Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice

Journal of Molecular Medicine

Volumn 86, Issue 11, 2008, Pages 1243-1254

  Tsai, Li Kai ^a   Tsai, Ming Shiun ^b   Ting, Chen Hung ^c   Li, Hung ^c,d  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b DA YEH UNIVERSITY   (Taiwan)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Animal model; Apoptosis; Motor neuron disease; Neurogenesis; Spinal muscular atrophy; Valproic acid

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2; PROTEIN BCL X; SURVIVAL MOTOR NEURON PROTEIN; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONTROLLED STUDY; EVOKED MUSCLE RESPONSE; MOTONEURON; MOTOR PERFORMANCE; MOUSE; MUSCLE ATROPHY; NERVOUS SYSTEM DEVELOPMENT; NEUROMUSCULAR SYNAPSE; NEUROPROTECTION; NONHUMAN; SPINAL CORD NERVE CELL; SPINAL MUSCULAR ATROPHY;

ANIMALS; ASTROCYTES; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCLE FIBERS, SKELETAL; MUSCULAR ATROPHY, SPINAL; NEUROGENESIS; NEUROMUSCULAR JUNCTION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-BCL-2; SMN COMPLEX PROTEINS; SPINAL CORD; SURVIVAL OF MOTOR NEURON 1 PROTEIN; VALPROIC ACID;

EID: 54249110856     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0388-1     Document Type: Article

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