Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome c release after spinal cord injury

Journal of Neurotrauma

Volumn 31, Issue 6, 2014, Pages 582-594

  Lee, Jee Y ^a   Maeng, Sejung ^a   Kang, So R ^a   Choi, Hye Y ^a   Oh, Tae H ^a   Ju, Bong G ^b   Yune, Tae Y ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Sogang University   (South Korea)

Author keywords

Bcl 2; cytochrome c; JNK; oxidative stress; SCI

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BIM PROTEIN; CASPASE 12; CASPASE 9; CYTOCHROME C; INDUCIBLE NITRIC OXIDE SYNTHASE; OXYGEN; PORPHYRIN DERIVATIVE; PROTEIN MCL 1; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; MOTONEURON; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SPINAL CORD INJURY;

ANIMALS; CELL DEATH; CYTOCHROMES C; ENDOPLASMIC RETICULUM STRESS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPINAL CORD INJURIES; VALPROIC ACID;

EID: 84896367457     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2013.3146     Document Type: Article

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