Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor β signaling

Cancer Research

Volumn 68, Issue 20, 2008, Pages 8191-8194

  Petrocca, Fabio ^a   Vecchione, Andrea ^a   Croce, Carlo M ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; CANCER CELL; CANCER DIAGNOSIS; CANCER INHIBITION; CELL CYCLE ARREST; CENTRAL NERVOUS SYSTEM; GASTROINTESTINAL TUMOR; HOMEOSTASIS; HUMAN; LIVER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA-BINDING PROTEINS; E2F1 TRANSCRIPTION FACTOR; GENES, MYC; HUMANS; MEMBRANE PROTEINS; MICRORNAS; MULTIGENE FAMILY; NEOPLASMS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEINS;

EID: 54249158400     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1768     Document Type: Review

References (22)

1. Mishra L, Shetty K, Tang Y, et al. The role of TGF-β and Wnt signaling in gastrointestinal stem cells and cancer. Oncogene 2005;24:5775-89.
2. van den Brink GR, Offerhaus GJ. The morphogenetic code and colon cancer development. Cancer Cell 2007;11:109-17.
3. Ohgushi M, Kuroki S, Fukamachi H, et al. Transforming growth factor β-dependent sequential activation of Smad, BIM, and caspase-9 mediates physiological apoptosis in gastric epithelial cells. Mol Cell Biol 2005;25:10017-28.
4. Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2008;131:1109-23.
5. Poy MN, Eliasson L, Krutzfeldt J, et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 2004;11:226-30.
6. le Sage C, Nagel R, Egan DA, et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J 2007;8:3699-708.
7. Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005;120:15-20.
8. Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002;99:15524-9.
9. Volinia S, Calin GA, Liu C-G, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006;103:2257-61.
10. Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature 2005;435:834-8.
11. Rosenfeld N, Aharonov R, Meiri E, et al. MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol 2008;26:462-9.
12. He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-33.
13. Costinean S, Zanesi N, Pekarsky Y, et al. Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A 2006;103:7024-9.
14. Petrocca F, Visone R, Onelli MR, et al. E2F1-regulated microRNAs impair TGFβ-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008;13:272-86.
15. Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008;132:875-86.
16. Koralov SB, Muljo SA, Galler GR, et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 2008;132:860-74.
17. Xiao C, Srinivasan L, Calado DP, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 2008;9:405-14.
18. O'Donnell KA, Wentzel EA, Zeller KI, et al. c-MYC-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-43.
19. Dews M, Homayouni A, Yu D, et al. Augmentation of tumor angiogenesis by a MYC-activated microRNA cluster. Nat Genet 2006;38:1060-5.
20. Egle A, Harris AW, Bouillet P, et al. BIM is a suppressor of MYC-induced mouse B cell leukemia. Proc Natl Acad Sci US A 2004;101:6164-9.
21. Ivanovska I, Ball AS, Diaz RL, et al. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol 2008;28:2167-74.
22. Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007;449:682-8.