Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis

Brain Research

Volumn 1092, Issue 1, 2006, Pages 36-46

  Guan, Qiu Hua ^a,b   Pei, Dong Sheng ^b   Liu, Xiao Mei ^a   Wang, Xiao Tian ^a   Xu, Tian Le ^b,c   Zhang, Guang Yi ^a,b  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

c Jun N terminal protein kinase (JNK); Cerebral ischemia reperfusion; Extrinsic and intrinsic pathways of apoptosis; SP600125

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CYTOCHROME C; FAS LIGAND; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; MALE; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

ANIMALS; ANTHRACENES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; CASPASE 3; CASPASES; CEREBRAL INFARCTION; CYTOCHROMES C; ENZYME INHIBITORS; FAS LIGAND PROTEIN; HIPPOCAMPUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MEMBRANE GLYCOPROTEINS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTORS;

EID: 33745150702     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.03.086     Document Type: Article

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