Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway

Journal of Cerebral Blood Flow and Metabolism

Volumn 25, Issue 6, 2005, Pages 694-712

  Gao, Yanqin ^a,b   Signore, Armando P ^a   Yin, Wei ^a   Cao, Guodong ^a   Yin, Xiao Ming ^a   Sun, Fengyan ^b   Luo, Yumin ^a   Graham, Steven H ^a,c   Chen, Jun ^a,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b FUDAN UNIVERSITY   (China)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bax; Bim; Caspase 3; Caspase 9; Cytochrome c

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BIM PROTEIN; CASPASE 3; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; FAS LIGAND; PROTEIN BAX; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOPRECIPITATION; MEDIATOR RELEASE; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

14-3-3 PROTEINS; ANIMALS; ANTHRACENES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; CARRIER PROTEINS; CEREBRAL INFARCTION; ENZYME INHIBITORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 18944381512     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600062     Document Type: Article

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