Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization

Cardiovascular Research

Volumn 99, Issue 3, 2013, Pages 404-411

  Kizub, Igor V ^a,b   Strielkov, Ievgen V ^a   Shaifta, Yasin ^b   Becker, Silke ^b   Prieto Lloret, Jesus ^b   Snetkov, Vladimir A ^b   Soloviev, Anatoly I ^a   Aaronson, Philip I ^b   Ward, Jeremy P T ^b  

^a STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

18 glycyrrhetinic acid; Ca2+ sensitization; Gap junctions; Hypoxic pulmonary vasoconstriction; Pulmonary artery

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CALCIUM; DILTIAZEM; GLUCOSE; GLYCYRRHETINIC ACID; HEPTANOL; PROSTAGLANDIN F2 ALPHA; RHO KINASE; 18ALPHA-GLYCYRRHETINIC ACID; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R12A PROTEIN, RAT; 18ALPHA GLYCYRRHETINIC ACID; DRUG DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; CALCIUM SENSITIZATION; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BLOOD LEVEL; ENZYME PHOSPHORYLATION; GAP JUNCTION; GLYCOLYSIS; HEART RIGHT VENTRICLE PRESSURE; HYPOXIC LUNG VASOCONSTRICTION; HYPOXIC PRESSOR RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INTRAPULMONARY ARTERY; MALE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; SENSITIZATION; SMOOTH MUSCLE; ANALOGS AND DERIVATIVES; ANIMAL; ANOXIA; BLOOD PRESSURE; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PULMONARY ARTERY; SIGNAL TRANSDUCTION; VASOCONSTRICTION; WISTAR RAT; 18Β-GLYCYRRHETINIC ACID; CA2+ SENSITIZATION; DRUG EFFECT;

ANIMALS; ANOXIA; BLOOD PRESSURE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; DILTIAZEM; GAP JUNCTIONS; GLYCYRRHETINIC ACID; MALE; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PULMONARY ARTERY; RATS; RATS, WISTAR; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

18Β-GLYCYRRHETINIC ACID; CA2+ SENSITIZATION; GAP JUNCTIONS; HYPOXIC PULMONARY VASOCONSTRICTION; PULMONARY ARTERY;

EID: 84894456938     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt129     Document Type: Article

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