Rho-kinase activation is involved in hypoxia-induced pulmonary vasoconstriction

American Journal of Respiratory Cell and Molecular Biology

Volumn 25, Issue 5, 2001, Pages 628-635

  Wang, Z ^a   Jin, N ^a   Ganguli, S ^a   Swartz, D R ^a   Li, L ^a   Rhoades, R A ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0035180564     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.25.5.4461     Document Type: Article

References (46)

1. Hypoxia on the pulmonary circulation: How and where it acts
2. Hypoxic contraction of isolated rat pulmonary artery
3. Contrasting effects of hypoxia on tension in rat pulmonary and mesenteric arteries
4. Pulmonary arterial hypoxic contraction: Signal transduction
5. Hypoxic contraction of cultured pulmonary vascular smooth muscle cells
6. Effects of hypoxia and other vasoactive agents on pulmonary and cerebral artery smooth muscle cells
7. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction
8. Hypoxia reduces potassium currents in cultured rat pulmonary but not mesenteric arterial myocytes
9. Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells
10. Hypoxic vasoconstriction and intracellular Ca2+ in pulmonary arteries: Evidence for PKC-independent Ca2+ sensitization
11. Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes
12. Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes
13. Pulmonary artery smooth muscle cell [Ca2+]i and contraction: Responses to diphenyleneiodonium and hypoxia
14. The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
15. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
16. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
17. The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid- GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle
18. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
19. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
20. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
21. Rho-associated kinase of chicken gizzard smooth muscle
22. Rho-kinase activation is involved in hypoxia-induced pulmonary vasoconstriction
23. Inhibition of sustained hypoxic vasoconstriction by Y-27632 in isolated intrapulmonary arteries and perfused lung of the rat
24. Hypoxia-induced pulmonary arterial contraction appears to be dependent on myosin light chain phosphorylation
25. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
26. Expression of rho A and rho kinase mRNAs in porcine vascular smooth muscle
27. Effect of a calcium sensitization modulator. Y-27632, on isolated human bronchus and pulmonary artery
28. Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm
29. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
30. Mechanisms of hypoxic pulmonary vasoconstriction: Can anyone be right?
31. Bacterial toxins inhibiting or activating small GTP-binding proteins
32. Regulation of endothelial cell myosin light chain kinase by Rho, cortactin, and p60(src)
33. Involvement of small GTPases in the regulation of smooth muscle contraction
34. Signaling to Rho GTPases
35. Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction
36. Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle
37. Constitutively active Galpha12, Galpha13, and Galphaq induce Rho-dependent neurite retraction through different signaling pathways
38. Redox status in the control of pulmonary vascular tone
39. Pulmonary artery NADPH-oxidase is activated in hypoxic pulmonary vasoconstriction
40. A membrane electrical mechanism for hypoxic vasoconstriction of small pulmonary arteries from cat
41. The role of tyrosine kinase in hypoxic constriction of sheep pulmonary artery rings
42. Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction
43. Hypoxia inhibits myosin phosphatase in pulmonary arterial smooth muscle cells
44. The contractile apparatus of airway smooth muscle: Biophysics and biochemistry
45. Divergent differentiation paths in airway smooth muscle culture: Induction of functionally contractile myocytes
46. A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea