-
2
-
-
33745699726
-
Protein kinase C ζ mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase
-
Cohen EE, Lingen MW, Zhu B, et al. Protein kinase C ζ mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase. Cancer Res 2006;66:6296-303.
-
(2006)
Cancer Res
, vol.66
, pp. 6296-6303
-
-
Cohen, E.E.1
Lingen, M.W.2
Zhu, B.3
-
3
-
-
33947603008
-
Protein kinase C and other diacylglycerol effectors in cancer
-
Griner EM, Kazanietz MG. Protein kinase C and other diacylglycerol effectors in cancer. Nat Rev Cancer 2007;7:281-94.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 281-294
-
-
Griner, E.M.1
Kazanietz, M.G.2
-
4
-
-
34249099952
-
Overexpression of protein kinase C α mRNA in human hepatocellular carcinoma: A potential marker of disease prognosis
-
Wu TT, Hsieh YH, Wu CC, Hsieh YS, Huang CY, Liu JY. Overexpression of protein kinase C α mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis. Clin Chim Acta 2007;382:54-8.
-
(2007)
Clin Chim Acta
, vol.382
, pp. 54-58
-
-
Wu, T.T.1
Hsieh, Y.H.2
Wu, C.C.3
Hsieh, Y.S.4
Huang, C.Y.5
Liu, J.Y.6
-
5
-
-
0028609621
-
Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-α
-
Dlugosz AA, Cheng C, Williams EK, Dharia AG, Denning MF, Yuspa SH. Alterations in murine keratinocyte differentiation induced by activated rasHa genes are mediated by protein kinase C-α. Cancer Res 1994;54:6413-20.
-
(1994)
Cancer Res
, vol.54
, pp. 6413-6420
-
-
Dlugosz, A.A.1
Cheng, C.2
Williams, E.K.3
Dharia, A.G.4
Denning, M.F.5
Yuspa, S.H.6
-
6
-
-
0033961302
-
In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo
-
Chmura SJ, Dolan ME, Cha A, Mauceri HJ, Kufe DW, Weichselbaum RR. In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo. Clin Cancer Res 2000;6:737-42.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 737-742
-
-
Chmura, S.J.1
Dolan, M.E.2
Cha, A.3
Mauceri, H.J.4
Kufe, D.W.5
Weichselbaum, R.R.6
-
7
-
-
40549108563
-
Cell Cycle Regulation of DNA Replication
-
Sclafani RA, Holzen TM. Cell Cycle Regulation of DNA Replication. Annu Rev Genet 2007;41:237-80.
-
(2007)
Annu Rev Genet
, vol.41
, pp. 237-280
-
-
Sclafani, R.A.1
Holzen, T.M.2
-
9
-
-
33846846397
-
MicroRNA and cancer: Current status and prospective
-
Wu W, Sun M, Zou GM, Chen J. MicroRNA and cancer: current status and prospective. Int J Cancer 2007;120:953-60.
-
(2007)
Int J Cancer
, vol.120
, pp. 953-960
-
-
Wu, W.1
Sun, M.2
Zou, G.M.3
Chen, J.4
-
10
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007;447:1130-4.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
-
11
-
-
33947224690
-
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
-
Linsley PS, Schelter J, Burchard J, et al. Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol 2007;27:2240-52.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2240-2252
-
-
Linsley, P.S.1
Schelter, J.2
Burchard, J.3
-
12
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-43.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
13
-
-
34047267329
-
An E2F/miR-20a autoregulatory feedback loop
-
Sylvestre Y, De Guire V, Querido E, et al. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 2007;282:2135-43.
-
(2007)
J Biol Chem
, vol.282
, pp. 2135-2143
-
-
Sylvestre, Y.1
De Guire, V.2
Querido, E.3
-
14
-
-
34047264639
-
Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
-
Woods K, Thomson JM, Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007;282:2130-4.
-
(2007)
J Biol Chem
, vol.282
, pp. 2130-2134
-
-
Woods, K.1
Thomson, J.M.2
Hammond, S.M.3
-
15
-
-
32944464047
-
Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma
-
Slebos RJ, Yi Y, Ely K, et al. Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma. Clin Cancer Res 2006;12:701-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 701-709
-
-
Slebos, R.J.1
Yi, Y.2
Ely, K.3
-
16
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001;98:5116-21.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
17
-
-
33748057486
-
Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-κB signaling as characteristics of a high-risk head and neck squamous cell carcinoma
-
Chung CH, Parker JS, Ely K, et al. Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-κB signaling as characteristics of a high-risk head and neck squamous cell carcinoma. Cancer Res 2006;66:8210-8.
-
(2006)
Cancer Res
, vol.66
, pp. 8210-8218
-
-
Chung, C.H.1
Parker, J.S.2
Ely, K.3
-
18
-
-
0036082364
-
-
Shapiro BA, Ray S, Jung E, Allred WT, Bollag WB. Putative conventional protein kinase C inhibitor Godecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro- 13-methyl-5-oxo-5H-indolo(2,3-a)py rrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes. J Pharmacol Exp Ther 2002;302:352-8.
-
Shapiro BA, Ray S, Jung E, Allred WT, Bollag WB. Putative conventional protein kinase C inhibitor Godecke 6976 [12-(2-cyanoethyl)-6,7,12,13-tetrahydro- 13-methyl-5-oxo-5H-indolo(2,3-a)py rrolo(3,4-c)-carbazole] stimulates transglutaminase activity in primary mouse epidermal keratinocytes. J Pharmacol Exp Ther 2002;302:352-8.
-
-
-
-
19
-
-
0031038588
-
Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase
-
Cai H, Smola U, Wixler V, et al. Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase. Mol Cell Biol 1997;17:732-41.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 732-741
-
-
Cai, H.1
Smola, U.2
Wixler, V.3
-
20
-
-
0029617910
-
Evidence for a role of MEK and MAPK during signal transduction by protein kinase Cζ
-
Berra E, Diaz-Meco MT, Lozano J, et al. Evidence for a role of MEK and MAPK during signal transduction by protein kinase Cζ. EMBO J 1995;14:6157-63.
-
(1995)
EMBO J
, vol.14
, pp. 6157-6163
-
-
Berra, E.1
Diaz-Meco, M.T.2
Lozano, J.3
-
21
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005;102:15545-50.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
22
-
-
0038356681
-
An E2F site in the 5′-promoter region contributes to serum-dependent up-regulation of the human proliferating cell nuclear antigen gene
-
Li YY, Wang L, Lu CD. An E2F site in the 5′-promoter region contributes to serum-dependent up-regulation of the human proliferating cell nuclear antigen gene. FEBS Lett 2003;544:112-8.
-
(2003)
FEBS Lett
, vol.544
, pp. 112-118
-
-
Li, Y.Y.1
Wang, L.2
Lu, C.D.3
-
23
-
-
0037053322
-
The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes
-
Noya F, Chien WM, Wu X, et al. The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes. J Biol Chem 2002;277:17271-80.
-
(2002)
J Biol Chem
, vol.277
, pp. 17271-17280
-
-
Noya, F.1
Chien, W.M.2
Wu, X.3
-
24
-
-
0033535590
-
Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F
-
Ohtani K, Iwanaga R, Nakamura M, et al. Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F. Oncogene 1999;18:2299-309.
-
(1999)
Oncogene
, vol.18
, pp. 2299-2309
-
-
Ohtani, K.1
Iwanaga, R.2
Nakamura, M.3
-
25
-
-
34249066085
-
PCNA, the maestro of the replication fork
-
Moldovan GL, Pfander B, Jentsch S. PCNA, the maestro of the replication fork. Cell 2007;129:665-79.
-
(2007)
Cell
, vol.129
, pp. 665-679
-
-
Moldovan, G.L.1
Pfander, B.2
Jentsch, S.3
-
26
-
-
0032143922
-
The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation
-
Garcia-Paramio P, Cabrerizo Y, Bornancin F, Parker PJ. The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation. Biochem J 1998;333:631-6.
-
(1998)
Biochem J
, vol.333
, pp. 631-636
-
-
Garcia-Paramio, P.1
Cabrerizo, Y.2
Bornancin, F.3
Parker, P.J.4
-
27
-
-
0642376906
-
Protein kinase Cζ (PKCζ): Activation mechanisms and cellular functions
-
Hirai T, Chida K. Protein kinase Cζ (PKCζ): activation mechanisms and cellular functions. J Biochem Tokyo 2003;133:1-7.
-
(2003)
J Biochem Tokyo
, vol.133
, pp. 1-7
-
-
Hirai, T.1
Chida, K.2
-
28
-
-
34249079154
-
Network motifs: Theory and experimental approaches
-
Alon U. Network motifs: theory and experimental approaches. Nat Rev Genet 2007;8:450-61.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 450-461
-
-
Alon, U.1
-
29
-
-
18744396337
-
Frequent deletions and down-regulation of microRNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of microRNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002;99:15524-9.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
30
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 2005;102:13944-9.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
-
31
-
-
18844459384
-
-
Bottoni A, Piccin D, Tagliati F, Luchin A, Zatelli MC, degli Uberti EC. miR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell Physiol 2005;204:280-5.
-
Bottoni A, Piccin D, Tagliati F, Luchin A, Zatelli MC, degli Uberti EC. miR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell Physiol 2005;204:280-5.
-
-
-
-
32
-
-
33750600178
-
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
-
Roldo C, Missiaglia E, Hagan JP, et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 2006;24:4677-84.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4677-4684
-
-
Roldo, C.1
Missiaglia, E.2
Hagan, J.P.3
-
33
-
-
0035657643
-
Protein kinase C inhibitors as novel anticancer drugs
-
Goekjian PG, Jirousek MR. Protein kinase C inhibitors as novel anticancer drugs. Expert Opin Investig Drugs 2001;10:2117-40.
-
(2001)
Expert Opin Investig Drugs
, vol.10
, pp. 2117-2140
-
-
Goekjian, P.G.1
Jirousek, M.R.2
-
34
-
-
33644649000
-
Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCα
-
Bokhari SM, Zhou L, Karasek MA, Paturi SG, Chaudhuri V. Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCα. J Invest Dermatol 2006;126:460-7.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 460-467
-
-
Bokhari, S.M.1
Zhou, L.2
Karasek, M.A.3
Paturi, S.G.4
Chaudhuri, V.5
-
35
-
-
12444250688
-
Protein kinase Cα-mediated chemotaxis of neutrophils requires NF-κB activity but is independent of TNF α signaling in mouse skin in vivo
-
Cataisson C, Pearson AJ, Torgerson S, Nedospasov SA, Yuspa SH. Protein kinase Cα-mediated chemotaxis of neutrophils requires NF-κB activity but is independent of TNF α signaling in mouse skin in vivo. J Immunol 2005;174:1686-92.
-
(2005)
J Immunol
, vol.174
, pp. 1686-1692
-
-
Cataisson, C.1
Pearson, A.J.2
Torgerson, S.3
Nedospasov, S.A.4
Yuspa, S.H.5
-
36
-
-
0037603294
-
Genomic structure and promoter analysis of PKC-δ
-
Suh KS, Tatunchak TT, Crutchley JM, Edwards LE, Marin KG, Yuspa SH. Genomic structure and promoter analysis of PKC-δ. Genomics 2003;82:57-67.
-
(2003)
Genomics
, vol.82
, pp. 57-67
-
-
Suh, K.S.1
Tatunchak, T.T.2
Crutchley, J.M.3
Edwards, L.E.4
Marin, K.G.5
Yuspa, S.H.6
-
37
-
-
18844473151
-
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
-
Sun Z, Arendt CW, Ellmeier W, et al. PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes. Nature 2000;404:402-7.
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
-
39
-
-
0141446032
-
Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes
-
Soh JW, Weinstein IB. Roles of specific isoforms of protein kinase C in the transcriptional control of cyclin D1 and related genes. J Biol Chem 2003;278:34709-16.
-
(2003)
J Biol Chem
, vol.278
, pp. 34709-34716
-
-
Soh, J.W.1
Weinstein, I.B.2
-
40
-
-
0031034522
-
Definition by specific antisense oligonucleotides of a role for protein kinase Cα in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes
-
Lee YS, Dlugosz AA, McKay R, Dean NM, Yuspa SH. Definition by specific antisense oligonucleotides of a role for protein kinase Cα in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes. Mol Carcinog 1997;18:44-53.
-
(1997)
Mol Carcinog
, vol.18
, pp. 44-53
-
-
Lee, Y.S.1
Dlugosz, A.A.2
McKay, R.3
Dean, N.M.4
Yuspa, S.H.5
-
41
-
-
0036915652
-
Activation of protein kinase C triggers irreversible cell cycle withdrawal in human keratinocytes
-
Tibudan SS, Wang Y, Denning MF. Activation of protein kinase C triggers irreversible cell cycle withdrawal in human keratinocytes. J Invest Dermatol 2002;119:1282-9.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 1282-1289
-
-
Tibudan, S.S.1
Wang, Y.2
Denning, M.F.3
-
42
-
-
0037401924
-
Role of protein kinase C α in calcium induced keratinocyte differentiation: Defective regulation in squamous cell carcinoma
-
Yang LC, Ng DC, Bikle DD. Role of protein kinase C α in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma. J Cell Physiol 2003;195:249-59.
-
(2003)
J Cell Physiol
, vol.195
, pp. 249-259
-
-
Yang, L.C.1
Ng, D.C.2
Bikle, D.D.3
-
43
-
-
33846018073
-
Kinase-independent function of cyclin E
-
Geng Y, Lee YM, Welcker M, et al. Kinase-independent function of cyclin E. Mol Cell 2007;25:127-39.
-
(2007)
Mol Cell
, vol.25
, pp. 127-139
-
-
Geng, Y.1
Lee, Y.M.2
Welcker, M.3
-
44
-
-
18344381018
-
Cyclin E in normal and neoplastic cell cycles
-
Hwang HC, Clurman BE. Cyclin E in normal and neoplastic cell cycles. Oncogene 2005;24:2776-86.
-
(2005)
Oncogene
, vol.24
, pp. 2776-2786
-
-
Hwang, H.C.1
Clurman, B.E.2
-
45
-
-
0033626036
-
The expression of cyclins D1 and E in predicting short-term survival in squamous cell carcinoma of the lung
-
Anton RC, Coffey DM, Gondo MM, Stephenson MA, Brown RW, Cagle PT. The expression of cyclins D1 and E in predicting short-term survival in squamous cell carcinoma of the lung. Mod Pathol 2000;13:1167-72.
-
(2000)
Mod Pathol
, vol.13
, pp. 1167-1172
-
-
Anton, R.C.1
Coffey, D.M.2
Gondo, M.M.3
Stephenson, M.A.4
Brown, R.W.5
Cagle, P.T.6
-
46
-
-
0033730358
-
Prognostic significance of cyclin E overexpression in laryngeal squamous cell carcinomas
-
Dong Y, Sui L, Tai Y, Sugimoto K, Hirao T, Tokuda M. Prognostic significance of cyclin E overexpression in laryngeal squamous cell carcinomas. Clin Cancer Res 2000;6:4253-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4253-4258
-
-
Dong, Y.1
Sui, L.2
Tai, Y.3
Sugimoto, K.4
Hirao, T.5
Tokuda, M.6
|