메뉴 건너뛰기




Volumn 127, Issue 5, 2006, Pages 917-928

Identification of an Intestinal Folate Transporter and the Molecular Basis for Hereditary Folate Malabsorption

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FOLATE TRANSPORTER; FOLIC ACID; UNCLASSIFIED DRUG;

EID: 33751244559     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.09.041     Document Type: Article
Times cited : (702)

References (30)
  • 1
    • 0026545612 scopus 로고
    • Potocytosis: Sequestration and transport of small molecules by caveolae
    • Anderson R.G.W., Kamen B.A., Rothberg K.G., and Lacey S.W. Potocytosis: Sequestration and transport of small molecules by caveolae. Science 255 (1992) 410-411
    • (1992) Science , vol.255 , pp. 410-411
    • Anderson, R.G.W.1    Kamen, B.A.2    Rothberg, K.G.3    Lacey, S.W.4
  • 2
    • 0020623314 scopus 로고
    • The molecular mechanism of action of the proton ionophore FCCP (carbonylcyanide p-trifluoromethoxyphenylhydrazone)
    • Benz R., and McLaughlin S. The molecular mechanism of action of the proton ionophore FCCP (carbonylcyanide p-trifluoromethoxyphenylhydrazone). Biophys. J. 41 (1983) 381-398
    • (1983) Biophys. J. , vol.41 , pp. 381-398
    • Benz, R.1    McLaughlin, S.2
  • 3
    • 0037151112 scopus 로고    scopus 로고
    • Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters
    • Boll M., Foltz M., Rubio-Aliaga I., Kottra G., and Daniel H. Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters. J. Biol. Chem. 277 (2002) 22966-22973
    • (2002) J. Biol. Chem. , vol.277 , pp. 22966-22973
    • Boll, M.1    Foltz, M.2    Rubio-Aliaga, I.3    Kottra, G.4    Daniel, H.5
  • 4
    • 33646050916 scopus 로고    scopus 로고
    • Folic acid: A public-health challenge
    • Eichholzer M., Tonz O., and Zimmermann R. Folic acid: A public-health challenge. Lancet 367 (2006) 1352-1361
    • (2006) Lancet , vol.367 , pp. 1352-1361
    • Eichholzer, M.1    Tonz, O.2    Zimmermann, R.3
  • 5
    • 0036143484 scopus 로고    scopus 로고
    • Hereditary folate malabsorption: Family report and review of the literature
    • Geller J., Kronn D., Jayabose S., and Sandoval C. Hereditary folate malabsorption: Family report and review of the literature. Medicine (Baltimore) 81 (2002) 51-68
    • (2002) Medicine (Baltimore) , vol.81 , pp. 51-68
    • Geller, J.1    Kronn, D.2    Jayabose, S.3    Sandoval, C.4
  • 6
    • 0037427972 scopus 로고    scopus 로고
    • The superfamily of organic anion transporting polypeptides
    • Hagenbuch B., and Meier P.J. The superfamily of organic anion transporting polypeptides. Biochim. Biophys. Acta 1609 (2003) 1-18
    • (2003) Biochim. Biophys. Acta , vol.1609 , pp. 1-18
    • Hagenbuch, B.1    Meier, P.J.2
  • 7
    • 0030614893 scopus 로고    scopus 로고
    • Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
    • Helmlinger G., Yuan F., Dellian M., and Jain R.K. Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation. Nat. Med. 3 (1997) 177-182
    • (1997) Nat. Med. , vol.3 , pp. 177-182
    • Helmlinger, G.1    Yuan, F.2    Dellian, M.3    Jain, R.K.4
  • 8
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
    • Hidalgo I.J., Raub T.J., and Borchardt R.T. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96 (1989) 736-749
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 9
    • 0027477407 scopus 로고
    • Transport of folates and antifolates in liver
    • Horne D.W. Transport of folates and antifolates in liver. Proc. Soc. Exp. Biol. Med. 202 (1993) 385-391
    • (1993) Proc. Soc. Exp. Biol. Med. , vol.202 , pp. 385-391
    • Horne, D.W.1
  • 10
    • 33646828912 scopus 로고    scopus 로고
    • State-dependent cross-linking of the M2 and M3 segments: Functional basis for the alignment of GABAA and acetylcholine receptor M3 segments
    • Jansen M., and Akabas M.H. State-dependent cross-linking of the M2 and M3 segments: Functional basis for the alignment of GABAA and acetylcholine receptor M3 segments. J. Neurosci. 26 (2006) 4492-4499
    • (2006) J. Neurosci. , vol.26 , pp. 4492-4499
    • Jansen, M.1    Akabas, M.H.2
  • 11
    • 1242295185 scopus 로고    scopus 로고
    • The SLC22 drug transporter family
    • Koepsell H., and Endou H. The SLC22 drug transporter family. Pflugers Arch. 447 (2004) 666-676
    • (2004) Pflugers Arch. , vol.447 , pp. 666-676
    • Koepsell, H.1    Endou, H.2
  • 12
    • 0000980610 scopus 로고
    • Intestinal absorption of folate
    • Johnson L.R. (Ed), Raven Press, New York
    • Mason J.B., and Rosenberg I.H. Intestinal absorption of folate. In: Johnson L.R. (Ed). Physiology of the Gastrointestinal Tract (1994), Raven Press, New York 1979-1995
    • (1994) Physiology of the Gastrointestinal Tract , pp. 1979-1995
    • Mason, J.B.1    Rosenberg, I.H.2
  • 13
    • 0025376172 scopus 로고
    • Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine
    • Mason J.B., Shoda R., Haskell M., Selhub J., and Rosenberg I.H. Carrier affinity as a mechanism for the pH-dependence of folate transport in the small intestine. Biochim. Biophys. Acta 1024 (1990) 331-335
    • (1990) Biochim. Biophys. Acta , vol.1024 , pp. 331-335
    • Mason, J.B.1    Shoda, R.2    Haskell, M.3    Selhub, J.4    Rosenberg, I.H.5
  • 14
    • 0041305877 scopus 로고    scopus 로고
    • Membrane transport of folates
    • Matherly L.H., and Goldman D.I. Membrane transport of folates. Vitam. Horm. 66 (2003) 403-456
    • (2003) Vitam. Horm. , vol.66 , pp. 403-456
    • Matherly, L.H.1    Goldman, D.I.2
  • 16
    • 0021281777 scopus 로고
    • Endosome pH measured in single cells by dual fluorescence flow cytometry: Rapid acidification of insulin to pH 6
    • Murphy R.F., Powers S., and Cantor C.R. Endosome pH measured in single cells by dual fluorescence flow cytometry: Rapid acidification of insulin to pH 6. J. Cell Biol. 98 (1984) 1757-1762
    • (1984) J. Cell Biol. , vol.98 , pp. 1757-1762
    • Murphy, R.F.1    Powers, S.2    Cantor, C.R.3
  • 17
    • 29344433010 scopus 로고    scopus 로고
    • Analysis of 5-methyltetrahydrofolate in serum of healthy children
    • Opladen T., Ramaekers V.T., Heimann G., and Blau N. Analysis of 5-methyltetrahydrofolate in serum of healthy children. Mol. Genet. Metab. 87 (2006) 61-65
    • (2006) Mol. Genet. Metab. , vol.87 , pp. 61-65
    • Opladen, T.1    Ramaekers, V.T.2    Heimann, G.3    Blau, N.4
  • 18
    • 9444279605 scopus 로고    scopus 로고
    • Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery
    • Paulos C.M., Reddy J.A., Leamon C.P., Turk M.J., and Low P.S. Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery. Mol. Pharmacol. 66 (2004) 1406-1414
    • (2004) Mol. Pharmacol. , vol.66 , pp. 1406-1414
    • Paulos, C.M.1    Reddy, J.A.2    Leamon, C.P.3    Turk, M.J.4    Low, P.S.5
  • 20
    • 2342505952 scopus 로고    scopus 로고
    • Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins
    • Said H.M. Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins. Annu. Rev. Physiol. 66 (2004) 419-446
    • (2004) Annu. Rev. Physiol. , vol.66 , pp. 419-446
    • Said, H.M.1
  • 21
    • 0019498699 scopus 로고
    • Folate transport in isolated brush border membrane vesicles from rat intestine
    • Selhub J., and Rosenberg I.H. Folate transport in isolated brush border membrane vesicles from rat intestine. J. Biol. Chem. 256 (1981) 4489-4493
    • (1981) J. Biol. Chem. , vol.256 , pp. 4489-4493
    • Selhub, J.1    Rosenberg, I.H.2
  • 22
    • 0034098780 scopus 로고    scopus 로고
    • Rapid determination of membrane transport parameters in adherent cells
    • Sharif K.A., and Goldman I.D. Rapid determination of membrane transport parameters in adherent cells. Biotechniques 28 (2000) 926-928
    • (2000) Biotechniques , vol.28 , pp. 926-928
    • Sharif, K.A.1    Goldman, I.D.2
  • 24
    • 3142774934 scopus 로고    scopus 로고
    • Physiology of folate and vitamin B12 in health and disease
    • Stover P.J. Physiology of folate and vitamin B12 in health and disease. Nutr. Rev. 62 (2004) S3-S12
    • (2004) Nutr. Rev. , vol.62
    • Stover, P.J.1
  • 25
    • 4644224936 scopus 로고    scopus 로고
    • Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier
    • Wang Y., Zhao R., and Goldman I.D. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier. Clin. Cancer Res. 10 (2004) 6256-6264
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6256-6264
    • Wang, Y.1    Zhao, R.2    Goldman, I.D.3
  • 26
    • 10644265252 scopus 로고    scopus 로고
    • Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function
    • Wang Y., Rajgopal A., Goldman I.D., and Zhao R. Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function. Am. J. Physiol. Cell Physiol. 288 (2005) C65-C71
    • (2005) Am. J. Physiol. Cell Physiol. , vol.288
    • Wang, Y.1    Rajgopal, A.2    Goldman, I.D.3    Zhao, R.4
  • 27
    • 0021732164 scopus 로고
    • The relevance of tumour pH to the treatment of malignant disease
    • Wike-Hooley J.L., Haveman J., and Reinhold H.S. The relevance of tumour pH to the treatment of malignant disease. Radiother. Oncol. 2 (1984) 343-366
    • (1984) Radiother. Oncol. , vol.2 , pp. 343-366
    • Wike-Hooley, J.L.1    Haveman, J.2    Reinhold, H.S.3
  • 28
    • 0842304934 scopus 로고    scopus 로고
    • A prominent low-pH methotrexate transport activity in human solid tumor cells: Contribution to the preservation of methotrexate pharmacological activity in HeLa cells lacking the reduced folate carrier
    • Zhao R., Gao F., Hanscom M., and Goldman I.D. A prominent low-pH methotrexate transport activity in human solid tumor cells: Contribution to the preservation of methotrexate pharmacological activity in HeLa cells lacking the reduced folate carrier. Clin. Cancer Res. 10 (2004) 718-727
    • (2004) Clin. Cancer Res. , vol.10 , pp. 718-727
    • Zhao, R.1    Gao, F.2    Hanscom, M.3    Goldman, I.D.4
  • 29
    • 11144237445 scopus 로고    scopus 로고
    • Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier
    • Zhao R., Chattopadhyay S., Hanscom M., and Goldman I.D. Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier. Clin. Cancer Res. 10 (2005) 8735-8742
    • (2005) Clin. Cancer Res. , vol.10 , pp. 8735-8742
    • Zhao, R.1    Chattopadhyay, S.2    Hanscom, M.3    Goldman, I.D.4
  • 30
    • 23844507754 scopus 로고    scopus 로고
    • The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells
    • Zhao R., Hanscom M., and Goldman I.D. The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells. Biochim. Biophys. Acta 1715 (2005) 57-64
    • (2005) Biochim. Biophys. Acta , vol.1715 , pp. 57-64
    • Zhao, R.1    Hanscom, M.2    Goldman, I.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.