Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1

Nature Medicine

Volumn 13, Issue 4, 2007, Pages 448-454

  Ludwiczek, Susanne ^a   Theurl, Igor ^a   Muckenthaler, Martina U ^b   Jakab, Martin ^a,c   Mair, Sabine M ^a   Theurl, Milan ^a   Kiss, Judit ^b   Paulmichl, Markus ^a,d   Hentze, Matthias W ^e   Ritter, Markus ^a,c   Weiss, Guenter ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c PARACELSUS MEDICAL UNIVERSITY   (Austria)

^d UNIVERSITY OF MILAN   (Italy)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; IRON; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; NIFEDIPINE; CATION TRANSPORT PROTEIN; SOLUTE CARRIER FAMILY 11 (PROTON COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; IRON KINETICS; IRON OVERLOAD; IRON TRANSPORT; KIDNEY; LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; URINARY EXCRETION; ACTIVE TRANSPORT; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; COMPARATIVE STUDY; DRUG EFFECT; ELECTROPHYSIOLOGY; HEMOCHROMATOSIS; IMMUNOBLOTTING; METABOLISM; MICROARRAY ANALYSIS; MOUSE; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINE;

MUS;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CALCIUM CHANNEL BLOCKERS; CATION TRANSPORT PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; ELECTROPHYSIOLOGY; HEMOCHROMATOSIS; HUMANS; IMMUNOBLOTTING; IRON; IRON OVERLOAD; LIVER; MICE; MICE, KNOCKOUT; MICROARRAY ANALYSIS; NIFEDIPINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 34147145982     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1542     Document Type: Article

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