
    • (1999) FASEB J , vol.13 , pp. 2105-2124
    • Piek, E.1    Heldin, C.H.2    Ten Dijke, P.3
  • 8
    • 58149269185 scopus 로고    scopus 로고
    • Endocytic regulation of TGF-beta signaling
    • 19050695
    • Chen YG. Endocytic regulation of TGF-beta signaling. Cell Res. 2009;19:58-70.
    • (2009) Cell Res , vol.19 , pp. 58-70
    • Chen, Y.G.1
  • 9
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-beta signaling
    • 2635127 19114990
    • Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009;19:128-39.
    • (2009) Cell Res , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 10
    • 36448936383 scopus 로고    scopus 로고
    • TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility
    • 18000526
    • Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol. 2007;8:970-82.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 11
    • 33747743119 scopus 로고    scopus 로고
    • The structural basis of TGF-beta, bone morphogenetic protein, and activin ligand binding
    • 16885528
    • Lin SJ, Lerch TF, Cook RW, Jardetzky TS, Woodruff TK. The structural basis of TGF-beta, bone morphogenetic protein, and activin ligand binding. Reproduction. 2006;132:179-90.
    • (2006) Reproduction , vol.132 , pp. 179-190
    • Lin, S.J.1    Lerch, T.F.2    Cook, R.W.3    Jardetzky, T.S.4    Woodruff, T.K.5
  • 12
    • 58149264873 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Smad proteins
    • 19114992
    • Hill CS. Nucleocytoplasmic shuttling of Smad proteins. Cell Res. 2009;19:36-46.
    • (2009) Cell Res , vol.19 , pp. 36-46
    • Hill, C.S.1
  • 13
    • 58149236744 scopus 로고    scopus 로고
    • Roles of TGFbeta in metastasis
    • 19050696
    • Padua D, Massague J. Roles of TGFbeta in metastasis. Cell Res. 2009;19(1):89-102.
    • (2009) Cell Res , vol.19 , Issue.1 , pp. 89-102
    • Padua, D.1    Massague, J.2
  • 14
    • 80155137594 scopus 로고    scopus 로고
    • Master transcription factors determine cell-type-specific responses to TGF-beta signaling
    • 3212730 22036565
    • Mullen AC, Orlando DA, Newman JJ, Loven J, Kumar RM, Bilodeau S, et al. Master transcription factors determine cell-type-specific responses to TGF-beta signaling. Cell. 2011;147:565-76.
    • (2011) Cell , vol.147 , pp. 565-576
    • Mullen, A.C.1    Orlando, D.A.2    Newman, J.J.3    Loven, J.4    Kumar, R.M.5    Bilodeau, S.6
  • 15
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • 15852042
    • Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol. 2005;6:376-85.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 16
    • 49849091679 scopus 로고    scopus 로고
    • Micromanagers of malignancy: Role of microRNAs in regulating metastasis
    • 18674843
    • Ma L, Weinberg RA. Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet. 2008;24:448-56.
    • (2008) Trends Genet , vol.24 , pp. 448-456
    • Ma, L.1    Weinberg, R.A.2
  • 17
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and microRNAs
    • 18369135
    • Hobert O. Gene regulation by transcription factors and microRNAs. Science. 2008;319:1785-6.
    • (2008) Science , vol.319 , pp. 1785-1786
    • Hobert, O.1
  • 18
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • 15211354
    • He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5:522-31.
    • (2004) Nat Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 19
    • 33645294070 scopus 로고    scopus 로고
    • OncomiRs-microRNAs with a role in cancer
    • 16557279
    • Esquela-Kerscher A, Slack FJ. OncomiRs-microRNAs with a role in cancer. Nat Rev Cancer. 2006;6:259-69.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 20
    • 0000201238 scopus 로고
    • Growth factors from murine sarcoma virus-transformed cells
    • 392918 211512
    • de Larco JE, Todaro GJ. Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci U S A. 1978;75:4001-5.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 4001-4005
    • De Larco, J.E.1    Todaro, G.J.2
  • 21
    • 0019303558 scopus 로고
    • Transforming growth factors: Isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction
    • 349643 6251462
    • Roberts AB, Lamb LC, Newton DL, Sporn MB, de Larco JE, Todaro GJ. Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction. Proc Natl Acad Sci U S A. 1980;77:3494-8.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 3494-3498
    • Roberts, A.B.1    Lamb, L.C.2    Newton, D.L.3    Sporn, M.B.4    De Larco, J.E.5    Todaro, G.J.6
  • 22
    • 4444338819 scopus 로고    scopus 로고
    • Molecular interactions that confer latency to transforming growth factor-beta
    • 15208302
    • Young GD, Murphy-Ullrich JE. Molecular interactions that confer latency to transforming growth factor-beta. J Biol Chem. 2004;279:38032-9.
    • (2004) J Biol Chem , vol.279 , pp. 38032-38039
    • Young, G.D.1    Murphy-Ullrich, J.E.2
  • 23
    • 0030058699 scopus 로고    scopus 로고
    • Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1
    • 449939 8617200
    • Saharinen J, Taipale J, Keski-Oja J. Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1. EMBO J. 1996;15:245-53.
    • (1996) EMBO J , vol.15 , pp. 245-253
    • Saharinen, J.1    Taipale, J.2    Keski-Oja, J.3
  • 25
    • 0030972496 scopus 로고    scopus 로고
    • Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues
    • 1169800 9155023
    • Luo K, Lodish HF. Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues. EMBO J. 1997;16:1970-81.
    • (1997) EMBO J , vol.16 , pp. 1970-1981
    • Luo, K.1    Lodish, H.F.2
  • 27
    • 58149239730 scopus 로고    scopus 로고
    • Phospho-control of TGF-beta superfamily signaling
    • 2929013 19114991
    • Wrighton KH, Lin X, Feng XH. Phospho-control of TGF-beta superfamily signaling. Cell Res. 2009;19:8-20.
    • (2009) Cell Res , vol.19 , pp. 8-20
    • Wrighton, K.H.1    Lin, X.2    Feng, X.H.3
  • 28
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • 11792802
    • Moustakas A, Souchelnytskyi S, Heldin CH. Smad regulation in TGF-beta signal transduction. J Cell Sci. 2001;114:4359-69.
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 29
    • 58149218252 scopus 로고    scopus 로고
    • Regulating the stability of TGFbeta receptors and Smads
    • 19030025
    • Lonn P, Moren A, Raja E, Dahl M, Moustakas A. Regulating the stability of TGFbeta receptors and Smads. Cell Res. 2009;19:21-35.
    • (2009) Cell Res , vol.19 , pp. 21-35
    • Lonn, P.1    Moren, A.2    Raja, E.3    Dahl, M.4    Moustakas, A.5
  • 30
    • 33846011104 scopus 로고    scopus 로고
    • Regulation of Smad activities
    • 1805629 17182123
    • Xu L. Regulation of Smad activities. Biochim Biophys Acta. 2006;1759:503-13.
    • (2006) Biochim Biophys Acta , vol.1759 , pp. 503-513
    • Xu, L.1
  • 32
    • 0141680424 scopus 로고    scopus 로고
    • Cell signaling and cancer
    • 14522250
    • Martin GS. Cell signaling and cancer. Cancer Cell. 2003;4:167-74.
    • (2003) Cancer Cell , vol.4 , pp. 167-174
    • Martin, G.S.1
  • 33
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-74.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 34
    • 0038274163 scopus 로고    scopus 로고
    • Links between tumor suppressors: P53 is required for TGF-beta gene responses by cooperating with Smads
    • 12732139
    • Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S. Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell. 2003;113:301-14.
    • (2003) Cell , vol.113 , pp. 301-314
    • Cordenonsi, M.1    Dupont, S.2    Maretto, S.3    Insinga, A.4    Imbriano, C.5    Piccolo, S.6
  • 35
    • 84886426165 scopus 로고    scopus 로고
    • Crosstalk between p53 and TGF-beta signalling
    • 3321553 22545213
    • Elston R, Inman GJ. Crosstalk between p53 and TGF-beta signalling. J Signal Transduct. 2012;2012:294097.
    • (2012) J Signal Transduct , vol.2012 , pp. 294097
    • Elston, R.1    Inman, G.J.2
  • 36
    • 63049136592 scopus 로고    scopus 로고
    • A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • 19345189
    • Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, et al. A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell. 2009;137:87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3    Dupont, S.4    Wong, C.5    Hann, B.6
  • 37
    • 65949113847 scopus 로고    scopus 로고
    • Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer
    • 2696277 19351843
    • Cohen J, Chen Z, Lu SL, Yang XP, Arun P, Ehsanian R, et al. Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. Cancer Res. 2009;69:3415-24.
    • (2009) Cancer Res , vol.69 , pp. 3415-3424
    • Cohen, J.1    Chen, Z.2    Lu, S.L.3    Yang, X.P.4    Arun, P.5    Ehsanian, R.6
  • 39
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
    • 316599 10197981
    • Kretzschmar M, Doody J, Timokhina I, Massague J. A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev. 1999;13:804-16.
    • (1999) Genes Dev , vol.13 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 41
    • 84868254278 scopus 로고    scopus 로고
    • MiRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma
    • 3488137 22964582
    • Kasinski AL, Slack FJ. miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res. 2012;72:5576-87.
    • (2012) Cancer Res , vol.72 , pp. 5576-5587
    • Kasinski, A.L.1    Slack, F.J.2
  • 43
    • 0037461931 scopus 로고    scopus 로고
    • Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter
    • 12545156
    • Wu S, Cetinkaya C, Munoz-Alonso MJ, der LN V, Bahram F, Beuger V, et al. Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. Oncogene. 2003;22:351-60.
    • (2003) Oncogene , vol.22 , pp. 351-360
    • Wu, S.1    Cetinkaya, C.2    Munoz-Alonso, M.J.3    Der Ln, V.4    Bahram, F.5    Beuger, V.6
  • 45
    • 57049085506 scopus 로고    scopus 로고
    • P53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
    • 2600669 19034270
    • Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, et al. p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation. Mol Syst Biol. 2008;4:229.
    • (2008) Mol Syst Biol , vol.4 , pp. 229
    • Brosh, R.1    Shalgi, R.2    Liran, A.3    Landan, G.4    Korotayev, K.5    Nguyen, G.H.6
  • 46
    • 78649941638 scopus 로고    scopus 로고
    • The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma
    • 3032380 21145484
    • Mestdagh P, Bostrom AK, Impens F, Fredlund E, Van Peer G, De Antonellis P, et al. The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma. Mol Cell. 2010;40:762-73.
    • (2010) Mol Cell , vol.40 , pp. 762-773
    • Mestdagh, P.1    Bostrom, A.K.2    Impens, F.3    Fredlund, E.4    Van Peer, G.5    De Antonellis, P.6
  • 47
    • 39849095077 scopus 로고    scopus 로고
    • E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
    • 18328430
    • Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, De MI, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell. 2008;13:272-86.
    • (2008) Cancer Cell , vol.13 , pp. 272-286
    • Petrocca, F.1    Visone, R.2    Onelli, M.R.3    Shah, M.H.4    Nicoloso, M.S.5    De, M.I.6
  • 48
    • 54249158400 scopus 로고    scopus 로고
    • Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling
    • 18922889
    • Petrocca F, Vecchione A, Croce CM. Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res. 2008;68:8191-4.
    • (2008) Cancer Res , vol.68 , pp. 8191-8194
    • Petrocca, F.1    Vecchione, A.2    Croce, C.M.3
  • 49
    • 78751516162 scopus 로고    scopus 로고
    • MiR-200a prevents renal fibrogenesis through repression of TGF-beta2 expression
    • 3012183 20952520
    • Wang B, Koh P, Winbanks C, Coughlan MT, McClelland A, Watson A, et al. miR-200a prevents renal fibrogenesis through repression of TGF-beta2 expression. Diabetes. 2011;60:280-7.
    • (2011) Diabetes , vol.60 , pp. 280-287
    • Wang, B.1    Koh, P.2    Winbanks, C.3    Coughlan, M.T.4    McClelland, A.5    Watson, A.6
  • 50
    • 79955628616 scopus 로고    scopus 로고
    • P53 spreads out further: Suppression of EMT and stemness by activating miR-200c expression
    • 3203673 21483453
    • Schubert J, Brabletz T. p53 spreads out further: suppression of EMT and stemness by activating miR-200c expression. Cell Res. 2011;21:705-7.
    • (2011) Cell Res , vol.21 , pp. 705-707
    • Schubert, J.1    Brabletz, T.2
  • 51
    • 79952283482 scopus 로고    scopus 로고
    • P53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • 3075845 21336307
    • Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011;13:317-23.
    • (2011) Nat Cell Biol , vol.13 , pp. 317-323
    • Chang, C.J.1    Chao, C.H.2    Xia, W.3    Yang, J.Y.4    Xiong, Y.5    Li, C.W.6
  • 52
    • 84863389824 scopus 로고    scopus 로고
    • Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts
    • 3306299 22438993
    • Zhou L, Wang L, Lu L, Jiang P, Sun H, Wang H. Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts. PLoS One. 2012;7:e33766.
    • (2012) PLoS One , vol.7 , pp. 33766
    • Zhou, L.1    Wang, L.2    Lu, L.3    Jiang, P.4    Sun, H.5    Wang, H.6
  • 53
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • 2653422 18548003
    • Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature. 2008;454:56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 54
    • 77955484492 scopus 로고    scopus 로고
    • Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
    • 2921543 20705240
    • Davis BN, Hilyard AC, Nguyen PH, Lagna G, Hata A. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell. 2010;39:373-84.
    • (2010) Mol Cell , vol.39 , pp. 373-384
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 55
    • 84882726021 scopus 로고    scopus 로고
    • MicroRNA-21: A therapeutic target for reversing drug resistance in cancer
    • 23865553
    • Hong L, Han Y, Zhang Y, Zhang H, Zhao Q, Wu K, et al. MicroRNA-21: a therapeutic target for reversing drug resistance in cancer. Expert Opin Ther Targets. 2013;17:1073-80.
    • (2013) Expert Opin Ther Targets , vol.17 , pp. 1073-1080
    • Hong, L.1    Han, Y.2    Zhang, Y.3    Zhang, H.4    Zhao, Q.5    Wu, K.6
  • 58
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • 18455982
    • Salmena L, Carracedo A, Pandolfi PP. Tenets of PTEN tumor suppression. Cell. 2008;133:403-14.
    • (2008) Cell , vol.133 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 59
    • 38349030742 scopus 로고    scopus 로고
    • New insights into PTEN
    • 18032782
    • Tamguney T, Stokoe D. New insights into PTEN. J Cell Sci. 2007;120:4071-9.
    • (2007) J Cell Sci , vol.120 , pp. 4071-4079
    • Tamguney, T.1    Stokoe, D.2
  • 60
    • 27844445642 scopus 로고    scopus 로고
    • Perturbations of the AKT signaling pathway in human cancer
    • 16288292
    • Altomare DA, Testa JR. Perturbations of the AKT signaling pathway in human cancer. Oncogene. 2005;24:7455-64.
    • (2005) Oncogene , vol.24 , pp. 7455-7464
    • Altomare, D.A.1    Testa, J.R.2
  • 62
    • 67650085171 scopus 로고    scopus 로고
    • TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
    • 2744130 19543271
    • Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I, et al. TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat Cell Biol. 2009;11:881-9.
    • (2009) Nat Cell Biol , vol.11 , pp. 881-889
    • Kato, M.1    Putta, S.2    Wang, M.3    Yuan, H.4    Lanting, L.5    Nair, I.6
  • 63
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • 2578865 18812439
    • Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL, et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA. 2008;14:2348-60.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3    Huang, M.Y.4    Deng, L.5    Wu, Q.L.6
  • 64
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • 18270520
    • Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 2008;18:350-9.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 65
    • 67649783639 scopus 로고    scopus 로고
    • Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma
    • 2695476 19473551
    • Qi L, Bart J, Tan LP, Platteel I, Sluis T, Huitema S, et al. Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma. BMC Cancer. 2009;9:163.
    • (2009) BMC Cancer , vol.9 , pp. 163
    • Qi, L.1    Bart, J.2    Tan, L.P.3    Platteel, I.4    Sluis, T.5    Huitema, S.6
  • 66
    • 50249173450 scopus 로고    scopus 로고
    • MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
    • 2519720 18591254
    • Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, et al. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol. 2008;28:5369-80.
    • (2008) Mol Cell Biol , vol.28 , pp. 5369-5380
    • Gabriely, G.1    Wurdinger, T.2    Kesari, S.3    Esau, C.C.4    Burchard, J.5    Linsley, P.S.6
  • 67
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • 18829576
    • Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008;68:8164-72.
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 68
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • 17681183
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007;133:647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 69
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • 17968323
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene. 2008;27:2128-36.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 70
    • 67349254469 scopus 로고    scopus 로고
    • MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
    • 19302977
    • Li T, Li D, Sha J, Sun P, Huang Y. MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun. 2009;383:280-5.
    • (2009) Biochem Biophys Res Commun , vol.383 , pp. 280-285
    • Li, T.1    Li, D.2    Sha, J.3    Sun, P.4    Huang, Y.5
  • 71
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • 20223231
    • Zhang JG, Wang JJ, Zhao F, Liu Q, Jiang K, Yang GH. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta. 2010;411:846-52.
    • (2010) Clin Chim Acta , vol.411 , pp. 846-852
    • Zhang, J.G.1    Wang, J.J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5    Yang, G.H.6
  • 73
    • 81255205360 scopus 로고    scopus 로고
    • Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis
    • 22094257
    • Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, et al. Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011;20:635-48.
    • (2011) Cancer Cell , vol.20 , pp. 635-648
    • Darido, C.1    Georgy, S.R.2    Wilanowski, T.3    Dworkin, S.4    Auden, A.5    Zhao, Q.6
  • 74
    • 67449164586 scopus 로고    scopus 로고
    • MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor
    • 19509158
    • Li J, Huang H, Sun L, Yang M, Pan C, Chen W, et al. MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor. Clin Cancer Res. 2009;15:3998-4008.
    • (2009) Clin Cancer Res , vol.15 , pp. 3998-4008
    • Li, J.1    Huang, H.2    Sun, L.3    Yang, M.4    Pan, C.5    Chen, W.6
  • 75
    • 77951757309 scopus 로고    scopus 로고
    • The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
    • 2862107 20406979
    • Wong P, Iwasaki M, Somervaille TC, Ficara F, Carico C, Arnold C, et al. The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res. 2010;70:3833-42.
    • (2010) Cancer Res , vol.70 , pp. 3833-3842
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.3    Ficara, F.4    Carico, C.5    Arnold, C.6
  • 76
    • 84871246002 scopus 로고    scopus 로고
    • The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer
    • 10.1038/onc.2012.11
    • Smith AL, Iwanaga R, Drasin DJ, Micalizzi DS, Vartuli RL, Tan AC, et al. The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. Oncogene. 2012. doi: 10.1038/onc.2012.11.
    • (2012) Oncogene
    • Smith, A.L.1    Iwanaga, R.2    Drasin, D.J.3    Micalizzi, D.S.4    Vartuli, R.L.5    Tan, A.C.6    Ford, H.L.7
  • 77
    • 33748302836 scopus 로고    scopus 로고
    • Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
    • 2669546 16878133
    • Dews M, Homayouni A, Yu D, Murphy D, Sevignani C, Wentzel E, et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet. 2006;38:1060-5.
    • (2006) Nat Genet , vol.38 , pp. 1060-1065
    • Dews, M.1    Homayouni, A.2    Yu, D.3    Murphy, D.4    Sevignani, C.5    Wentzel, E.6
  • 78
    • 84880330648 scopus 로고    scopus 로고
    • MiR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS
    • Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, et al. miR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. Mol Carcinog. 2012;28:2167-74.
    • (2012) Mol Carcinog , vol.28 , pp. 2167-2174
    • Wang, Z.1    Liu, M.2    Zhu, H.3    Zhang, W.4    He, S.5    Hu, C.6
  • 79
    • 41149101523 scopus 로고    scopus 로고
    • MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression
    • 2268421 18212054
    • Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM, et al. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol. 2008;28:2167-74.
    • (2008) Mol Cell Biol , vol.28 , pp. 2167-2174
    • Ivanovska, I.1    Ball, A.S.2    Diaz, R.L.3    Magnus, J.F.4    Kibukawa, M.5    Schelter, J.M.6
  • 80
    • 77951026718 scopus 로고    scopus 로고
    • MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene
    • 20354188
    • Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, et al. MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Cancer Res. 2010;70:3119-27.
    • (2010) Cancer Res , vol.70 , pp. 3119-3127
    • Jiang, S.1    Zhang, H.W.2    Lu, M.H.3    He, X.H.4    Li, Y.5    Gu, H.6
  • 81
    • 55849123946 scopus 로고    scopus 로고
    • MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
    • 2573297 18794355
    • Kong W, Yang H, He L, Zhao JJ, Coppola D, Dalton WS, et al. MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol. 2008;28:6773-84.
    • (2008) Mol Cell Biol , vol.28 , pp. 6773-6784
    • Kong, W.1    Yang, H.2    He, L.3    Zhao, J.J.4    Coppola, D.5    Dalton, W.S.6
  • 82
    • 77952944048 scopus 로고    scopus 로고
    • MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
    • 2878550 20371610
    • Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D, et al. MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J Biol Chem. 2010;285:17869-79.
    • (2010) J Biol Chem , vol.285 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3    Guo, J.4    Esposito, N.N.5    Coppola, D.6
  • 83
    • 79961168650 scopus 로고    scopus 로고
    • MiR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
    • 21460854
    • Xiang X, Zhuang X, Ju S, Zhang S, Jiang H, Mu J, et al. miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. Oncogene. 2011;30:3440-53.
    • (2011) Oncogene , vol.30 , pp. 3440-3453
    • Xiang, X.1    Zhuang, X.2    Ju, S.3    Zhang, S.4    Jiang, H.5    Mu, J.6
  • 85
    • 80755145883 scopus 로고    scopus 로고
    • Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer
    • 3184370 21703189
    • Alpini G, Glaser SS, Zhang JP, Francis H, Han Y, Gong J, et al. Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. J Hepatol. 2011;55:1339-45.
    • (2011) J Hepatol , vol.55 , pp. 1339-1345
    • Alpini, G.1    Glaser, S.S.2    Zhang, J.P.3    Francis, H.4    Han, Y.5    Gong, J.6
  • 87
    • 47049125858 scopus 로고    scopus 로고
    • Upregulation of miR-23a 27a 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells
    • 18508316
    • Huang S, He X, Ding J, Liang L, Zhao Y, Zhang Z, et al. Upregulation of miR-23a 27a 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int J Cancer. 2008;123:972-8.
    • (2008) Int J Cancer , vol.123 , pp. 972-978
    • Huang, S.1    He, X.2    Ding, J.3    Liang, L.4    Zhao, Y.5    Zhang, Z.6
  • 88
    • 77950095763 scopus 로고    scopus 로고
    • TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
    • 2845743 20023698
    • Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST, et al. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. 2010;29:1787-97.
    • (2010) Oncogene , vol.29 , pp. 1787-1797
    • Wang, B.1    Hsu, S.H.2    Majumder, S.3    Kutay, H.4    Huang, W.5    Jacob, S.T.6
  • 89
    • 60549090858 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
    • 2754225 19190326
    • Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS, Welch DR. Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res. 2009;69:1279-83.
    • (2009) Cancer Res , vol.69 , pp. 1279-1283
    • Hurst, D.R.1    Edmonds, M.D.2    Scott, G.K.3    Benz, C.C.4    Vaidya, K.S.5    Welch, D.R.6
  • 90
    • 80052319304 scopus 로고    scopus 로고
    • MicroRNA-146a inhibits glioma development by targeting Notch1
    • 3165557 21730286
    • Mei J, Bachoo R, Zhang CL. MicroRNA-146a inhibits glioma development by targeting Notch1. Mol Cell Biol. 2011;31:3584-92.
    • (2011) Mol Cell Biol , vol.31 , pp. 3584-3592
    • Mei, J.1    Bachoo, R.2    Zhang, C.L.3
  • 91
    • 67349107523 scopus 로고    scopus 로고
    • MicroRNA-146b inhibits glioma cell migration and invasion by targeting MMPs
    • 19265686
    • Xia H, Qi Y, Ng SS, Chen X, Li D, Chen S, et al. microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. Brain Res. 2009;1269:158-65.
    • (2009) Brain Res , vol.1269 , pp. 158-165
    • Xia, H.1    Qi, Y.2    Ng, S.S.3    Chen, X.4    Li, D.5    Chen, S.6
  • 92
    • 84862872964 scopus 로고    scopus 로고
    • MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer
    • 22161865
    • Xu B, Wang N, Wang X, Tong N, Shao N, Tao J, et al. MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. Prostate. 2012;72:1171-8.
    • (2012) Prostate , vol.72 , pp. 1171-1178
    • Xu, B.1    Wang, N.2    Wang, X.3    Tong, N.4    Shao, N.5    Tao, J.6
  • 93
    • 40449131878 scopus 로고    scopus 로고
    • Loss of mir-146a function in hormone-refractory prostate cancer
    • 2248249 18174313
    • Lin SL, Chiang A, Chang D, Ying SY. Loss of mir-146a function in hormone-refractory prostate cancer. RNA. 2008;14:417-24.
    • (2008) RNA , vol.14 , pp. 417-424
    • Lin, S.L.1    Chiang, A.2    Chang, D.3    Ying, S.Y.4
  • 94
    • 76749152907 scopus 로고    scopus 로고
    • MiR-146a suppresses invasion of pancreatic cancer cells
    • 2978025 20124483
    • Li Y, Vandenboom TG, Wang Z, Kong D, Ali S, Philip PA, et al. miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res. 2010;70:1486-95.
    • (2010) Cancer Res , vol.70 , pp. 1486-1495
    • Li, Y.1    Vandenboom, T.G.2    Wang, Z.3    Kong, D.4    Ali, S.5    Philip, P.A.6
  • 95
    • 67649511946 scopus 로고    scopus 로고
    • MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines
    • 2890246 19487542
    • Liu X, Yu J, Jiang L, Wang A, Shi F, Ye H, et al. MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics. 2009;6:131-9.
    • (2009) Cancer Genomics Proteomics , vol.6 , pp. 131-139
    • Liu, X.1    Yu, J.2    Jiang, L.3    Wang, A.4    Shi, F.5    Ye, H.6
  • 96
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
    • 1949005 17627278
    • le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J. 2007;26:3699-708.
    • (2007) EMBO J , vol.26 , pp. 3699-3708
    • Le Sage, C.1    Nagel, R.2    Egan, D.A.3    Schrier, M.4    Mesman, E.5    Mangiola, A.6
  • 97
    • 79955419817 scopus 로고    scopus 로고
    • Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs
    • 3339404 21394833
    • Gill JG, Langer EM, Lindsley RC, Cai M, Murphy TL, Kyba M, et al. Snail and the microRNA-200 family act in opposition to regulate epithelial-to- mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells. 2011;29:764-76.
    • (2011) Stem Cells , vol.29 , pp. 764-776
    • Gill, J.G.1    Langer, E.M.2    Lindsley, R.C.3    Cai, M.4    Murphy, T.L.5    Kyba, M.6
  • 98
    • 79955954699 scopus 로고    scopus 로고
    • An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
    • 3093321 21411626
    • Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22:1686-98.
    • (2011) Mol Biol Cell , vol.22 , pp. 1686-1698
    • Gregory, P.A.1    Bracken, C.P.2    Smith, E.3    Bert, A.G.4    Wright, J.A.5    Roslan, S.6
  • 99
    • 78751561435 scopus 로고    scopus 로고
    • MiR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFR1
    • 3232024 21115742
    • Roybal JD, Zang Y, Ahn YH, Yang Y, Gibbons DL, Baird BN, et al. miR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFR1. Mol Cancer Res. 2011;9:25-35.
    • (2011) Mol Cancer Res , vol.9 , pp. 25-35
    • Roybal, J.D.1    Zang, Y.2    Ahn, Y.H.3    Yang, Y.4    Gibbons, D.L.5    Baird, B.N.6
  • 100
    • 80055080741 scopus 로고    scopus 로고
    • MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells
    • 3159440 21511813
    • Feng S, Cong S, Zhang X, Bao X, Wang W, Li H, et al. MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Res. 2011;39:6669-78.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6669-6678
    • Feng, S.1    Cong, S.2    Zhang, X.3    Bao, X.4    Wang, W.5    Li, H.6
  • 101
    • 58149340662 scopus 로고    scopus 로고
    • MiR-192 regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit
    • 2653201 19088023
    • Song B, Wang Y, Kudo K, Gavin EJ, Xi Y, Ju J. miR-192 regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. Clin Cancer Res. 2008;14:8080-6.
    • (2008) Clin Cancer Res , vol.14 , pp. 8080-8086
    • Song, B.1    Wang, Y.2    Kudo, K.3    Gavin, E.J.4    Xi, Y.5    Ju, J.6
  • 102
    • 70449124422 scopus 로고    scopus 로고
    • Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
    • 19701247
    • Li XF, Yan PJ, Shao ZM. Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. Oncogene. 2009;28:3937-48.
    • (2009) Oncogene , vol.28 , pp. 3937-3948
    • Li, X.F.1    Yan, P.J.2    Shao, Z.M.3
  • 103
    • 77957198921 scopus 로고    scopus 로고
    • MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells
    • 20655737
    • Xu C, Liu S, Fu H, Li S, Tie Y, Zhu J, et al. MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells. Eur J Cancer. 2010;46:2828-36.
    • (2010) Eur J Cancer , vol.46 , pp. 2828-2836
    • Xu, C.1    Liu, S.2    Fu, H.3    Li, S.4    Tie, Y.5    Zhu, J.6
  • 104
    • 65549097632 scopus 로고    scopus 로고
    • MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells
    • 19490101
    • Salvi A, Sabelli C, Moncini S, Venturin M, Arici B, Riva P, et al. MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. FEBS J. 2009;276:2966-82.
    • (2009) FEBS J , vol.276 , pp. 2966-2982
    • Salvi, A.1    Sabelli, C.2    Moncini, S.3    Venturin, M.4    Arici, B.5    Riva, P.6
  • 105
    • 44449111693 scopus 로고    scopus 로고
    • MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins
    • 2311339 18390668
    • Sengupta S, den Boon JA, Chen IH, Newton MA, Stanhope SA, Cheng YJ, et al. MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008;105:5874-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5874-5878
    • Sengupta, S.1    Den Boon, J.A.2    Chen, I.H.3    Newton, M.A.4    Stanhope, S.A.5    Cheng, Y.J.6
  • 106
  • 107
    • 77954427807 scopus 로고    scopus 로고
    • MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells
    • 19830559
    • Hu M, Xia M, Chen X, Lin Z, Xu Y, Ma Y, et al. MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells. Dig Dis Sci. 2010;55:2365-72.
    • (2010) Dig Dis Sci , vol.55 , pp. 2365-2372
    • Hu, M.1    Xia, M.2    Chen, X.3    Lin, Z.4    Xu, Y.5    Ma, Y.6
  • 108
    • 77649241350 scopus 로고    scopus 로고
    • Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia
    • 2840429 20133587
    • Mi S, Li Z, Chen P, He C, Cao D, Elkahloun A, et al. Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. Proc Natl Acad Sci U S A. 2010;107:3710-5.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 3710-3715
    • Mi, S.1    Li, Z.2    Chen, P.3    He, C.4    Cao, D.5    Elkahloun, A.6
  • 109
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • 17110329
    • Gupta GP, Massague J. Cancer metastasis: building a framework. Cell. 2006;127:679-95.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 110
    • 0037708932 scopus 로고    scopus 로고
    • Metastatic potential: Generic predisposition of the primary tumor or rare, metastatic variants-or both?
    • 12837240
    • Hynes RO. Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both? Cell. 2003;113:821-3.
    • (2003) Cell , vol.113 , pp. 821-823
    • Hynes, R.O.1
  • 111
    • 58649089340 scopus 로고    scopus 로고
    • Role of cancer microenvironment in metastasis: Focus on colon cancer
    • 2654352 19308686
    • Gout S, Huot J. Role of cancer microenvironment in metastasis: focus on colon cancer. Cancer Microenviron. 2008;1:69-83.
    • (2008) Cancer Microenviron , vol.1 , pp. 69-83
    • Gout, S.1    Huot, J.2
  • 112
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • 21436443
    • Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331:1559-64.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 113
    • 77149174482 scopus 로고    scopus 로고
    • The microRNA network and tumor metastasis
    • 19935707
    • Zhang H, Li Y, Lai M. The microRNA network and tumor metastasis. Oncogene. 2010;29:937-48.
    • (2010) Oncogene , vol.29 , pp. 937-948
    • Zhang, H.1    Li, Y.2    Lai, M.3
  • 114
    • 34250738303 scopus 로고    scopus 로고
    • Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling
    • 2043381 17587819
    • Ahmed S, Nawshad A. Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling. Cells Tissues Organs. 2007;185:131-45.
    • (2007) Cells Tissues Organs , vol.185 , pp. 131-145
    • Ahmed, S.1    Nawshad, A.2
  • 115
    • 47549098328 scopus 로고    scopus 로고
    • New insights of epithelial-mesenchymal transition in cancer metastasis
    • Wu Y, Zhou BP. New insights of epithelial-mesenchymal transition in cancer metastasis. Acta Biochim Biophys Sin (Shanghai). 2008;40:643-50.
    • (2008) Acta Biochim Biophys Sin (Shanghai) , vol.40 , pp. 643-650
    • Wu, Y.1    Zhou, B.P.2
  • 116
    • 56749095797 scopus 로고    scopus 로고
    • Transcriptional regulation of cell polarity in EMT and cancer
    • 19029937
    • Moreno-Bueno G, Portillo F, Cano A. Transcriptional regulation of cell polarity in EMT and cancer. Oncogene. 2008;27:6958-69.
    • (2008) Oncogene , vol.27 , pp. 6958-6969
    • Moreno-Bueno, G.1    Portillo, F.2    Cano, A.3
  • 117
    • 16344378397 scopus 로고    scopus 로고
    • TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
    • 1073677 15689496
    • Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A. TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol Biol Cell. 2005;16:1987-2002.
    • (2005) Mol Biol Cell , vol.16 , pp. 1987-2002
    • Valcourt, U.1    Kowanetz, M.2    Niimi, H.3    Heldin, C.H.4    Moustakas, A.5
  • 118
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • 3258899 18411277
    • Korpal M, Lee ES, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem. 2008;283:14910-4.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 119
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • 18829540
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008;68:7846-54.
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6
  • 120
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • 18376396
    • Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10:593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 121
    • 85011936092 scopus 로고    scopus 로고
    • The emerging role of miR-200 family of microRNAs in epithelial- mesenchymal transition and cancer metastasis
    • 3532896 19182522
    • Korpal M, Kang Y. The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biol. 2008;5:115-9.
    • (2008) RNA Biol , vol.5 , pp. 115-119
    • Korpal, M.1    Kang, Y.2
  • 122
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
    • 15761148
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science. 2005;307:1603-9.
    • (2005) Science , vol.307 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.R.4    Zhang, Y.5    Wrana, J.L.6
  • 125
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • 11001068
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407:249-57.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 126
    • 58149260186 scopus 로고    scopus 로고
    • Smad3 mediates immediate early induction of Id1 by TGF-beta
    • 19079362
    • Liang YY, Brunicardi FC, Lin X. Smad3 mediates immediate early induction of Id1 by TGF-beta. Cell Res. 2009;19:140-8.
    • (2009) Cell Res , vol.19 , pp. 140-148
    • Liang, Y.Y.1    Brunicardi, F.C.2    Lin, X.3
  • 128
    • 54249139202 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium
    • 18922939
    • Benetti A, Berenzi A, Gambarotti M, Garrafa E, Gelati M, Dessy E, et al. Transforming growth factor-beta1 and CD105 promote the migration of hepatocellular carcinoma-derived endothelium. Cancer Res. 2008;68:8626-34.
    • (2008) Cancer Res , vol.68 , pp. 8626-8634
    • Benetti, A.1    Berenzi, A.2    Gambarotti, M.3    Garrafa, E.4    Gelati, M.5    Dessy, E.6
  • 129
    • 67649998366 scopus 로고    scopus 로고
    • MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice
    • 19460962
    • Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, et al. MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science. 2009;324:1710-3.
    • (2009) Science , vol.324 , pp. 1710-1713
    • Bonauer, A.1    Carmona, G.2    Iwasaki, M.3    Mione, M.4    Koyanagi, M.5    Fischer, A.6
  • 130
    • 61949361268 scopus 로고    scopus 로고
    • MicroRNAs as novel regulators of angiogenesis
    • 2760389 19246688
    • Suarez Y, Sessa WC. MicroRNAs as novel regulators of angiogenesis. Circ Res. 2009;104:442-54.
    • (2009) Circ Res , vol.104 , pp. 442-454
    • Suarez, Y.1    Sessa, W.C.2
  • 131
    • 0036142371 scopus 로고    scopus 로고
    • Transforming growth factor beta induces vascular endothelial growth factor elaboration from pleural mesothelial cells in vivo and in vitro
    • 11779736
    • Gary Lee YC, Melkerneker D, Thompson PJ, Light RW, Lane KB. Transforming growth factor beta induces vascular endothelial growth factor elaboration from pleural mesothelial cells in vivo and in vitro. Am J Respir Crit Care Med. 2002;165:88-94.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 88-94
    • Gary Lee, Y.C.1    Melkerneker, D.2    Thompson, P.J.3    Light, R.W.4    Lane, K.B.5
  • 132
    • 0037049982 scopus 로고    scopus 로고
    • Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis
    • 11774256
    • Breier G, Blum S, Peli J, Groot M, Wild C, Risau W, et al. Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis. Int J Cancer. 2002;97:142-8.
    • (2002) Int J Cancer , vol.97 , pp. 142-148
    • Breier, G.1    Blum, S.2    Peli, J.3    Groot, M.4    Wild, C.5    Risau, W.6
  • 133
    • 47949083323 scopus 로고    scopus 로고
    • PGE2 induces angiogenesis via MT1-MMP-mediated activation of the TGFbeta/Alk5 signaling pathway
    • 18541723
    • Alfranca A, Lopez-Oliva JM, Genis L, Lopez-Maderuelo D, Mirones I, Salvado D, et al. PGE2 induces angiogenesis via MT1-MMP-mediated activation of the TGFbeta/Alk5 signaling pathway. Blood. 2008;112:1120-8.
    • (2008) Blood , vol.112 , pp. 1120-1128
    • Alfranca, A.1    Lopez-Oliva, J.M.2    Genis, L.3    Lopez-Maderuelo, D.4    Mirones, I.5    Salvado, D.6
  • 134
    • 0024708518 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget S. The distribution of secondary growths in cancer of the breast. Cancer Metastasis Rev. 1889;8:98-101.
    • (1889) Cancer Metastasis Rev , vol.8 , pp. 98-101
    • Paget, S.1
  • 135
    • 33845811455 scopus 로고    scopus 로고
    • Preparing the "soil": The premetastatic niche
    • 2952469 17145848
    • Kaplan RN, Rafii S, Lyden D. Preparing the "soil": the premetastatic niche. Cancer Res. 2006;66:11089-93.
    • (2006) Cancer Res , vol.66 , pp. 11089-11093
    • Kaplan, R.N.1    Rafii, S.2    Lyden, D.3
  • 136
    • 79953300698 scopus 로고    scopus 로고
    • The seed and soil hypothesis revisited - The role of tumor-stroma interactions in metastasis to different organs
    • 3075088 21365651
    • Langley RR, Fidler IJ. The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer. 2011;128:2527-35.
    • (2011) Int J Cancer , vol.128 , pp. 2527-2535
    • Langley, R.R.1    Fidler, I.J.2
  • 137
    • 0018875604 scopus 로고
    • Role of organ selectivity in the determination of metastatic patterns of B16 melanoma
    • 7388794
    • Hart IR, Fidler IJ. Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res. 1980;40:2281-7.
    • (1980) Cancer Res , vol.40 , pp. 2281-2287
    • Hart, I.R.1    Fidler, I.J.2
  • 138
    • 41149157649 scopus 로고    scopus 로고
    • TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4
    • 2390892 18394990
    • Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR, et al. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell. 2008;133:66-77.
    • (2008) Cell , vol.133 , pp. 66-77
    • Padua, D.1    Zhang, X.H.2    Wang, Q.3    Nadal, C.4    Gerald, W.L.5    Gomis, R.R.6
  • 139
    • 70449526719 scopus 로고    scopus 로고
    • Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
    • 2773241 19838175
    • Giampieri S, Manning C, Hooper S, Jones L, Hill CS, Sahai E. Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol. 2009;11:1287-96.
    • (2009) Nat Cell Biol , vol.11 , pp. 1287-1296
    • Giampieri, S.1    Manning, C.2    Hooper, S.3    Jones, L.4    Hill, C.S.5    Sahai, E.6
  • 140
    • 54249097017 scopus 로고    scopus 로고
    • Runx2 transcriptional activation of Indian hedgehog and a downstream bone metastatic pathway in breast cancer cells
    • 2596479 18829534
    • Pratap J, Wixted JJ, Gaur T, Zaidi SK, Dobson J, Gokul KD, et al. Runx2 transcriptional activation of Indian hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res. 2008;68:7795-802.
    • (2008) Cancer Res , vol.68 , pp. 7795-7802
    • Pratap, J.1    Wixted, J.J.2    Gaur, T.3    Zaidi, S.K.4    Dobson, J.5    Gokul, K.D.6
  • 141
    • 79551514021 scopus 로고    scopus 로고
    • TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling
    • 3077118 21189326
    • Johnson RW, Nguyen MP, Padalecki SS, Grubbs BG, Merkel AR, Oyajobi BO, et al. TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling. Cancer Res. 2011;71:822-31.
    • (2011) Cancer Res , vol.71 , pp. 822-831
    • Johnson, R.W.1    Nguyen, M.P.2    Padalecki, S.S.3    Grubbs, B.G.4    Merkel, A.R.5    Oyajobi, B.O.6
  • 142
    • 79953686494 scopus 로고    scopus 로고
    • A microRNA expression signature of osteoclastogenesis
    • 3072882 21273303
    • Sugatani T, Vacher J, Hruska KA. A microRNA expression signature of osteoclastogenesis. Blood. 2011;117:3648-57.
    • (2011) Blood , vol.117 , pp. 3648-3657
    • Sugatani, T.1    Vacher, J.2    Hruska, K.A.3
  • 143
    • 84860473453 scopus 로고    scopus 로고
    • MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway
    • 3334516 22382496
    • Lynch J, Fay J, Meehan M, Bryan K, Watters KM, Murphy DM, et al. MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway. Carcinogenesis. 2012;33:976-85.
    • (2012) Carcinogenesis , vol.33 , pp. 976-985
    • Lynch, J.1    Fay, J.2    Meehan, M.3    Bryan, K.4    Watters, K.M.5    Murphy, D.M.6
  • 144
    • 84859510049 scopus 로고    scopus 로고
    • MicroRNA-34a modulates cytoskeletal dynamics through regulating RhoA/Rac1 cross-talk in chondroblasts
    • 3320999 22351754
    • Kim D, Song J, Kim S, Park HM, Chun CH, Sonn J, et al. MicroRNA-34a modulates cytoskeletal dynamics through regulating RhoA/Rac1 cross-talk in chondroblasts. J Biol Chem. 2012;287:12501-9.
    • (2012) J Biol Chem , vol.287 , pp. 12501-12509
    • Kim, D.1    Song, J.2    Kim, S.3    Park, H.M.4    Chun, C.H.5    Sonn, J.6
  • 145
    • 84870924300 scopus 로고    scopus 로고
    • TGF-β-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38MAPK, MAP2K4 and MAP2K7
    • 23034448
    • Min S, Li L, Zhang M, Zhang Y, Liang X, Xie Y, et al. TGF-β-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38MAPK, MAP2K4 and MAP2K7. Genes Immun. 2012;13:621-31.
    • (2012) Genes Immun. , vol.13 , pp. 621-631
    • Min, S.1    Li, L.2    Zhang, M.3    Zhang, Y.4    Liang, X.5    Xie, Y.6
  • 146
    • 58249121581 scopus 로고    scopus 로고
    • A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle
    • 2746005 19117988
    • Cohen EE, Zhu H, Lingen MW, Martin LE, Kuo WL, Choi EA, et al. A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Res. 2009;69:65-74.
    • (2009) Cancer Res , vol.69 , pp. 65-74
    • Cohen, E.E.1    Zhu, H.2    Lingen, M.W.3    Martin, L.E.4    Kuo, W.L.5    Choi, E.A.6
  • 147
    • 84866116748 scopus 로고    scopus 로고
    • MicroRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase Cε
    • 3307861 22158047
    • Datta J, Smith A, Lang JC, Islam M, Dutt D, Teknos TN, et al. microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase Cε. Oncogene. 2012;31:4045-53.
    • (2012) Oncogene , vol.31 , pp. 4045-4053
    • Datta, J.1    Smith, A.2    Lang, J.C.3    Islam, M.4    Dutt, D.5    Teknos, T.N.6
  • 148
    • 84875448088 scopus 로고    scopus 로고
    • MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon)
    • 3605692 23364795
    • Körner C, Keklikoglou I, Bender C, Wörner A, Münstermann E, Wiemann S. MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKCepsilon). J Biol Chem. 2013;288:8750-61.
    • (2013) J Biol Chem , vol.288 , pp. 8750-8761
    • Körner, C.1    Keklikoglou, I.2    Bender, C.3    Wörner, A.4    Münstermann, E.5    Wiemann, S.6
  • 149
    • 84857578369 scopus 로고    scopus 로고
    • Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon
    • 3288050 22384062
    • Caino MC, Lopez-Haber C, Kissil JL, Kazanietz MG. Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon. PLoS One. 2012;7(2):e31714.
    • (2012) PLoS One , vol.7 , Issue.2 , pp. 31714
    • Caino, M.C.1    Lopez-Haber, C.2    Kissil, J.L.3    Kazanietz, M.G.4
  • 150
    • 84878682019 scopus 로고    scopus 로고
    • Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions
    • 3667718 23552692
    • Jung HM, Patel RS, Phillips BL, Wang H, Cohen DM, Reinhold WC, et al. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions. Mol Biol Cell. 2013;24:1638-48.
    • (2013) Mol Biol Cell , vol.24 , pp. 1638-1648
    • Jung, H.M.1    Patel, R.S.2    Phillips, B.L.3    Wang, H.4    Cohen, D.M.5    Reinhold, W.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.