Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 4, 2008, Pages

  Broughton, Brad R S ^a   Walker, Benjimen R ^a   Resta, Thomas C ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Ca 2+ sensitization; HA 1077; Protein kinase C; Pulmonary hypertension; Vascular smooth muscle

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; CALCIUM; FASUDIL; FURA 2; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RHO KINASE; RHO KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DISEASE SEVERITY; HYPOXIA; INTESTINE PRESSURE; LUNG ALVEOLUS EPITHELIUM; LUNG VASOCONSTRICTION; MALE; MUSCLE CONTRACTION; MUSCLE TONE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; VASCULAR SMOOTH MUSCLE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANOXIA; ENDOTHELIUM, VASCULAR; MALE; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE INHIBITORS; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES;

EID: 42049083338     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00253.2007     Document Type: Article

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