Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 8, 2010, Pages 3710-3715

  Mi, Shuangli ^a,i   Li, Zejuan ^a   Chen, Ping ^a   He, Chunjiang ^a   Cao, Donglin ^a,b   Elkahloun, Abdel ^c   Lu, Jun ^d   Pelloso, Luis A ^a,e   Wunderlich, Mark ^f   Huang, Hao ^a   Luo, Roger T ^a   Sun, Miao ^a   He, Miao ^a,g   Neilly, Mary Beth ^a   Zeleznik Le, Nancy J ^h   Thirman, Michael J ^a   Mulloy, James C ^f   Liu, Paul P ^c   Rowley, Janet D ^a   Chen, Jianjun ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d YALE UNIVERSITY   (United States)

^e FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^g LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^h CHINA MEDICAL UNIVERSITY   (China)

ⁱ Chinese Academy of Sciences and China National Center for Bioinformation   (China)

Author keywords

Cell apoptosis and viability; Colony forming replating assay; Gene regulation; MiRNA target; MLL binding

Indexed keywords

HISTONE H3; MESSENGER RNA; MICRORNA; MIXED LINEAGE LEUKEMIA PROTEIN;

ACETYLATION; ACUTE LEUKEMIA; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLONY FORMING UNIT; CONTROLLED STUDY; FUSION GENE; GENE AMPLIFICATION; GENE CLUSTER; GENE IDENTIFICATION; GENE LOCUS; GENE NUMBER; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; UPREGULATION; WILD TYPE;

ANIMALS; CELL LINE, TUMOR; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, LEUKEMIC; HELA CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICRORNAS; MULTIGENE FAMILY;

EID: 77649241350     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914900107     Document Type: Article

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