A role for the TGFβ-Par6 polarity pathway in breast cancer progression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 33, 2009, Pages 14028-14033

  Viloria Petit, Alicia M ^a   David, Laurent ^a   Jun, Yong Jia ^a   Erdemir, Tuba ^a   Bane, Anita L ^a,b   Pinnaduwage, Dushanthi ^a   Roncari, Luba ^a   Narimatsu, Masahiro ^a   Bose, Rohit ^a,b   Moffat, Jason ^b   Wong, John W ^b,c   Kerbelh, Robert S ^c,d   O'Malley, Frances P ^a,b   Andrulis, Irene L ^a,b   Wrana, Jeffrey L ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Cell polarity; Epithelial plasticity; Epithelial to mesenchymal transition; Metastasis; Tumor invasion

Indexed keywords

PROTEIN ZO1; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; PAR6 PROTEIN, MOUSE; PARD6A PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER GROWTH; CELL POLARITY; CELL STRUCTURE; CONTROLLED STUDY; GENE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; MESENCHYME CELL; MOUSE; NONHUMAN; PAR6 GENE; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE MICROARRAY; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; DISEASE COURSE; EXPERIMENTAL NEOPLASM; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; METABOLISM; METASTASIS; METHODOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BREAST NEOPLASMS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; NEOPLASM METASTASIS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 69549128378     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906796106     Document Type: Article

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