Superoxide generated at mitochondrial complex iii triggers acute responses to hypoxia in the pulmonary circulation

American Journal of Respiratory and Critical Care Medicine

Volumn 187, Issue 4, 2013, Pages 424-432

  Waypa, Gregory B ^a   Marks, Jeremy D ^b   Guzy, Robert D ^a   Mungai, Paul T ^a   Schriewer, Jacqueline M ^a   Dokic, Danijela ^a   Ball, Molly K ^a   Schumacker, Paul T ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Hypoxic pulmonary vasoconstriction; Oxygen sensing; Reactive oxygen species; Rieske iron sulfur protein; RoGFP

Indexed keywords

IRON SULFUR PROTEIN; REACTIVE OXYGEN METABOLITE; TAMOXIFEN; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL TISSUE; ARTICLE; CYTOSOL; GENE DELETION; HYPOXIA; IN VIVO STUDY; LUNG CIRCULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASOCONSTRICTION;

ANIMALS; ANOXIA; CYTOSOL; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT COMPLEX III; LUNG; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MYOCYTES, SMOOTH MUSCLE; PULMONARY ARTERY; PULMONARY CIRCULATION; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 84873962657     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201207-1294OC     Document Type: Article

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