Role for PKCβ in enhanced endothelin-1-induced pulmonary vasoconstrictor reactivity following intermittent hypoxia

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 301, Issue 5, 2011, Pages

  Snow, Jessica B ^a   Gonzalez Bosc, Laura V ^a   Kanagy, Nancy L ^a   Walker, Benjimen R ^a   Resta, Thomas C ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Ca 2+ sensitization; Pulmonary hypertension; Rho kinase; Sleep apnea

Indexed keywords

CALCIUM ION; CARBON DIOXIDE; ENDOTHELIN 1; FASUDIL; FURA 2 ACETOXYMETHYL ESTER; MESSENGER RNA; OXYGEN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; RHO KINASE; ROTTLERIN; RUBOXISTAURIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CALCIUM CELL LEVEL; CELL DISRUPTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME LOCALIZATION; GENE TRANSLOCATION; HYPOXIA; INTERMITTENT HYPOXIA; LUNG ARTERY PRESSURE; LUNG VASOCONSTRICTION; MALE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SHAM PROCEDURE; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANOXIA; BLOOD GAS ANALYSIS; BLOTTING, WESTERN; CALCIUM; ENDOTHELIN-1; FURA-2; GENE EXPRESSION REGULATION; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE INHIBITORS; PULMONARY ARTERY; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 80055117706     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00020.2011     Document Type: Article

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